Haemorheological disturbances and possibility of their correction in cerebrovascular diseases

Journal des Maladies Vasculaires

Volumn 24, Issue 2, 1999, Pages 110-116

  Forconi, S ^a   Turchetti, V ^a   Cappelli, R ^a   Guerrini, M ^a   Bicchi, M ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

Cerebrovascular diseases; Haemorheology

Indexed keywords

ARTICLE; BLOOD FLOW VELOCITY; BLOOD RHEOLOGY; BLOOD VISCOSITY; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; ERYTHROCYTE DEFORMABILITY; HEMATOCRIT; HUMAN; PATHOPHYSIOLOGY; STROKE;

AGED; BLOOD VISCOSITY; CALCIUM; CALCIUM CHANNEL BLOCKERS; CEREBROVASCULAR DISORDERS; CONTROLLED CLINICAL TRIALS; ERYTHROCYTES; HEMATOCRIT; HEMORHEOLOGY; HUMANS; NIMODIPINE;

EID: 0033052883     PISSN: 03980499     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (79)

1. ABE H, KADATA K, ORITA M, NISHIKIBE M. Effects of calcium antagonists on erythrocyte membrane. J Pharm Pharmacol, 1991; 43: 22-6 .
2. ALVAREZ G, VACAREZZA R. Cerebral vasodilators. Rev Med Chil, 1990; 118: 790-5.
3. APOLLONIO A, ANGELETTI R, MAGRINI L, CASTIGNANI P. Ticlopidine-pentoxifylline combination in the treatment of atherosclerosis and the prevention of cerebrovascular accidents. J Int Med Res, 1989; 17: 28-35.
4. ATKINS D, PSATY BM, KOEPSELL TD, LONGSTRETH WT Jr, LARSON EB. Cholesterol reduction and the risk for stroke in men. A meta-analysis of randomized, controlled trials. Ann Intern Med, 1993; 119: 136-45.
5. BOISSEAU MR, DUFOURQ P, SEIGNEUR M, ROUDAUT MF, BER TRAND A. Changes in cell behaviour during ischaemic cerebrovascular disease. Clin Hemorheol, 1994; 14: 19-25.
6. BRILEY DP, GIRAUD GD, BEAMER NB, SPEAR EM, GRAUER SE, EDWARDS JM, CLARK WM, SEXTON GJ, COULL BM. Spontaneous echo contrast and hemorheologic abnormalities in cerebrovascular disease. Stroke, 1994; 25: 1564-9.
7. BROWN MM, MARSHALL J. Regulation of cerebral blood flow in response to changes in blood viscosity. Lancet, 1985; 1: 604-9.
8. CAPLAN LR. New therapies for stroke. Arch Neurol, 1997; 54: 1222-4.
9. CAVESTRI R, RADICE L, FERRARINI F, LONGHINI M, LONGHINI E. Influence of erythrocyte aggregability and plasma fibrinogen concentration on CBF with aging. Acta Neurol Scand, 1992; 85: 292-8.
10. COMES L, COSTIN Z, MURESAN A. Observations on isovolemic hemodilution in acute ischemic stroke. Rom J Intern Med, 1996; 34: 43-7.
11. COULL BM, BEAMER N, DE GARNO P, SEXTON G, NORDT F, KNOX R, SEAMAN GVF. Chronic blood hyperviscosity in subjects with acute stroke, transient ischemic attack, and risk factors for stroke. Stroke, 1991; 22: 162-8.
12. DALAKAS MC. High-dose intravenous immunoglobulin and serum viscosity: risk of precipitating thromboembolic events. Neurology, 1994; 44: 223-6.
13. DALAL PM, DALAL KP. Use of channel blockers in acute ischemic cerebrovascular diseases. J Assoc Physicians India, 1995; 43: 394-7.
14. DAVID-DUFILHO M, MONTENY-GARESTIER T, DDEVYNCK MA. Fluorescence measurements of free Ca++ concentration in human erythrocytes using the Ca++ indicator Fura 2. Cell Calcium, 1988; 9: 167-79.
