Characterization of ligand-induced conformational states in the β2 adrenergic receptor

Journal of Receptor and Signal Transduction Research

Volumn 19, Issue 1-4, 1999, Pages 293-300

  Kobilka, Brian ^a   Gether, Ulrik ^a   Seifert, Roland ^a   Lin, Sansan ^a   Ghanouni, Pejman ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN;

BIOASSAY; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; FLUORESCENCE SPECTROSCOPY; LIGAND BINDING; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; STOICHIOMETRY;

EID: 0033030794     PISSN: 10799893     EISSN: None     Source Type: Journal    
DOI: 10.3109/10799899909036652     Document Type: Conference Paper

References (9)

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5. Gether, U.; Lin, S.; Ghanouni, P.; Ballesteros, J.A.; Weinstein, H.; and Kobilka, B.K. Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor. EMBO J. 16, 6737-6747, 1997.
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7. Gether, U.; Lin, S.; and Kobilka, B.K. Fluorescent labeling of purified beta 2 adrenergic receptor. Evidence for ligand-specific conformational changes. J. Biol. Chem. 270, 28268-28275, 1995.
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9. sα has properties of a consititutively active receptor. J. Biol. Chem 273, 5109-5116, 1998.