A rapid and reliable solid-phase extraction-LC/MS/MS assay for the determination of two novel human leukocyte elastase inhibitors, SYN-1390 and SYN-1396, in rat plasma

Journal of Pharmaceutical and Biomedical Analysis

Volumn 20, Issue 4, 1999, Pages 697-703

  Khan, Jehangir K ^a   Bu, Hai Zhi ^a   Samarendra, Zhong Zuo ^a   Maiti, N ^a   Micetich, Ronald G ^a  

^a NAEJA Pharmaceutical Inc   (Canada)

Author keywords

Human leukocyte elastase inhibitors; Liquid chromatography tandem mass spectrometry; Solid phase extraction; SYN 1390; SYN 1396

Indexed keywords

ELASTASE INHIBITOR; SYN 1390; SYN 1396; UNCLASSIFIED DRUG;

ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; SOLID PHASE EXTRACTION;

ANIMALS; CEPHALOSPORINS; CHROMATOGRAPHY, LIQUID; HUMANS; MASS SPECTROMETRY; RATS; SERPINS;

EID: 0033050972     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(99)00076-X     Document Type: Article

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