Stimulation of μ- and δ-opioid receptors enhances phosphoinositide metabolism in mouse spinal cord: Evidence for subtypes of δ-receptors

European Journal of Neuroscience

Volumn 11, Issue 6, 1999, Pages 2059-2064

  Sánchez Blázquez, Pilar ^a   Rodríguez Díaz, Marta ^a   Frejo, María Teresa ^a,b   Garzón, Javier ^a  

^a INSTITUTO CAJAL   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

opioid receptor subtypes; opioid receptors; Inositol phosphates; Pertussis toxin sensitive G proteins; Selective antagonists; Spinal cord

Indexed keywords

7 BENZYLIDENENALTREXONE; DELTA OPIATE RECEPTOR; DELTORPHIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; MESYLIC ACID; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; NALTRIBEN; NALTRINDOLE; OPIATE AGONIST; OPIATE ANTAGONIST; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITIDE; RECEPTOR SUBTYPE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANIMALS; INOSITOL PHOSPHATES; ISOMERISM; MALE; MICE; MICE, INBRED STRAINS; NARCOTIC ANTAGONISTS; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOLS; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; SPINAL CORD; VIRULENCE FACTORS, BORDETELLA;

EID: 0033046357     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00624.x     Document Type: Article

References (26)

1. Arvidsson, U., Dado, R.J., Riedl, M., Lee, J.-H., Law, P.-Y., Loh, H.H., Elde, R. & Wessendorf, M.W. (1995) δ-opioid receptor immunoreactivity: distribution in brainstem and spinal cord and relationship to biogenic amines and enkephalin. J. Neurosci., 15, 1215-1235.
2. Berridge, M.J., Downes, C.P. & Hanley, M.E. (1982) Lithium amplifies agonist-dependent phosphatidylinositol. responses in brain and salivary glands. Biochem. J., 206, 587-595.
3. Chen, L. & Huang, L.-Y.M. (1991) Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a μ opioid. Neuron, 7, 319-326.
4. Childers, S.R. (1991) Opioid receptor coupled second messenger systems. Life Sci., 48, 1991-2003.
5. Claro, E., Garcia, A. & Picatoste, F. (1987) Histamine-stimulated phosphoinositide hydrolysis in developing rat brain. Mol. Pharmacol., 32, 384-390.
6. Cotton, R., Giles, M.G., Miller, L., Shaw, J.S. & Timm, D. (1984) ICI174,864 a highly selective antagonist for the opioid delta receptor. Eur. J. PharmacoL, 97, 331-332.
7. Dunbar, S. & Yaksh, T.L. (1996) Effect of spinal infusion of L-NAME, a nitric oxide synthase inhibitor on spinal tolerance and dependence induced by chronic intrathecal morphine in the rat. Neurosci. Lett., 207, 33-36.
8. Elliot, K., Minami, N., Kolesnikov, Y.A., Pasternak, G.W. & Inturrisi, C.E. (1994) The NMDA receptor antagonists LY274614 and MK-801, and the nitric oxide synthase inhibitor NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to the kappa opioids. Pain, 56, 69-75.
9. Fang, L., Knapp, R.J., Horvath, R., Matsunaga, T.O., Haaseth, R.C., Hruby, V.J., Porreca. F. & Yamamura, H.I. (1994) Characterization of [3H]naltrindole binding to delta opioid receptors in mouse brain and mouse vas deferens: Evidence for delta opioid receptor heterogeneity. J. Pharmacol. Exp. Ther., 268, 836-846.
10. García-Ladona, F.J., Claro, E., Garcia, A. & Picatoste, F. (1993) Denervation hypersensitivity of histamine HI-receptors in rat brain cortex. Neuroreport, 4, 691-694.