15. DAVIS N, LUCATORTO M. Mannitol revised. J Neurosci Nurs 1994; 26: 170-4.
16. DEL ZOPPO GJ. Thrombolytic therapy in the treatment of stroke. Drugs 1997; 54 (Suppl. 3): 90-8.
17. DHAR P, SESHADRI V, JAYARAMAN G. Heamorheological changes in the patients of myocardial infarction and stroke. Clin Hemorheol, 1995; 5: 715-27.
18. DI PERRI T, FORCONI S, DI LOLLO F, POZZA G. Le sindromi di iperviscosità ematica: fisiologia, patologia e clinica. Il Policlinico Sez Prat, 1983, 90: 576.
19. DI PERRI T, FORCONI S, GUERRINI M, ROSSI C, VERZURI MS, MATERAZZI M, PIERAGALLI D. Blood viscosity in vascular patients. In: "Forum Medici-Haemorheology and vascular diseases", Zyma. 1983: 37.
20. DINTENFASS L. Blood rheology in cardio-vascular diseases. Nature, 1963; 199: 813-5.
21. ERNST E, RESCH KL, MATRAI A, BUHL M, SCHOLOSSER P, PAULSIEN HF. Impaired blood rheology: a risk factor after stroke? J Intern Med, 1991; 229: 457-62.
22. European Carotid Surgery Trialist "Collaborative Group": MCR european carotid surgery trial interim results for symptomatic patients wich severe (70-99% ) or mild (0-29% ) carotid stenosis. Lancet, 1991; 337: 1235-43.
23. FATKIN D, HERBERT E, FENELEY MP. Hematologic correlates of spontaneous echo contrast in patients with atrial fibrillation and implications for thromboembolic risk. Am J Cardiol, 1994; 73: 672-6.
24. FISHER M, MEISELMAN HJ. Hemorheological factors in cerebral ischemia. Stroke, 1991; 22: 1164-9.
25. FLECKENSTEIN-GRUN G, FLECKENSTEIN A. Prevention of cerebrovascular spasm with nimodipine. Stroke, 1990; 21: IV64-71.
26. FORCONI S, BATTISTINI N, GUERRINI M, PASSERO SG for the SIAM Group. A randomized, asa-controlled trial of mesoglycan in secondary prevention after cerebral ischemic events. Cerebrovasc Dis 1995; 5: 334-41.
27. FORCONI S, CAPPELLI R, GUERRINI M, FRIGERIO C, MESSA GL, FURESI L. Fibrinolitic activity of Cyclandelate orally administered in patients suffering from generalized atherosclerotic vasculopathy. A double blind controlled study. J Int Med Res, 1990; 18: 257-65.
28. FORCONI S, GUERRINI M, AGNUSDEI D, LAGHI PASINI F, DI PERRI T. Abnormal blood viscosity in Raynaud's phenomenon. Lancet. 1976; 2: 586.
29. FORCONI S, GUERRINI M, CAPPELLI R, BICCHI M, FONTANI R, TRABALZINI L, VATTIMO A, BERTELLI P, BURRONI L. Effects of treatment with the calcium-entry bloker nimodipine on the cerebral blood flow (spect) and blood viscosity of patients affected by cerebral chronic vascular insufficiency. Clin Hemorheol, 1992; 12: 697-704.
30. FORCONI S, GUERRINI M, CAPPELLI R, SANI P, FURESI L. Rapporti tra endotelio e cellule circolanti a livello microcircolatorio: influenza su coagulazione, fibrinolisi, motilità della parete vascolare ed emoreologia. In: Tesi M. "Microcircolazione 1989", Monduzzi Editore, Bologna 1989: 145-52.
31. FORCONI S, PIERAGALLI D, ACCIAVATTI A, DEL BIGO C, GALIGANI C, RALLI L, GUERRINI M, DI PERRI T. Positive effect of oral buflomedil on exercise-induced haemorheological damage and on claudication distance in peripheral obliterative arterial disease patients. J Int Med Res. 1984; 12: 188.
