Inhibition of human immunodeficiency virus type (HIV-1) replication by some diversely functionalized spirocyclopropyl derivatives

Archiv der Pharmazie

Volumn 332, Issue 5, 1999, Pages 163-166

  Witvrouw, Myriam ^a   Pannecouque, Christophe ^a   De Clercq, Erik ^a   Fernández Alvarez, Eldiberto ^b   Marco, José L ^b  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

Author keywords

HIV 1 inhibition; Reverse transcriptase; Spirocyclopropyl derivatives

Indexed keywords

1 [(2 HYDROXYETHOXY)METHYL] 6 (PHENYLTHIO)THYMINE; 2 BENZYL 4 CYANOMETHYLENE 1,1,3 TRIOXO 2H,4H THIENO[3,4 E][1,2,4]THIADIAZINE; ANTIRETROVIRUS AGENT; LOVIRIDE; NSC 287474; RITONAVIR; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TIVIRAPINE; TROVIRDINE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; VIRUS INHIBITION;

ANTI-HIV AGENTS; CELL LINE; CYCLOPROPANES; HIV-1; HIV-2; HUMANS; SIMIAN IMMUNODEFICIENCY VIRUS; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 0033053280     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(19995)332:5<163::AID-ARDP163>3.0.CO;2-2     Document Type: Article

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