Isolation and identification of the major urinary metabolite of 4-(4- fluorophenoxy)benzaldehyde semicarbazone after oral dosing to rats

Pharmazie

Volumn 54, Issue 4, 1999, Pages 260-262

  Dimmock, J R ^a   Semple, H A ^a   John, S ^a   Beazely, M A ^a   Abrams, G D ^b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b College of Pharmacy and Nutrition ^*

Author keywords

[No Author keywords available]

Indexed keywords

1 [4 (4 FLUOROPHENOXY)BENZOYL]SEMICARBAZIDE; 4 (4 FLUOROPHENOXY)BENZALDEHYDE SEMICARBAZONE; DRUG METABOLITE; SEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; DISEASE SIMULATION; DOSE RESPONSE; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG METABOLISM; DRUG STRUCTURE; DRUG URINE LEVEL; MALE; MASS SPECTROMETRY; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT;

ANIMALS; ANTICONVULSANTS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; RATS; SEMICARBAZONES; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT;

EID: 0033031688     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Dimmock, J. R.; Puthucode, R. N.; Smith, J. M.; Hetherington, M.; Quail, J. M.; Pugazhenthi, U.; Lechler, T.; Stables, J. P.: J. Med. Chem. 39, 3984 (1996)
2. Low, L. K.; Castagnoli Jr., N.; in: Delgado, J. N.; Remers, W. A. (Eds.): Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry, Ninth Edition, p. 66, J. B. Lippincott Company, Philadelphia 1991
3. Kemp, D. S.; Vellaccio, F.: Organic Chemistry, pp. 799, 800, Worth Publishers, Inc., New York 1980