11. Garzón, J., Sánchez-Blázquez, P., Gerhart, J., Loh, H.H. & Lee, N.M. (1984) Dynorphin A: inhibitory effect on other opiate ligand bindings in the mouse brain. Biochem. Pharmacol., 33, 2609-2614.
12. Garzón, J., García-Espana, A. & Sanchez-Blázquez, P. (1997a) Opioids binding mu and delta receptors exhibit diverse efficacy in the activation of Gi2 and Gx/z transducer proteins in mouse periaqueductal gray matter. J. Pharmacol. Exp. Ther., 281, 549-557.
13. Garzón, J., Martínez-Peña, Y. & Sanchez-Blázquez, P. (1997b) Gx/z is regulated by mu but not delta opioid receptors in the stimulation of the low Am GTPase activity in mouse periaqueductal grey matter. Eur. J. Neurosci., 9, 1194-1200.
14. Glaum, S.R., Miller, R.J. & Hammond, D.L. (1994) Inhibitory actions of δ1-δ2- and μ-opioid receptor agonists on excitatory transmission in lamina II neurons of adult rat spinal cord. J. Neurosci., 14, 4965-1971.
15. Gouarderes, C., Cros, J. & Quirion, R. (1985) Autoradiographic localization of, δ and K opioid receptors binding sites in rat a guinea pig spinal cord. Neuropeptides, 6, 331-342.
16. Höllt, V., Sánchez-Blázquez, P. & Garzón, J. (1985) Multiple opioid ligands and receptors in the control of nociception. Phil. Trans. R. Soc. Lond. B, 308, 299-310.
17. Jin, W., Lee, N.M., Loh, H.H. & Thayer, S.A. (1994) Opioids mobilize calcium from inositol 1,4,5-triphosphate-sensitive Stores in NG 108-15 cells. J. Neurosci., 14, 1920-1929.
18. Kolesnikov, Y.A., Maccechini, M.-L. & Pasternak, G.W. (1994) 1-Aminocyclopropane carboxylic acid (ACPC) prevents mu and delta opioid tolerance. Life Sci., 55, 1393-1398.
19. Kolesnikov, Y.A., Pan, Y.-X., Babey, A.-M., Jain, S., Wilson, R. & Pasternak, G.W. (1997) Functionally differentiating two nNOS isoforms through antisense mapping: Evidence for opposing NO actions on morphine analgesia and tolerance. Proc. Natl Acad. Sci. USA, 94, 8220-8225.
20. Kolesnikov, Y.A., Jain, S., Wilson, R. & Pasternak, G.W. (1998) Lack of morphine and enkephalin tolerance in 129/SvE mice: Evidence for a NMDA receptor defect. J. Phannacol. Exp. Ther., 284, 455-459.
21. Laugwitz, K.-L., Offermanns, S., Spicher, K. & Schultz, G. (1993) μ and δ opioid receptors differentially couple to G proteins subtypes in membranes of human neuroblastoma SH-SY5Y cells. Neuron, 1, 233-242.
22. Lufty, K., Shen, K.-Z., Kwon, I.-S., Cai, S.X., Woodward, R.M., Keana, J.F.W. & Weber, E. (1995) Blockade of morphine tolerance by ACEA-13328 a novel NMDA receptor/glycine site antagonist. Eur. J. Pharmacol., 273, 187-189.
23. Manning, B.H., Mao, J.R., Frenk, H., Price, D.D. & Mayer, D.J. (1996) Continuous co-administration of dextromethorphan or MK-801 with morphine: Attenuation of morphine dependence and naloxone reversible attenuation of morphine tolerance. Pain, 67, 79-88.
24. 2]deltorphin II in mice: Evidence for delta receptor subtypes. J. Pharmacol. Exp. Ther., 260, 518-525.
25. Mattia, A., Farmer, S.C., Takemori; A.E., Sultana, M., Portoghese, P.S., Mosberg, H.I., Bowen, W.D. & Porreca, F. (1992) Spinal opioid delta antinociception in the mouse: Mediation by a 5′-NTII sensitive delta receptor subtype. J. Pharmacol. Exp. Ther., 263, 264-275.
26. Miyamae, T., Fukushima, N., Misu, Y. & Ueda, H. (1993) δ opioid receptor mediates phospholipase C activation via Gi in Xenopus oocytes. FEBS Lett., 333, 311-314.