-
1
-
-
0028577327
-
Dihydropyrimidine dehydrogenase (DPD) and clinical pharmacology of 5-fluorouracil (review)
-
Milano G, Etienne M-C: Dihydropyrimidine dehydrogenase (DPD) and clinical pharmacology of 5-fluorouracil (review). Anti-cancer Res 14:2295-2298, 1994.
-
(1994)
Anti-cancer Res
, vol.14
, pp. 2295-2298
-
-
Milano, G.1
Etienne, M.-C.2
-
2
-
-
0027426408
-
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy
-
Lu Z, Zhang R, Diasio RB: Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy. Cancer Res 53:5433-5438, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 5433-5438
-
-
Lu, Z.1
Zhang, R.2
Diasio, R.B.3
-
3
-
-
0020451764
-
Rapid catabolism of 5-fluorouracil in freshly isolated rat hepatocytes as analyzed by high performance liquid chromatography
-
Sommadossi J-P, Gerwirtz DA, Diasio RB, et al: Rapid catabolism of 5-fluorouracil in freshly isolated rat hepatocytes as analyzed by high performance liquid chromatography. J Biol Chem 257:8171-8176, 1982.
-
(1982)
J Biol Chem
, vol.257
, pp. 8171-8176
-
-
Sommadossi, J.-P.1
Gerwirtz, D.A.2
Diasio, R.B.3
-
4
-
-
0026753035
-
Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients
-
Fleming R, Milano G, Thyss A, et al: Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients. Cancer Res 52:2899-2902, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 2899-2902
-
-
Fleming, R.1
Milano, G.2
Thyss, A.3
-
5
-
-
0022263834
-
Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity
-
Tuchman M, Stoeckeler JS, Kiang DT, et al: Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity. N Engl J Med 313:245-249, 1985.
-
(1985)
N Engl J Med
, vol.313
, pp. 245-249
-
-
Tuchman, M.1
Stoeckeler, J.S.2
Kiang, D.T.3
-
7
-
-
0001500798
-
Acute cerebellar syndrome secondary to 5-fluorouracil therapy
-
Riebl J-L, Brown WJ: Acute cerebellar syndrome secondary to 5-fluorouracil therapy. Neurology 961-967, 1964.
-
(1964)
Neurology
, pp. 961-967
-
-
Riebl, J.-L.1
Brown, W.J.2
-
8
-
-
0019475570
-
"Organic brain syndrome" secondary to 5-fluorouracil toxicity
-
Lynch HT, Droszcz CP, Albano WA, et al: "Organic brain syndrome" secondary to 5-fluorouracil toxicity. Dis Colon Rectum 24:130-131, 1981.
-
(1981)
Dis Colon Rectum
, vol.24
, pp. 130-131
-
-
Lynch, H.T.1
Droszcz, C.P.2
Albano, W.A.3
-
9
-
-
0026602484
-
Multifocal inflammatory leukoencephalopathy with 5-fluorouracil and levamisole
-
Hook CC, Kimmel DW, Kvols LK, et al: Multifocal inflammatory leukoencephalopathy with 5-fluorouracil and levamisole. Ann Neural 31:262-267, 1992.
-
(1992)
Ann Neural
, vol.31
, pp. 262-267
-
-
Hook, C.C.1
Kimmel, D.W.2
Kvols, L.K.3
-
10
-
-
0028098810
-
Cerebral demyelination with 5-fluorouracil and levamisole
-
Fassas AB-T, Gattani AM, Morgello S: Cerebral demyelination with 5-fluorouracil and levamisole. Cancer Invest 12:379-383, 1994.
-
(1994)
Cancer Invest
, vol.12
, pp. 379-383
-
-
Fassas, A.B.-T.1
Gattani, A.M.2
Morgello, S.3
-
11
-
-
9044246668
-
Severe neurotoxicity following 5-fluorouracil-based chemotherapy in a patient with dihydropyrimidine dehydrogenase deficiency
-
Takimoto CH, Lu Z, Zhang R, et al: Severe neurotoxicity following 5-fluorouracil-based chemotherapy in a patient with dihydropyrimidine dehydrogenase deficiency. Clin Cancer Res 2:477-481, 1996.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 477-481
-
-
Takimoto, C.H.1
Lu, Z.2
Zhang, R.3
-
12
-
-
0027534425
-
Dihydropyrimidine dehydrogenase activity in cancer patients
-
Fleming RA, Milano GA, Gaspard MH, et al: Dihydropyrimidine dehydrogenase activity in cancer patients. Eur J Cancer 29A:740-744, 1993.
-
(1993)
Eur J Cancer
, vol.29 A
, pp. 740-744
-
-
Fleming, R.A.1
Milano, G.A.2
Gaspard, M.H.3
-
13
-
-
0015641008
-
Kinetics of entry and distribution of 5-fluorouracil in cerebrospinal fluid and brain following intravenous injection in a primate
-
Bourke RS, West CR, Chheda G, et al: Kinetics of entry and distribution of 5-fluorouracil in cerebrospinal fluid and brain following intravenous injection in a primate. Cancer Res 33:1735-1746, 1973.