32. FORCONI S, PIERAGALLI D, ACCIAVATTI A, GALIGANI C, MATERAZZI M, RALLI L, FRANCHI M, LAGHI PASINI F, MESSA G, BIANCIARDI A, RIGATO M, BLARDI P, CAPPELLI R, GUERRINI M, DI PERRI T. Blood Hyperviscosity and peripheral ischemia, the secondary hyperviscosity syndrome of ischemizing vascular diseases. Clin Hemorheol, 1986; 6: 215-27.
33. FORCONI S, PIERAGALLI D, GUERRINI M, DI PERRI T. Hemorheology and peripheral arterial diseases. Clin Hemorheal, 1987; 7: 145-58.
34. FORCONI S, PIERAGALLI D, GUERRINI M, GALIGANI C, CAPPELLI R. Primary and secondary blood hyperviscosity syndromes and syndromes associated with blood hyperviscosity. Drugs, 1987; 33 (Suppl. 2): 19-26.
35. FORCONI S. Regional ischemia and hyperviscosity. Clin Hemorheol, 1988; 8: 321.
36. GALANTE A, SILVESTRINI M, STANZIONE P, PIETROIUSTI A, BALDONI F, DOMENICI B, BERNARDI G. Leucocyte aggregation in acute cerebrovascular disease. Acta Neurol Scand. 1992; 86: 446-9.
37. Generalized efficacy of t-PA for acute stroke. Subgroup analysis of the NINDS t-PA Stroke Trial. Stroke. 1997; 28: 2119-25.
38. GNASSO A, IRACE C, CARALLO C, DE FRANCESCHI MS, MOTTI C, MATTIOLI PL, PUJIA A. In vivo association between low wall shear stress and plaque in subjects with asymmetrical carotid atherosclerosis. Stroke. 1997; 28: 993-8.
39. GODFRAIND T. Calcium entry and calcium entry blocks. Nimodipine report from 4th European Workshop on Clinical Neuropharmacology, Calcium-antagonists and cerebral ischemia. New Pharmacological Results. Pamplona, June 12, 1986: 3.
40. GOSLINGA H, EIJZENBACH V, HEUVELMANS JHA, VAN DER LAAN DE VRIES E, MELIS VMJ, SCHMID-SCHOENBEIN H, BEZEMER PD. Custom-tailored hemodilution with albumin and crystalloids in acute ischemic stroke. Stroke. 1992; 23: 181-8.
41. GOSLINGA H, HEUVELMANS JH, SCHMID-SCHOENBEIN H. Hemo dilution and rehydratation in acute ischemic stroke. A preliminary report on the Amsterdam stroke study. Acta Med Aust, 1991; 18 (Suppl. 1)-41-4.
42. GRENBERG JH, UEMATSU D, ARAKI N, HICKEY WF, REIVICH M. Cytosolic free calcium during cerebral ischemia and the effects of nimodipine on calcium and histologic damage. Stroke. 1990; 21: IV72-7.
43. GUERRINI M, ACCIAVATTI A, MATERAZZI M, ROSSI C, DEL BIGO C, FORCONI S, DI PERRI T. Protective effect of buflomedil against exercise-induced reductions in regional erythrocyte deformability of patients with peripheral arterial disease. J Int Med Res, 1982; 10: 387.
44. GUERRINI M, MAROTTA G, VEDOVINI G, BICCHI M, BOSCHI S, RIELLO F, DE MATTEIS C, LEONCINI F, TURCHETTI V, BERTELLI P, BURRONI L, VATTIMOA, CAPPELLI R, FORCONI S. Valutazioni delle modificazioni sul circolo periferico e sullo stato cognitivo dopo plasmaferesi: osservazioni in un anziano affetto da macroglobulinemia di Waldestron. XXXIX Congresso Nazionale Della Società Italiana di Gerontologia e Geriatria. Siena-Firenze 27-30/11/1994. Atti 1994.
45. HELLMAN RS, TIKOFSKY RS. An overview of the contribution of regional blood flow studies in cerebrovascular disease: is there a role for single photon emission computer tomography? Semin Nucl Med, 1990; 20: 303.
