Regulation of glucose transport by hypoxia

American Journal of Kidney Diseases

Volumn 34, Issue 1, 1999, Pages 189-202

  Zhang, J Z ^a   Behrooz, A ^a   Ismail Beigi, F ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Azide; Cell energetics; Cobalt; Glut1; Glut1 transcription; Glut3; Glut4; Hypoxia inducible factor 1 (HIF 1); Hypoxia signaling; Hypoxia responsive genes; Oxidative phosphorylation

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; MESSENGER RNA;

ARTICLE; CELL MEMBRANE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT SYSTEM; HYPOXIA; MAMMAL CELL; OXIDATIVE PHOSPHORYLATION; OXYGEN TENSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; TISSUE DISTRIBUTION;

EID: 0033056350     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0272-6386(99)70131-9     Document Type: Article

References (108)

1. J Elbrink I Bihler Membrane transport: Its relation to cellular metabolic rates Science 188 1975 1177 1184
2. F Ismail-Beigi Metabolic regulation of glucose transport J Membrane Biol 135 1993 1 10
3. PJ Randle GH Smith Regulation of glucose uptake by muscle. 1. The effects of insulin, anaerobiosis and cell poisons on the uptake of glucose and release of potassium by isolated rat diaphragm Biochem J 70 1958 490 500
4. HE Morgan PJ Randle DM Regen Regulation of glucose uptake by muscle. 3. The effects of insulin, anoxia, salicylate and 2:4-dinitrophenol on membrane transport and intracellular phosphorylation of glucose in the isolated rat heart Biochem J 73 1959 573 579
5. RE Wood HE Morgan Regulation of sugar transport in avian erythrocytes J Biol Chem 244 1969 1451 1460
6. E Morgan CF Whitfield Regulation of sugar transport in eukaryotic cells Curr Top Membr Transport 4 1973 255 303
7. CL Mercado JN Loeb F Ismail-Beigi Enhanced glucose transport in response to inhibition of respiration in Clone 9 cells Am J Physiol 257 1989 C19 C28
8. B Tune M Burg Glucose transport in proximal renal tubules Am J Physiol 221 1971 580 585
9. B Sacktor Sodium-coupled hexose transport Kidney Int 36 1989 342 350
10. E Wright B Hirayama D Loo D Turk K Hager Intestinal sugar transport ed 3 Johnson Physiology of Gastrointestinal Tract, vol II 1994 Raven Press New York, NY
11. M Mueckler C Caruso SA Baldwin M Panico I Blench HR Morris WJ Allard G Lienhard HF Lodish Sequence and structure of a human glucose transporter Science 229 1985 941 945
12. MJ Birnbaum HC Haspel OM Rosen Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein Proc Natl Acad Sci U S A 83 1986 5784 5788
13. M Mueckler Facilitative glucose transporters Eur J Biochem 219 1994 713 725
14. JE Pessin GI Bell Mammalian facilitative glucose transporter family: Structure and molecular regulation Annu Rev Physiol 54 1992 911 930
15. 2 in muscle cells in culture Am J Physiol 262 1992 C682 C690
16. M Becker S Newman F Ismail-Beigi Stimulation of Glut1 glucose transporter expression in response to inhibition of oxidative phosphorylation: Role of reduced sulfhydryl groups Mol Cell Endocrinol 121 1996 165 170
17. A Behrooz F Ismail-Beigi Dual control of glut1 glucose transporter gene expression by hypoxia and by inhibition of oxidative phosphorylation J Biol Chem 272 1997 5555 5562
18. MJ Birnbaum HC Haspel OM Rosen Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription Science 235 1987 1495 1498
19. JS Flier MM Mueckler P Usher HF Lodish Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes Science 235 1987 1492 1495
20. RS Haber F Ismail-Beigi JN Loeb Time-course of Na,K transport and other metabolic responses to thyroid hormone in Clone 9 cells Endocrinology 123 1988 238 247
