Inhalation toxicity and genotoxicity of hydrochlorofluorocarbon (HCFC)-225ca and HCFC-225cb

Journal of Applied Toxicology

Volumn 19, Issue 2, 1999, Pages 101-112

  Brock, William J ^a   Shin Ya, Seiji ^b   Rusch, George M ^c   Hardy, Colin J ^d   Trochimowicz, Henry J ^a  

^a DUPONT COMPANY   (United States)

^b ASAHI GLASS CO LTD   (Japan)

^c HONEYWELL   (United States)

^d HUNTINGDON LIFE SCIENCES   (United Kingdom)

Author keywords

Genotoxicity; HCFC 225ca; HCFC 225cb; Hydrochlorofluorocarbons; Inhalation toxicity

Indexed keywords

CHLOROFLUOROHYDROCARBON; CLASTOGEN; CYTOCHROME P450; IRRITANT AGENT;

AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL VACUOLE; CHINESE HAMSTER; CHROMOSOME ABERRATION; CONTROLLED STUDY; DOG; EXPOSURE; FATTY ACID OXIDATION; FEMALE; GENOTOXICITY; HEART ARRHYTHMIA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INHALATION; INTRACELLULAR FLUID; ISOMER; LETHAL DOSE; LIVER CELL; LIVER HYPERTROPHY; LIVER SINUSOID; LIVER WEIGHT; LUNG ALVEOLUS CELL; LYMPHOCYTE; MALE; MITOSIS RATE; MOTOR ACTIVITY; MUTAGEN TESTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; SEX DIFFERENCE; TOXICITY TESTING; UNSCHEDULED DNA SYNTHESIS;

ADMINISTRATION, INHALATION; ANIMALS; CELLS, CULTURED; CHLOROFLUOROCARBONS; CHOLESTEROL; CRICETINAE; CRICETULUS; CYTOCHROME P-450 ENZYME SYSTEM; DNA REPLICATION; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HAZARDOUS SUBSTANCES; HEART; HUMANS; LETHAL DOSE 50; LIVER; LUNG; LYMPHOCYTES; MALE; MUTAGENICITY TESTS; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; TRIGLYCERIDES;

ANIMALIA; CANIS FAMILIARIS; CRICETINAE; CRICETULUS GRISEUS;

EID: 0033039620     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1263(199903/04)19:2<101::AID-JAT546>3.0.CO;2-R     Document Type: Article

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