46. HENRY D, O'CONNELL D. Trial of streptokinase in ischaemic stroke. Lancet, 1995; 345: 1053
47. HOGAN M, GYEDDE A, HAKIM HM. Nimodipine binding in focal cerebral ischemia. Stroke, 1990; 21 (Suppl. IV): IV78-IV80.
48. ICHIHARA S, MATSUO H, KITADAI M, HOSOMI N, TSUDA Y. Nimodipine improves brain energy metabolism and blood rheology during ischemia and reperfusion in the gerbil brain. J Neurol Sci, 1996; 144: 84-90.
49. Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study Group. Stroke, 1997; 28: 2109-18.
50. KOWAL P. Hemorheology in cerebral ischemia. Neurol Neurochir Pol, 1996; 30 (Suppl. 2): 7-11.
51. LEES KR. Therapeutic interventions in acute stroke. Br J Clin Pharmacol, 1992; 34: 486-93.
52. LOMBARDINI R, PARNETTI L, MERCURI M, PALAZZETTI D, SAVASTANO V, SCARPONI AM, PALTRICCIA R, CIUFFETTI G. Effects of buflomedil hydrochloride on the rheological properties of the blood in chronic cerebrovascular diseases. Ric Clin Lab, 1989; 19 (Suppl. 1): 117-9.
53. LOWE GDO, LEE AJ, RUMLEY A, PRICE JF, FOWKERS FGR. Blood viscosity and risk of cardiovascular events: the Edinburgh Artery Study. Brit J Haematol, 1997; 96: 168-73.
54. MELARAGNO FILHO R. The importance of clinical hemorheology in the study of cerebral blood flow in normal conditions and in cerebrovascular ischemia. Arq Neuropsiquiatr, 1995; 53 (1): 157-68.
55. MOHAMED AA, MENDOLOW AD, TEASDALE GM, HARPER AM, MCCULLOCH J. Effect of the calcium-antagonist nimodipine on local cerebral blood flow and metabolic coupling. J Cereb Blood Flow Metab 1985; 5: 1.
56. MOREL N, GODFRAIND T. Cerebrovascular effect of calcium antagonists. Ear Neurol, 1990; 110: 992-1000.
57. MORI K, ARAI H, NAKAJIMA K, TAJIMA A, MEDA M. Hemorheological and hemodynamic analysis of hypervolemic hemodilution therapy for cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Stroke, 1995; 26 (9): 1620-6.
58. North American Symptomatic Carotid Endarterectomy Trial (NASCET) Steering Committee: North american symptomatic carotid endarterectomy trial: patient characteristic and progress. Stroke, 1991; 22: 711-20.
59. ORLANDI G, VIAPIANO F, MASSETANI R, FERRARI M, MURRI L. Clinical-instrumental evaluation of the effects of mesoglycan sulphate in chronic vascular encephalopathy. Acta Neurol 1991 ; 13: 255-60.
60. PERANI D, DI PIERO V. Technetium-99m-HM-PAO-SPECT study of regional cerebral perfusion in early Alzheimer's disease. J Nucl Med, 1988; 29: 1507.
61. PRIANIKOVA NA, CHEKNEVA NS, STAKHOVSKAIA LV, DUKHANIN AS. Effect of nimodipine on the intacellular calcium level and platelet aggregation in ischemic stroke patients. Bull Eksp Biol Med. 1996; 121: 317-20.
62. QU SHEN, XU WEI, FAN HONG, GUO SUSHU et al. The study of erythrocytes membrane, ATPase activities, hemorheological changes and their correlation in stroke patients. Clin Hemorheol, 1996; 16(4): 507-13.
63. REID HL, DORMANDY JA, BARNES AJ, LOCK PJ, DORMANDY TL. Impaired red cells deformability in peripheral vascular disease. Lancet, 1976; 1: 666-7.
