Fatal familial insomnia: Clinical features and molecular genetics

Journal of Sleep Research

Volumn 8, Issue SUPPL. 1, 1999, Pages 23-29

  Cortelli, Pietro ^a   Gambetti, Pierluigi ^b   Montagna, Pasquale ^a   Lugaresi, Elio ^a,c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Dysautonomia; Heterozygotes; Homozygotes; Limbic thalamus; Sleep loss; Thalamic degeneration

Indexed keywords

METHIONINE; PRION PROTEIN; VALINE;

ATAXIA; ATTENTION; AUTOSOMAL DOMINANT INHERITANCE; BRAIN CORTEX; BRAIN DEGENERATION; CINGULATE GYRUS; CIRCADIAN RHYTHM; CLINICAL FEATURE; DISEASE COURSE; DYSARTHRIA; DYSAUTONOMIA; FATAL FAMILIAL INSOMNIA; HETEROZYGOTE; HOMEOSTASIS; HOMOZYGOTE; HUMAN; INSOMNIA; MISSENSE MUTATION; MOLECULAR GENETICS; ORBITAL CORTEX; PRIORITY JOURNAL; REVIEW; SLEEP WAKING CYCLE; THALAMUS; THALAMUS NUCLEUS; AUTONOMIC DYSFUNCTION; BRAIN ATROPHY; HYPERACTIVITY; NEUROPATHOLOGY; PRION DISEASE; APOPTOSIS; ARTICLE; BLOOD PRESSURE; CODON; GENETIC POLYMORPHISM; GENETICS; HEART RATE; MIDDLE AGED; NERVE DEGENERATION; PATHOLOGY; PEDIGREE; PERSISTENT VEGETATIVE STATE; POINT MUTATION; PREVALENCE; SLEEP DISORDER; TIME;

APOPTOSIS; BLOOD PRESSURE; CODON; DYSAUTONOMIA, FAMILIAL; HEART RATE; HUMANS; MIDDLE AGED; NERVE DEGENERATION; PEDIGREE; PERSISTENT VEGETATIVE STATE; POINT MUTATION; POLYMORPHISM, GENETIC; PREVALENCE; PRION DISEASES; SLEEP DISORDERS; THALAMUS; TIME FACTORS;

EID: 0033040530     PISSN: 09621105     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2869.1999.00005.x     Document Type: Review

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