Genetic analysis of susceptibility to infection with Ascaris lumbricoides

American Journal of Tropical Medicine and Hygiene

Volumn 60, Issue 6, 1999, Pages 921-926

  Williams Blangero, Sarah ^a   Subedi, Janardan ^b   Upadhayay, Ram Prasad ^c,d   Manral, Deepak B ^c,d   Rai, Dev R ^c,d   Jha, Bharat ^c,d   Robinson, Edward S ^a   Blangero, John ^a  

^a SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^b MIAMI UNIVERSITY   (United States)

^c TRIBHUVAN UNIVERSITY   (Nepal)

^d Jiri Helminth Project Nepal   (Nepal)

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE;

ARTICLE; ASCARIS LUMBRICOIDES; DISEASE SEVERITY; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; HELMINTHIASIS; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; NEPAL; NONHUMAN; PEDIGREE;

EID: 0033034480     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.1999.60.921     Document Type: Article

References (53)

1. Pawlowski ZS, 1990. Ascariasis. Warren KS, Mahmoud AAF, eds. Tropical and Geographical Medicine. New York: McGraw-Hill, 369-378.
2. WHO, 1987. Prevention and control of intestinal parasitic infections. World Health Organ Tech Rep Ser 749.
3. Tanowitz HB, Weiss LM, Wittner M, 1994. Diagnosis and treatment of common intestinal helminths. II. Common intestinal nematodes. Gastroenterologist 2: 39-49.
4. Mpairwe JB, 1991. Complications of Ascaris lumbricoides infection: case reports from southwestern Uganda. J Helminthol 65: 286-288.
5. Crompton DWT, Neisham M, Pawlowski ZS, 1985. Ascariasis and Its Public Health Significance. London: Taylor and Francis.
6. Savioli L, Bundy D, Tomkins A, 1992. Intestinal parasitic infections: a soluble public health problem. Trans R Soc Trop Med Hyg 86: 353-354.
7. Crompton DWT 1992. Ascariasis and childhood malnutrition. Trans R Soc Trop Med Hyg 86: 577-579.
8. Gupta MC, 1990. Effect of ascariasis upon nutritional status of children. J Trop Pediatr 36: 189-191.
9. Stephenson LS, 1987. The Impact of Helminth Infections on Human Nutrition. London: Taylor and Francis.
10. Thein-Hlaing, Than-Saw, Myat-Lay-Kyin, 1991. The impact of three monthly age-targeted chemotherapy in Okpo village, rural Burma. Trans R Soc Trop Med Hyg 85: 519-522.
11. Chai J-Y, Seo B-S, Lee S-H, 1983. Epidemiological studies on Ascaris lumbricoides reinfection in rural communities in Korea. II. Age-specific reinfection rates and familial aggregation of the reinfected cases. Korean J Parasitol 21: 142-149.
12. Williams D, Burke G, Hendley JO, 1974. Ascariasis: a family disease. J Pediatr 84: 853-854.
13. Forrester JE, Scott ME, Bundy DAP, Golden MHN, 1988. Clustering of Ascaris lumbricoides and Trichuris trichiura infections within households. Trans R Soc Trop Med Hyg 82: 282-288.
14. Wakelin D, 1985. Genetic control of immunity to helminth infections. Parasitol Today 1: 17-23.
15. Wakelin D, 1986. Genetic and other constraints on resistance to infection with gastrointestinal nematodes. Trans R Soc Trop Med Hyg 80: 742-747.
16. Wakelin D, 1991. Immunity and genetics: their relation to control of parasitic oonoses. Parassitologia 33: 61-66.
17. Conchedda M, Ferretti G 1984. Susceptibility of different strains of mice to various levels of infection with the eggs of Taenia taeniaeformis. Int J Parasitol 14: 541-546.
18. Mitchell GF, Rajasekariah GR, Rickard MD, 1980. A mechanism to account for mouse strain resistance to the larval cestode Taenia taeniaeformis. Immunology 39: 481-489.
19. Lamas DA, Mitchell LA, Wakelin D, 1989. Genetic control of eosinophilia. Analysis of production and response to eosinophil-differentiating factor in strains of mice infected with Trichinella spiralis. Clin Exp Immunol 77: 137-143.
20. Timothy LM, Behnke JM, 1997. Necatur americanus in inbred mice: evidence in support of genetically determined differences in the cellular immune response to a primary infection. Parasitology 114: 53-63.
21. Bolas-Fernandez F, Wakelin D, 1989. Infectivity of Trichinella isolates in mice is determined by host immune responsiveness. Parasitology 99: 83-88.
22. Dargie JD, 1982. The influence of genetic factors on the resistance of ruminants to gastrointestinal nematode and trypanosome infections. Owen DF, ed. Animal Models in Parasitology. New York: MacMillan, 17-51.
23. Barlow R, Piper LR, 1985. Genetic analyses of nematode egg counts in Hereford and crossbred Hereford cattle in the sub-tropics of New South Wales. Livestock Production Sci 12: 79-84.
24. Mackinnon MH, Meyer K, Hetzel DJS, 1991 Genetic variation and covariation for growth, parasite resistance, and heat tolerance in tropical cattle. Livestock Production Sci 27: 105-122.