21. J Hakimian F Ismail-Beigi Enhancement of glucose transport in Clone 9 cells by exposure to alkaline pH: Studies on potential mechanisms J Membrane Biol 120 1991 29 39
22. AK Kuruvilla C Perez F Ismail-Beigi JN Loeb Regulation of glucose transport in Clone 9 cells by thyroid hormone Biochim Biophys Acta 1094 1991 300 308
23. JD Loike L Cao J Brett S Ogawa SC Silverstein D Stern Hypoxia induces glucose transporter expression in endothelial cells Am J Physiol 263 1992 C326 C333
24. Y Mitani A Behrooz GR Dubyak F Ismail-Beigi Stimulation of GLUT1 glucose transporter expression in response to exposure to calcium ionophore A23187 Am J Physiol 269 1995 C1228 C1234
25. i Am J Physiol 270 1996 C235 C242
26. M Shetty AK Kuruvilla F Ismail-Beigi JN Loeb Stimulation of glucose transport in Clone 9 cells by insulin and thyroid hormone: Role of GLUT1 activation Biochim Biophys Acta 1314 1996 140 146
27. M Shetty JN Loeb F Ismail-Beigi Enhancement of glucose transport in response to inhibition of oxidative phosphorylation: Pre- and posttranslational mechanisms Am J Physiol 262 1992 C527 C532
28. E Wertheimer S Sasson E Cerasi Y Ben-Neriah The ubiquitous glucose transporter GLUT1 belongs to the glucose-regulated protein family of stress-inducible proteins Proc Natl Acad Sci U S A 88 1991 2525 2529
29. J Ybarra A Behrooz A Gabriel MH Köseoglu F Ismail-Beigi Glycemia-lowering effect of cobalt chloride in the diabetic rat: Increased GLUT1 mRNA expression Mol Cell Endocrinol 133 1997 151 160
30. A Carruthers Facilitated diffusion of glucose Physiol Rev 70 1990 1135 1175
31. A Hogan S Heyner M Charron N Copeland D Gilbert N Jenkins B Thorens G Schultz Glucose transporter gene expression in early mouse embryos Development 113 1991 363 372
32. C Postic A Leturque R Printz P Maulard M Loizeau D Granner J Girard Development and regulation of glucose transporter and hexokinase expression in rat Am J Physiol 266 1994 E548 E559
33. M Tal D Schneider B Thorens HF Lodish Restricted expression of the erythroid/brain glucose transporter isoform to perivenous hepatocytes in rats Am J Physiol 267 1990 E88 E94
34. A De Herreros M Birnbaum The regulation by insulin of glucose transporter gene expression in 3T3 adipocytes J Biol Chem 264 1989 9885 9890
35. A Marette JM Richardson T Ramlal TW Balon M Vranic JE Pessin A Klip Abundance, localization, and insulin-induced translocation of glucose transporters in red and white muscle Am J Physiol 263 1992 C443 C452
36. J Dominguez K Camp L Maianu T Garvey Glucose transporters of rat proximal tubule: Differential expression and subcellular distribution Am J Physiol 262 1992 F807 F812
37. WM Pardridge RJ Boado CR Farrell Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier: Studies with quantitative Western blotting and in situ hybridization J Biol Chem 265 1990 18035 18040
38. DZ Gerhart RL Leino WE Taylor ND Borson LR Drewes GLUT1 and GLUT3 gene expression in gerbil brain following brief ischemia: An in situ hybridization study Brain Res Mol Brain Res 25 1994 313 322
39. AL McCall AM Van Bueren V Nipper M Moholt-Siebert H Downes N Lessov Forebrain ischemia increases GLUT1 protein in brain microvessels and parenchyma J Cereb Blood Flow Metab 16 1996 69 76
40. SJ Vannuci R Reinhart F Maher CA Bondy WH Lee RC Vannucci IA Simpson Alterations in GLUT1 and GLUT3 glucose transporter gene expression following unilateral hypoxia-ischemia in the immature rat brain Brain Res Dev Brain Res 107 1998 255 264
