Kojic acid - A new leading molecule for a preparation of compounds with an anti-neoplastic potential

Neoplasma

Volumn 46, Issue 2, 1999, Pages 89-92

  Novotny L ^a   Rauko, P ^b   Abdel Hamid, M ^a   Vachalkova A ^b  

^a KUWAIT UNIVERSITY   (Kuwait)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Antifungal activity; Antileukemic activity; Kojic acid; Kojic acid derivatives

Indexed keywords

5 BENZYLOXY 2 THIOCYANATOMETHYL 4 PYRANONE; KOJIC ACID; PYRAN DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ASPERGILLUS; BIODEGRADATION; CANCER CHEMOTHERAPY; CHELATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; LEUKEMIA; PENICILLIUM; SHORT SURVEY; STRUCTURE ACTIVITY RELATION;

EID: 0033057550     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (30)

1. BAJPAI, P., AGRAWAL, P.K., VISHWANATHAN, L.: Kojic acid: Synthesis and properties. J. Sci. Indust. Res., 41, 1982, 185-194.
2. BALÁŽ, S., ŠTURDÍK, E., UJHÉLYIOVA, R., VALIGURA, D., UHER, M., VEVERKA, M., KONEČNÝ, V., ADAMCOVÁ, J., MICHALÍK, P., BRTKO, J.: Biologically important physicochemical properties of kojic acid derivatives. Collect. Czech. Chem. Commun., 55, 1993, 693-701.
3. BALÁŽ, S., UHER, M., BRTKO, J., VEVERKA, M., BRANSOVÁ, J., DOBIAS, J., PODOVA, M., BUCHVALD, J.: Relationship between antifungal activity and hydrophobicity of kojic acid derivatives. Folia Microbiol., 38, 1993, 387-391.
4. BHAT, R., HADI, S.M.: Photoinduction of strand scissions in DNA by kojic acid: Role of transition metal ions and oxygen free radical intermediates in the reaction. Mutagenesis, 7, 1992, 119-124.
5. BRANSOVÁ, J., UHER, M., BRTKO, J.: Preparation of 5-substituted 4-oxo-4H-pyran-2-carbaldehydes and their condensation reactions. Chem. Papers, 47, 1993, 316-319.
6. BRANSOVÁ, J., UHER, M., BRTKO, J.: Preparation and study of reactions of the 5-substituted 4-oxo-4H-pyran-2-carboxylic acid. Chem. Papers, 48, 1994, 341-344.
7. BRANSOVÁ, J., BRTKO, J., UHER, M., NOVOTNÝ, L.: Antileukemic activity of 4-pyrazolon derivatives. Int. J. Biochem. Cell Biol., 27, 1995, 701-706.
8. BRANSOVÁ, J., UHER, M., NOVOTNÝ, L., BRTKO, J.: 5-Benzyloxy-2-thiocyanatomethyl-4-pyranone, a novel heterocyclic compound: Synthesis, structure determination and effects on neoplastic cell growth. Anticancer Res., 17, 1997, 1175-1178.
9. CHING, L.-M., BAGULEY, B.C.: Induction of natural killer cell activity by the antitumor compound flavone acetic acid. Eur. J. Cancer Clin. Oncol., 23, 1987, 1047-1050.
10. DOUGLAS, K.T., GOHEL, D.I., NADVI, I.N., QUILTER, A.J., SEDDON, A.P.: Partial transition-state inhibitors of glyoxalase I from human erythrocytes, yeast and rat liver. Biochim. Biophys. Acta, 829, 1985, 109-118.
11. EROL, D.D., CALIS, U., YULUG, N.: Synthesis and antimicrobial activities of some dithiocarbamate derivatives of kojic acid. Boll. Chim. Farm., 134, 1995, 620-623.
12. FUJIMOTO, N., WATANABE, H., NAKATANI, T., ROY, G., ITO, A.: Induction of thyroid tumours in (C57BL/6N×C3H/N)F1 mice by oral administration of kojic acid. Food Chem. Toxicol., 36, 1998, 697-703.