25. Forrester JE, Scott ME, Bundy DAP, Golden MHN, 1990. Predisposition of individuals and families in Mexico to heavy infection with Ascaris lumbricoides and Trichuris trichiura. Trans R Soc Trop Med Hyg 84: 272-276.
26. Chan L, Bundy DA, Kan SP, 1994. Genetic relatedness as a determinant of predisposition to Ascaris lumbricoides and Trichuris Trichiura infection. Parasitology 108: 77-80.
27. Conway DJ, Hall A, Anwar KS, Rahman MI, Bundy DA, 1995. Household aggregation of Strongyloides stercoralis infection in Bangladesh. Trans K Soc Trop Med Hyg 89: 258-261.
28. Holland CV, Crompton DW, Asaolu SO, Crichton WB, Torimiro SE, Walters DE, 1992. A possible genetic factor influencing protection from infection with Ascaris lumbricoides in Nigerian children. J Parasitol 78: 915-916.
29. Secor WE, del Corral H, dos Reis MG, Ramos EA, Zimon AE, Matos EP, Reis EA, do Carmo TM, Hirayama K, David RA, David JR, Harn Jr DA, 1996. Association of hepatosplenic schistosomiasis with HLA-DQB1*0201. J Infect Dis 174: 1131-1135.
30. Smith T, Bhatia K, Branish G, Ashford RW, 1991. Host genetic factors do not account for variation in parasite loads in Strongyloides fuelleborni kellyi. Ann Trop Med Parasitol 5: 533-537.
31. Williams-Blangero S, Blangero J, Bradley M, 1997. Quantitative genetic analysis of susceptibility to hookworm infection in a population from rural Zimbabwe. Hum Biol 69: 201-208.
32. Abel L, Demanais F, Prata A, Souza AE, Dessain A, 1991. Evidence for the segregation of a major gene in human susceptibility/resistance to infection by Schistosoma mansoni. Am J Hum Genet 48: 959-970.
33. Marquet S, Abel L, Hillaire D, Dessain H, Kahl J, Feingold J, Weissenback J, Dessain AJ, 1996. Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nat Genet 14: 181-184.
34. Williams-Blangero S, 1990. Population structure of the Jirels: patterns of mate choice. Am J Phys Anthropol 82: 61-72.
35. Blangero J, 1988. The selective neutrality of dermatoglyphic variation. Int J Anthropol 3: 289-299.
36. Blangero J, 1990. Population structure analysis using polygenic traits: estimation of migration matrices. Hum Biol 62: 27-48.
37. Relethford JH, Blangero J, 1990. Detection of differential gene flow from patterns of quantitative variation. Hum Biol 62: 5-25.
38. Williams-Blangero S, 1989. Clan-structured migration and phenotypic differentiation in the Jirels of Nepal. Hum Biol 61: 143-157.
39. Williams-Blangero S, 1989. Phenotypic consequences of non-random migration in the Jirels of Nepal. Am J Phys Anthropol 80: 115-126.
40. Williams-Blangero S, Blangero J, 1989. Anthropometric variation and the genetic structure of the Jirels of Nepal. Hum Biol 61: 1-12.
41. Williams-Blangero S, Blangero J, 1990. Effects of population structure on within group variation in the Jirels of Nepal. Hum Biol 62: 131-146.
42. Williams-Blangero S, Blangero J, 1991. Skin color variation in eastern Nepal. Am J Phys Anthropol 85: 281-292.
43. Williams-Blangero S, Blangero J, 1992. Quantitative genetic analysis of skin reflectance: a multivariate approach. Hum Biol 64: 35-49.
44. Williams-Blangero S, Blangero J, Robinson ES, Adhikhari BN, Upreti RP, Pyakurel S, 1993. Helminthic infections in Jiri, Nepal: analysis of age and ethnic group effects. J Inst Med 15: 210-216.
45. Williams-Blangero S, Subedi J, Upadhayay RP, Manral DB, Khadka K, Jirel S, Robinson ES, Blangero J, 1998. Attitudes towards helminthic infection in the Jirel population of eastern Nepal. Soc Sci Med 47: 371-379.
46. Dyke B, 1989. PEDSYS: A Pedigree Data Management System. Users Manual. PGL Technical Report No, 2. San Antonio, TX: Southwest Foundation for Biomedical Research.
47. Pene P, Mojon M, Garin JP, Coulaud JP, Rossignol JF, 1982. Albendazole: a new broad spectrum anthelminthic. Am J Trop Med Hyg 31: 263-266.
48. Rossignol JF, Maisonneuve H, 1983. Albendazole: placebo-controlled study in 870 patients with intestinal helminthiasis. Trans R Soc Trop Med Hyg 77: 707-711.
49. de Silva N, Guyatt H, Bundy D, 1997. Amhelmintics: a comparative review of their clinical pharmacology. Drugs 53: 769-788.
50. Blangero J, Almasy L, 1997. Multipoint oligogenic linkage analysis of quantitative traits. Genet Epidemiol 14: 959-964.
51. Almasy L, Blangero J, 1998. Multipoint quantitative trait linkage analysis in general pedigrees. Am J Human Genet 62: 1198-1211.
52. Lange K, Weeks D, Boehnke M, 1988. Programs for pedigree analysis: Mendel, Fisher and dGene. Genet Epidemiol 5: 471-472.
53. Gelbert LM, Gregg RE, 1997. Will genetics really revolutionize the drug discovery process? Curr Opin Biotechnol 8: 669-674.