41. BC Shin K Fujikura T Suzuki S Tanaka K Takata Glucose transporter GLUT3 in the rat placental barrier: A possible machinery for the transplacental transfer of glucose Endocrinology 138 1997 3997 4004
42. K Takata T Kasahara M Kasahara O Ezaki H Hirano Ultracytochemical localization of the erythrocyte/HepG2-type glucose transporter (GLUT1) in cells of the blood-retinal barrier in the rat Invest Ophthalmol Vis Sci 33 1992 377 383
43. A Kumagai S Vinores W Pardridge Pathological upregulation of inner blood-retinal barrier Glut1 glucose transporter expression in diabetes mellitus Brain Res 706 1996 313 317
44. B Thorens HK Sarkar HR Kaback HF Lodish Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells Cell 55 1988 281 290
45. GW Gould AM Brant BB Kahn PR Shepherd SC McCoid EM Gibbs Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice Diabetologia 35 1992 304 309
46. S Nagamatsu JM Kornhauser CF Burant S Seino KE Mayo GI Bell Glucose transporter expression in brain: cDNA sequence of mouse GLUT3, the brain facilitative glucose transporter isoform, and identification of sites of expression by in situ hybridization J Biol Chem 267 1992 467 472
47. ZA Khayat AL McCall A Klip Unique mechanism of Glut3 glucose transporter regulation by prolonged energy demand: Increased protein half-life Biochem J 333 1998 713 718
48. MJ Birnbaum The insulin sensitive glucose transporter Int Rev Cytol 137 1992 239 297
49. F Kanani K Ito M Todaka H Hayashi S Kamohara K Ishii T Okada O Hazeki M Ui Y Ebina Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase Biochem Biophys Res Commun 195 1993 762 768
50. PR Shepherd DJ Withers K Siddle Phosphoinositide 3-kinase: The key switch mechanism in insulin signalling Biochem J 333 1998 471 490
51. BH Jhun AL Ranpal H Liu M Lachaal CY Jung Effects of insulin on steady state kinetics of GLUT4 subcellular distribution in rat adipocytes: Evidence of constitutive GLUT4 recycling J Biol Chem 267 1992 17710 17715
52. JL Azevedao JO Carey WJ Pories PG Morris GL Dohm Hypoxia stimulates glucose transport in insulin-resistant skeletal muscle Diabetes 44 1995 695 698
53. AD Lee PA Hansen JO Holloszy Wortmannin inhibits insulin-stimulated but not contraction-stimulated glucose transport activity in skeletal muscle FEBS Lett 361 1995 51 54
54. JM Stephens PF Pilch The metabolic regulation and vesicular transport of Glut4, the major insulin-responsive glucose transporter Endocrine Rev 16 1995 529 546
55. JF Wojtaszewski JL Laustsen W Derave EA Richter Hypoxia and contractions do not utilize the same signaling mechanism in stimulating skeletal muscle glucose transport Biochim Biophys Acta 1380 1998 396 404
56. JI Yeh EA Gulve L Rameh MJ Birnbaum The effects of wortmannin on rat skeletal muscle: Dissociation of signaling pathways for insulin- and contraction-activated hexose transport J Biol Chem 270 1995 2107 2111
57. A Burchell A reevaluation of Glut7 Biochem J 331 1998 973
58. S Rogers DE James JD Best Identification of a novel facilitative glucose transporter like protein-Glut8 Diabetes 47 1998 45A (abstr)
59. D Voet JG Voet Biochemistry ed 2 1995 Wiley & Sons New York, NY
60. DP Jones New concepts of the molecular pathogenesis from hypoxia TE King HS Mason M Morrison Oxidases and Related Redox Systems 1988 Alan Liss New York, NY 127 144
61. KM Gaudio G Thulin NJ Siegel Immature tubules are tolerant of oxygen deprivation Pediatr Nephrol 11 1997 757 760
62. A Sahai C Mei TA Pattison RL Tannen Chronic hypoxia induces proliferation of cultured mesangial cells: Role of calcium and protein kinase C Am J Physiol 273 1997 F954 F960
63. CC Tan PJ Ratcliffe Effect of inhibition of oxidative phosphorylation on erythropoietin mRNA in isolated perfused rat kidneys Am J Physiol 261 1991 F982 F987
