Relative localization of angiotensin-converting enzyme, chymase and angiotensin II in human coronary atherosclerotic lesions

Journal of Hypertension

Volumn 17, Issue 4, 1999, Pages 547-553

  Ohishi, Mitsuru ^a   Ueda, Makiko ^b   Rakugi, Hiromi ^a   Naruko, Takahiko ^c   Kojima, Akiko ^d   Okamura, Atsunori ^a   Higaki, Jitsuo ^a   Ogihara, Toshio ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c OSAKA CITY GENERAL HOSPITAL   (Japan)

^d Osaka Prefecture University   (Japan)

Author keywords

Angiotensin; Atherosclerosis; Chymase; Human; Immunocytochemistry

Indexed keywords

ANGIOTENSIN; CHYMASE; DIPEPTIDYL CARBOXYPEPTIDASE;

AGED; ARTERY INTIMA; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROSCLEROTIC PLAQUE; AUTOPSY; CELL DAMAGE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CORONARY ARTERY ATHEROSCLEROSIS; CYTOSOL; ENZYME ACTIVATION; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MALE; MAST CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; SCHOOL CHILD; TISSUE CHARACTERIZATION;

EID: 0033033230     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199917040-00013     Document Type: Article

References (30)

1. 1 Campbell JH, Fennessy P, Campbell GR. Effect of perindopril on the development of atherosclerosis in the cholesterol-fed rabbit. Clin Exp Pharmacol Physiol 1992; 19 (suppl):13-17.
2. 2 Dzau VJ. Local expression and pathophysiological role of renin-angiotensin in the blood vessels and heart. Basic Res Cardiol 1993; 1:1-14.
3. 3 Dzau VJ. Cell biology and genetics of angiotensin in cardiovascular disease. J Hypertens 1994; 12 (suppl 4):S3-S10.
4. 4 Pepine CJ. Angiotensin converting enzyme inhibition and coronary artery disease. J Hypertens 1994; 12 (suppl 4):S65-S71.
5. 5 Yusuf S, Pepine CJ, Garces C, Pouleur H, Salem D, Kostis J, et al. Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions. Lancet 1992; 340:1173-1178.
6. 6 Pfeffer MA, Braunwald E, Moye LA, Basta L, Brown EJ Jr, Cuddy TE, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 1992; 327:669-677.
7. 7 Mancini GB, Henry GC, Macaya C, O'Neill BJ, Pucillo AL, Carere RG, et al. Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study. Circulation 1996; 94:258-265.
8. 8 Leite R, Salgado MC. Increased vascular formation of angiotensin II in one-kidney, one clip hypertension. Hypertension 1992; 19:575-581.
9. 9 Rakugi H, Wang DS, Dzau VJ, Pratt RE. Potential importance of tissue angiotensin-converting enzyme inhibition in preventing neointima formation. Circulation 1994; 90:449-455.
10. 10 Ohishi M, Ueda M, Rakugi H, Naruko T, Kojima A, Okamura A, et al. Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans. J Hypertens 1997; 15:1295-1302.
11. 11 Ohishi M, Ueda M, Rakugi H, Okamura A, Naruko T, Becker AE, et al. Upregulation of angiotensin-converting enzyme during the healing process after injury at the site of percutaneous transluminal coronary angioplasty in humans. Circulation 1997; 96:3328-3337.
12. 12 Stary HC, Chandler AB, Dismore RE, Fuster V, Glagov S, Insull W Jr, et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 1995; 92:1355-1374.
13. 13 Fuster V. Elucidation of the role of plaque instability and rupture in acute coronary events. Am J Cardiol 1995; 76:24c-33c.
14. 14 Urata H, Strobel F, Ganten D. Widespread tissue distribution of human chymase. J Hypertens 1994; 12 (suppl 9):S17-S22.
15. 15 Liao Y, Husain A. The chymase-angiotensin system in humans: biochemistry, molecular biology and potential role in cardiovascular diseases. Can J Cardiol 1995; 11 (suppl F):13f-19f.
16. 16 Urata H, Boehm KD, Philip A, Kinoshita A, Gabrovsek J, Bumpus FM, et al. Cellular localization and regional distribution of an angiotensin II-forming chymase in the heart. J Clin Invest 1993; 91:1269-1281.
17. 17 Okunishi H, Oka Y, Shiota N, Kawamoto T, Song K, Miyazaki M. Marked species-difference in the vascular angiotensin II-forming pathways: humans versus rodents. Jpn J Pharmacol 1993; 62:207-210.
18. 18 Webb DJ, Collier JG. Vascular angiotensin conversion in humans. J Cardiovasc Pharmacol 1986; 8 (suppl 10):S40-S44.
19. 19 Balcells E, Meng QC, Hageman GR, Palmer RW, Durand JN, Dell'ltalia U. Angiotensin II formation in dog heart is mediated by different pathways in vivo and in vitro. Am J Physiol 1996; 271:H417-H421.
20. 20 Shiota N, Okunishi H, Fukamizu A, Sakonjo H, Kikumori M, Nishimura T, et al. Activation of two angiotensin-generating systems in the balloon-injured artery. FEBS Lett 1993; 323:239-242.
21. 21 Takai S, Shiota N, Kobayashi S, Matsumura E, Miyazaki M. Induction of chymase that forms angiotensin II in the monkey atherosclerotic aorta. FEBS Lett 1997; 412:86-90.
22. 22 Naruko T, Ueda M, van der Wal AC, van der Loos CM, Itoh H, Nakao K, et al. C-type natriuretic peptidc in human coronary atherosclerotic lesions. Circulation 1996; 94:3103-3108.
23. 23 Takada Y, Unno M, Hiwada K, Kokubu T. Immunological and immunofluorescent studies of human angiotensin-converting enzyme. Clin Sci 1981 ; 61 (suppl 7):253s-256s.
24. 24 Takada Y, Unno M, Hiwada K, Kokubu T. Biochemical and immunological studies of angiotensin converting enzymes from human, bovine, dog, hog, rabbit, rat and sheep kidneys. Comp Biochem Physiol [B] 1982; 73:189-194.
25. 25 van der Loos CM, Becker AE, van den Oord JJ. Practical suggestions for successful immunoenzyme double-staining experiments. Histochem J 1993; 25:1-13.
26. 26 Okunishi H, Miyazaki M, Okamura T, Toda N. Different distribution of two types of angiotensin II-generating enzymes in the aortic wall. Biochem Biophys Res Commun 1987; 149:1186-1192.
27. 27 Kaartinen M, Penttila A, Kovanen PT. Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture. Circulation 1994; 90:1669-1678.
28. 28 Kaartinen M, Penttila A, Kovanen PT. Mast cells accompany microvessels in human coronary atheromas: implications for intimai neovascularization and hemorrhage. Atherosclerosis 1996; 123:123-131.
29. 29 Lindstedt L, Lee M, Castro GR, Fruchart JC, Kovanen PT. Chymase in exocytosed rat mast cell granules effectively proteolyzes apolipoprotein Alcontaining lipoproteins, so reducing the cholesterol efflux-inducing ability of serum and aortic intimai fluid. J Clin Invest 1996; 97:2174-2182.
30. 30 Mizutani H, Schechter N, Lazarus G, Black RA, Kupper TS. Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. J Exp Med 1991 ; 174:821-825.