13. HAVSTEEN, B.: Flavonoids, a class of natural high pharmacologic potency. Biochem. Pharmacol., 32, 1983, 1141-1148.
14. HUDECOVÁ, D., JANTOVÁ, S., MELNIK, M., UHER, M.: New azidometalkojates and their biological activity. Folia Microbiol. (Praha), 4, 1996, 473-476.
15. KAHN, V., BEN-SHALOM, N.: N-acetyl-L-tyrosine (NAT) as a substrate for mushroom tyrosinase. Pigment Cell Res., 11, 1998, 24-33.
16. KAUR, G., STETLER-STEVENSON, M., SEBERS, S., WORLAND, P., SEDLACEK, H., MYERS, C., CZECH, J., NAIK, R., SAUSVILLE, E.: Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275. J. Natl. Cancer Inst., 84, 1992, 1736-1740.
17. KONTANI, T., ICHIMOTO, I., SAKAI, H.: Bacteriostatic activity and mode of action mechanism of kojic acid. Nippon Nogei Kagaku Kaishi, 56, 1982, 553-557.
18. MARWAHA, S.S., KAUR, J., SODHI, G.S.: Organomercury(II) complexes of kojic acid and maltol: Synthesis, characterization, and biological studies. J. Inorg. Biochem., 54, 1994, 67-74.
19. MOLENDA, J.J., BASINGER, M.A., HANUSA, T.P., JONES, M.M.: Synthesis and iron(III) binding properties of 3-hydroxypyrid-4-ones derived from kojic acid. J. Inorg. Biochem., 55, 1994, 131-146.
20. MORISAKI, K., OZAKI, S.: Design of novel hybrid vitamin C derivatives: Thermal stability and biological activity. Chem. Pharm. Bull. (Tokyo), 44, 1996, 1647-1655.
21. NAKAGAWA, M., KAWAI, K., KAVAI, K.: Contact allergy to kojic acid in skin care products. Contact Dermatitis, 32, 1995, 9-13.
22. PIRŠELOVÁ, K., BALÁŽ, S., UJHÉLYIOVÁ, R., ŠTURDÍK, E., VEVERKA, M., UHER, M., BRTKO, J.: Quantitative structure-time-activity relationships (QSTAR): Growth inhibition of Escherichia coli by nonionizable kojic acid derivatives. Quant. Struct.-Act. Relat., 15, 1996, 87-93.
23. NIWA, Y., AKAMATSU, H.: Kojic acid scavenges free radicals while potentiating leukocyte functions including free radical generation. Inflammation, 15, 1991, 303-315.
24. Sansei Pharmaceutical Co.: Kojic Acid. Japan Kokai Tokkyo Koho, J.P. 80127993, 1981.
25. Sansho Seiyaku Co.: Kojic Acid as an Antiinflammatory and Analgesic Agent. Japan Kokai Tokkyo Koho JP 80154916, 1980.
26. SHIBUYA, T., MUROTA, T., SAKAMOTO, K., IWAHARA, S., IKENO, M.: Mutagenicity and dominant lethal test of kojic acid -Ames test, forward mutation test in cultured Chinese hamsters cells and dominant lethal test in mice. J. Toxicol. Sci., 7, 1982, 255-262.
27. The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals. 12th ed. Ed.: Budari, S. Whitehouse Station, N.J., Merck Research Laboratories 1996, Article No. 5330, 907.
28. UHER, M., KYSELICOVÁ, L., RAJNIAKOVÁ, O., HUDECOVÁ, D., BRANSOVÁ, J., BRTKO, J.: Derivatives of 4H-pyran-4-one with the atom of sulfur in the side chain. Chem. Papers, 51, 1997, 421-426.
29. VACHÁLKOVÁ, A., BRANSOVÁ, J., BRTKO, J., UHER, M., NOVOTNÝ, L.: Polarographic properties of kojic acid derivatives and their potential carcinogenity. Neoplasma, 43, 1996, 265-269.
30. WEI, C.I., HUANG, T.S., FERNANDO, S.Y., CHUNG, K.T.: Mutagenicity studies of kojic acid. Toxicol. Lett., 59, 1991, 213-220.