64. MA Goldberg SP Dunning HF Bunn Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein Science 242 1988 1412 1415
65. GL Wang GL Semenza General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia Proc Natl Acad Sci U S A 90 1993 4304 4308
66. 2 tension Proc Natl Acad Sci U S A 92 1995 5510 5514
67. M Gassman RH Wenger HIF-1, a mediator of the molecular response to hypoxia News Physiol Sci 12 1997 214 218
68. E Necas EB Thorling Unresponsiveness of erythropoietin-producing cells to cyanide Am J Physiol 222 1972 1187 1990
69. GL Semenza PH Roth H-M Fang GL Wang Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 J Biol Chem 269 1994 23757 23763
70. E Maltepe JV Schmidt D Baunoch CA Bradfield M Celeste-Simon Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT Nature 386 1997 403 406
71. K Guillemin MA Krasnow The hypoxic response: Huffing and HIFing Cell 89 1997 9 12
72. RH Wenger M Gassmann Oxygen(es) and the hypoxia-inducible factor-1 Biol Chem 378 1997 609 616
73. BL Ebert JD Firth PJ Ratcliffe Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct cis-acting sequences J Biol Chem 270 1995 29083 29089
74. M Shetty N Ismail-Beigi JN Loeb F Ismail-Beigi Induction of GLUT1 mRNA in response to inhibition of oxidative phosphorylation Am J Physiol 265 1993 C1224 C1229
75. DL Diamond A Carruthers Metabolic control of sugar transport by derepression of cell surface glucose transporters J Biol Chem 268 1993 6437 6444
76. WF Widdas Old and new concepts of the membrane transport for glucose in cells Biochim Biophys Acta 947 1988 385 404
77. M Shetty JN Loeb K Vikstrom F Ismail-Beigi Rapid activation Glut-1 glucose transporter following inhibition of oxidative phosphorylation in Clone 9 cells J Biol Chem 268 1993 17225 17232
78. Y Shi H Liu G Vanderburg SJ Samuel F Ismail-Beigi CY Jung Modulation of GLUT1 intrinsic activity in Clone 9 cells by inhibition of oxidative phosphorylation J Biol Chem 270 1995 21772 21778
79. RJ Zottola EK Cloherty PE Coderre A Hansen DN Herbert A Carruthers Glucose transporter function is controlled by transporter oligomerization structure: A single intramolecular disulfide promotes Glut1 tetramerization Biochemistry 34 1995 9734 9747
80. JZ Zhang F Ismail-Beigi Activation Glut1 glucose transporter in human erythrocytes Arch Biochem Biophys 356 1998 86 92
81. SW Cushman LJ Wardzala Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell J Biol Chem 255 1980 4758 4762
82. K Suzuki T Kono Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage sight Proc Natl Acad Sci U S A 77 1980 2542 2545
83. NB Rudermann R Kapeller MF White LC Cantley Activation of phosphatidylinositol 3-kinase by insulin Proc Natl Acad Sci U S A 87 1990 1411 1415
84. TJ Wheeler Translocation of glucose transporters in response to anoxia in heart J Biol Chem 263 1988 19447 19454
85. TJ Wheeler RD Fell MA Hauck Translocation of two glucose transporters in heart: Effects of rotenone, uncouplers, workload, palmitate, insulin and anoxia Biochim Biophys Acta 1196 1994 191 200
86. DQ Sun N Nguyen TR DeGrado M Schwaiger FC Brosius Ischemia induces translocation of the insulin-responsive glucose transporter Glut4 to the plasma membrane of cardiac myocytes Circulation 89 1994 793 798
87. JR Zierath TS Tsao AE Stenbit JW Ryder D Galuska MJ Charron Restoration of hypoxia-stimulated glucose uptake in Glut4-deficient muscles by muscle-specific Glut4 transgenic complementation J Biol Chem 273 1998 20910 20915
