The survival of monolayers of cells growing in clusters irradiated by 211At appended to the cell surfaces

Radiation Research

Volumn 151, Issue 6, 1999, Pages 750-753

  Charlton, D E ^a  

^a Gina Cody School of Engineering and Computer Science   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ASTATINE 211; MONOCLONAL ANTIBODY; POLONIUM; RADIOISOTOPE;

ALPHA RADIATION; ARTICLE; COMPUTER MODEL; HALF LIFE TIME; HUMAN; HUMAN CELL; MELANOMA CELL; MONOLAYER CULTURE; PARTICLE RADIATION; PRIORITY JOURNAL; RADIATION EXPOSURE;

ALPHA PARTICLES; ASTATINE; CELL SURVIVAL; HUMANS; LINEAR ENERGY TRANSFER; MELANOMA; TUMOR CELLS, CULTURED;

EID: 0033044903     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3580215     Document Type: Article

References (5)

1. R. H. Larsen, G. Akabani, P. Welsh and M. R. Zalutsky, The cytotoxicity and microdosimetry of astatine-211-labeled chimeric monoclonal antibodies in human glioma and melanoma cells in vitro. Radiat. Res. 149, 155-162 (1998).
2. J. F. Ziegler, SRIM96, The Transport of Ions in Matter. IBM Research, Yorktown, NY, 1996.
3. D. E. Charlton and M. S. Turner, Use of chord lengths through the nucleus to simulate the survival of mammalian cells exposed to high LET α-radiation. Int. J. Radiat. Biol. 69, 213-217 (1996).
4. M. R. Raju, Y. Eisen, S. Carpenter and W. C. Inkret, Radiobiology of α particles. III. Cell inactivation by α-particle traversals of the cell nucleus. Radiat. Res. 127, 204-209 (1991).
5. M. R. Raju, Y. Eisen, S. Carpenter, K. Jarret and W. F. Harvey, Radiobiology of alpha particles. IV. Cell inactivation by alpha particles of energies 0.4-3.5 MeV. Radiat. Res. 133, 289-296 (1993).