-
(1973)
Cancer Res
, vol.33
, pp. 1735-1746
-
-
Bourke, R.S.1
West, C.R.2
Chheda, G.3
-
14
-
-
0029619542
-
Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities
-
Stephan F, Etienne M-C, Wallahs C, et al: Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities. Am J Med 99:685-688, 1995.
-
(1995)
Am J Med
, vol.99
, pp. 685-688
-
-
Stephan, F.1
Etienne, M.-C.2
Wallahs, C.3
-
15
-
-
0014631050
-
Biochemical basis of the acute cerebellar syndrome in 5-fluorouracil chemotherapy
-
Chainage H, Panel A: Biochemical basis of the acute cerebellar syndrome in 5-fluorouracil chemotherapy. Trans Am Neurol Assoc 94:290-292, 1969.
-
(1969)
Trans Am Neurol Assoc
, vol.94
, pp. 290-292
-
-
Chainage, H.1
Panel, A.2
-
16
-
-
0025990479
-
Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency
-
Harris BE, Carpenter JT, Diasio RB: Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. Cancer 68:499-501, 1991.
-
(1991)
Cancer
, vol.68
, pp. 499-501
-
-
Harris, B.E.1
Carpenter, J.T.2
Diasio, R.B.3
-
17
-
-
0028006858
-
Population study of dihydropyrimidine dehydrogenase in cancer patients
-
Etienne MC, Lagrange JL, Dassonville O, et al: Population study of dihydropyrimidine dehydrogenase in cancer patients. J Clin Oncol 12:2248-2253, 1994.
-
(1994)
J Clin Oncol
, vol.12
, pp. 2248-2253
-
-
Etienne, M.C.1
Lagrange, J.L.2
Dassonville, O.3
-
18
-
-
0028559551
-
Potential importance of dihydropyrimidine dehydrogenase (DPD) in cancer chemotherapy
-
Milano G, Etienne M-C: Potential importance of dihydropyrimidine dehydrogenase (DPD) in cancer chemotherapy. Pharmacogen 4:301-306, 1994.
-
(1994)
Pharmacogen
, vol.4
, pp. 301-306
-
-
Milano, G.1
Etienne, M.-C.2
-
19
-
-
0025774575
-
Inhibition of fluoropyrimidine catabolism by benzyloxybenzyluracil. Possible relevance to regional chemotherapy
-
Daher GC, Naquib FN, el-Kouni MH, et al: Inhibition of fluoropyrimidine catabolism by benzyloxybenzyluracil. Possible relevance to regional chemotherapy. Biochem Pharmacol 41:1887-1893, 1991.
-
(1991)
Biochem Pharmacol
, vol.41
, pp. 1887-1893
-
-
Daher, G.C.1
Naquib, F.N.2
El-Kouni, M.H.3
-
20
-
-
0028920324
-
Attenuation of the antitumor activity of 5-fluorouracil by (R)-5-fluoro-5,6-dihydrouracil
-
Spector T, Cao S, Rustum YM, et al: Attenuation of the antitumor activity of 5-fluorouracil by (R)-5-fluoro-5,6-dihydrouracil. Cancer Res 55:1239-1241, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1239-1241
-
-
Spector, T.1
Cao, S.2
Rustum, Y.M.3
-
21
-
-
0027489763
-
5-ethynyluracil (776C85): A potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil
-
Baccanari DP, Davis ST, Knick VC, et al: 5-Ethynyluracil (776C85): a potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil. Proc Natl Acad Sci USA 90: 11064-11068, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11064-11068
-
-
Baccanari, D.P.1
Davis, S.T.2
Knick, V.C.3
-
22
-
-
0028281781
-
5-ethynyluracil (776C85): Modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma
-
Cao S, Rustum YM, Spector T: 5-Ethynyluracil (776C85): modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma. Cancer Res 54:1507-1510, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 1507-1510
-
-
Cao, S.1
Rustum, Y.M.2
Spector, T.3
-
23
-
-
0344970611
-
The dihydropyrimidine dehydrogenase inhibitor 776C85: Making oral 5-fluorouracil practical and modifying its therapeutic index
-
Rowinsky EK, Baker SD: The dihydropyrimidine dehydrogenase inhibitor 776C85: making oral 5-fluorouracil practical and modifying its therapeutic index. Cancer Invest 15(Suppl 1):16-18, 1996.
-
(1996)
Cancer Invest
, vol.15
, Issue.SUPPL. 1
, pp. 16-18
-
-
Rowinsky, E.K.1
Baker, S.D.2
-
24
-
-
0027426408
-
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy
-
Lu Z, Zhang R, Diasio RB: Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy. Cancer Res 53:5433-5438.
-
Cancer Res
, vol.53
, pp. 5433-5438
-
-
Lu, Z.1
Zhang, R.2
Diasio, R.B.3
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