88. RN Cortright JL Azevedo Jr MS Hickey EB Tapscott GL Dohm Vanadate stimulation of 2-deoxyglucose transport is not mediated by PI 3-kinase in human skeletal muscle Biochim Biophys Acta 1358 1997 300 306
89. MH Koseoglu F Ismail-Beigi Mechanism of stimulation of glucose transport in response to inhibition of oxidative phosphorylation: Analysis with myc-tagged Glut1 Mol Cell Biochem 194 1999 109 116
90. PA Hansen W Wang BA Marshall JO Holloszy M Mueckler Dissociation of Glut4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing Glut1 in skeletal muscle J Biol Chem 273 1998 18173 18179
91. EM Gibbs GE Lienhard GW Gould Insulin-induced translocation of glucose transporters to the plasma membrane precedes full stimulation of hexose transport Biochemistry 27 1988 6681 6685
92. E Karnieli WT Garvey JM Olefsky TP Hueckstead C Harel L Maianu M Armoni Potential role of insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes Endocrinology 133 1993 2943 2950
93. LA Witters CA Vater GE Lienhard Phosphorylation of the glucose transporter in vitro and in vivo by protein kinase C Nature 315 1985 777 778
94. MR Deziel HA Lippes AL Rampal CY Jung Phosphorylation of human erythrocyte glucose transporter by protein kinase C: localization of the site of in vivo and in vitro phosphorylation Int J Biochem 21 1989 807 814
95. WI Sivitz DD Lund B Yorek M Grover-McKay PG Schmid Pretranslational regulation of two cardiac glucose transporters in rats exposed to hypobaric hypoxia Am J Physiol 263 1992 E562 E569
96. C Taha T Tsakiridis A McCall A Klip Glucose transporter expression in L6 muscle cells: Regulation through insulin- and stress-activated pathways Am J Physiol 273 1997 E68 E76
97. SA Williams MJ Birnbaum The rat facilitated glucose transporter gene: Transformation and serum-stimulated transcription initiated from identical sites J Biol Chem 263 1988 19513 19518
98. T Murakami T Nishiyama T Shirotani Y Shinohara M Kan K Ishii F Kanai S Nakazuru Y Ebina Identification of two enhancer elements in the gene encoding the type 1 glucose transporter from the mouse which are responsive to serum, growth factors, and oncogenes J Biol Chem 267 1992 9300 9306
99. F Viñals C Fandos T Santalucia J Ferré X Testar M Palacín A Zorzano Myogenesis and myoD down-regulate Sp1: A mechanism for the repression of GLUT1 during muscle cell differentiation J Biol Chem 272 1997 12913 12921
100. I Stein M Neeman D Shweiki A Itin E Keshet Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes Mol Cell Biol 15 1995 5363 5368
101. G Shaw R Kamen A conserved AU sequence from the 3′-untranslated region GM-CSF mRNA mediates selective mRNA degradation Cell 46 1986 659 667
102. T Wilson R Treisman Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences Nature 336 1988 396 399
103. J Jackson Cytoplasmic regulation of mRNA function: The importance of the 3′ untranslated region Cell 74 1993 9 14
104. K Dwyer R Boado W Pardridge Cis-element/cytoplasmic protein interaction within the 3′-untranslated region of the GLUT1 glucose transporter mRNA J Neurochem 66 1996 449 458
105. JM Stephens PH Pekala Tumor necrosis factor α-induced glucose transporter (GLUT-1) mRNA stabilization in 3T3-L1 preadipocytes J Biol Chem 267 1992 13580 13584
106. NS Levy S Chung H Furneaux AP Levy Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR J Biol Chem 273 1997 6417 6423
107. CY Jung AL Rampal Cytochalasin B binding sites and glucose transport carrier in human erythrocyte ghosts J Biol Chem 252 1977 5456 5463
108. HB Pinofsky AL Rampal MA Cowden CY Jung Cytochalasin B binding protein in human erythrocyte membranes J Biol Chem 253 1978 4930 4937