64. RESCH L, ERNST E, MATRAI A, PAULSEN HF. Fibrinogen and viscosity as risk factors for subsequent cardiovascular event in stroke survivors. Ann Intern Med, 1992; 117: 371-5.
65. SILVESTRINI M, PIETROIUSTI A, MAGRINI A, MATTEIS M, CARTA S, BERNARDI G, GALANTEA. Leukocyte aggregation in patients with a previous cerebral ischemic event. Stroke, 1994; 25: 1390-2.
66. STEEN PA, NEWBERG LA, MILDE JH, MICHEFENFELDER JD. Nimodipine improves cerebral blood flow and neurological recovery after complete cerebral ischemia in the dog. J Cereb Blond Flow Metab, 1983; 3: 1.
67. TAKANO K, YAMAGUCHI T, UCHIDA K. Markers of a hypercoagulable state following acute ischemic stroke. Stroke, 1992; 23: 194-8.
68. TANAHASHI N, GOTOH F, TOMITA M, SHINOHARA T, TERAYAMA Y, MIHARA B, OTHTA K, NARA M. Enhanced erythrocyte aggregabilily in occlusive cerebrovascular disease. Stroke, 1989; 20: 1202-7.
69. TANAHASHI N, TOMITA M, KOBARI M, TAKEDA H, YOKOYAMA M, TAKAO M, FUKUUCHI Y. Platelet activation and erythrocyte aggregation rate in patients with cerebral infarction. Clin Hemorheol, 1996; 16: 497-505.
70. TANAHASHI N, YOKOYAMA M, TAKEDA H, KOBARI M, TOMITA M, FUKUUCHI Y. Pentoxifylline ameliorates postischemic delayed hypoperfusion of the cerebral cortex following cardiac arrest in cats. J Neurol Sci, 1995; 132: 105-9.
71. TEASDALE G, MENDELOW AD, GRAHAM DI, HARPER AM, MCCULLOCH J. Efficacy of nimodipine in cerebral ischemia or hemorrhage. Stroke, 1990; 21: IV123-5.
72. The American Nimodipine Study Group. Clinical trial of nimodipine in acute ischemic stroke. Stroke, 1992; 23: 3-8.
73. TOWART R, KAZDA S. Effects of the calcium-antagonist Nimodipine on isolated cerebral vessels. In: Betz E. Deck K., Hoffmeister F. (Eds.), Nimodipine Pharmacological and Clinical Properties. F.K. Schattauer Verlag, Stuttgart-New York 1985: 207.
74. TSUDA Y, SATOH K, KITADAI M, TAKAHASHI T. Hemorheologic profiles of plasma fibrinogen and blood viscosity from silent to acute and chronic cerebral infarctions. J Neurol Sci, 1997; 147: 49-54.
75. TURCHETTI V, LEONCINI F, DE MATTEIS C, TRABALZINI L, GUERRINI M, FORCONI S. Evaluation of erythrocyte morphology as deformability index in patients suffering from vascular diseases, with or without diabetes mellitus: correlation with blood viscosity and intra-erythrocytic calcium. Clin Hemorheol and Microcirculation, 1998; 18: 141-9.
76. VESEL'SKII ISh, SANIK AV. Microcirculation and the blood rheological properties and their correction in ischemic disorders of the cerebral circulation. Zh Nevropatol Psikhiatr Im S S Korsakova, 1991; 91 (11): 67-70.
77. WALZL B, LECHNER H, VALETITSCH H, WALZL M. Increased cerebral perfusion following reduction of fibrinogen and lipid fractions. Haemostasis, 1995; 25 (3): 137-43.
78. WOLF RE, ALPERIN JB, RITZNMANN SE, LEVIN GW; IgG-K-multiple myelome with hyperviscosity syndrome. Response to plasmapheresis. Arch Intern Med, 1972; 129: 114.
79. WOOD JH, KEE DB. Hemorheology of the cerebral circulation in stroke. Stroke, 1985; 16: 756-72.