Distribution of TNF-α, TNF-R55 and TNF-R75 in the rheumatoid synovial mernbrane: TNF receptors are localized preferentially in the lining layer; TNF-α is distributed mainly in the vicinity of TNF receptors in the deeper layers

Scandinavian Journal of Immunology

Volumn 49, Issue 3, 1999, Pages 278-285

  Alsalameh, S ^a   Winter, K ^a   Al Ward, R ^a   Wendler, J ^a   Kalden, J R ^a   Kinne, Raimund W ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ADULT; AGED; ARTICLE; CELL ISOLATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCHEMISTRY; IMMUNOFLUORESCENCE; MALE; PATHOGENESIS; PATIENT SELECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR BINDING; RHEUMATOID ARTHRITIS; SYNOVIUM;

ADULT; AGED; ANTIGENS, CD; ARTHRITIS, RHEUMATOID; CELL SEPARATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; SOLUBILITY; SYNOVIAL MEMBRANE; TISSUE DISTRIBUTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033030206     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1999.00458.x     Document Type: Article

References (49)

1. 1 Vassalli P. The pathophysiology of tumor necrosis factors. Annu Rev Immunol 1992;10:411-52.
2. 2 Gearing AJH, Beckett P, Christodoulon M et al. Processing of tumor necrosis factor-α precursor by metalloproteinases. Nature 1994;370:555-7.
3. 3 Perez C, Albert I, DeFay K, Zacharias N, Gooding L, Kriegler M. A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact. Cell 1990;63:251-8.
4. + T cell clones provides a costimulatory signal for human B cell activation. J Exp Med 1993;177:1575-85.
5. 5 Schall TJ, Lewis M, Koller KJ et al. Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 1990;61:361-70.
6. 6 Gray PW, Barrett K, Chantry D, Turner M, Feldmann M. Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein. Proc Natl Acad Sci USA 1990;87:7380-4.
7. 7 Brockhaus M, Schoenfeld H-J, Schlaeger E-J, Hunziker W, Lesslauer W, Loetscher H. Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies. Proc Natl Acad Sci USA 1990;87:3127-31.
8. 8 Lewis M, Tartaglia LA, Lee A et al. Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc Natl Acad Sci USA 1991;88:2830-4.
9. 9 Thoma B, Grell M, Pfizenmaier K, Scheurich P. Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses. J Exp Med 1990;172:1019-23.
10. 10 Dembic Z, Loetscher H, Gubler U et al. Two human TNF receptors have similar extracellular, but distinct intracellular domain sequences. Cytokine 1990;2:231-7.
11. 11 Grell M, Zimmermann G, Hülser D, Pfizenmaier K, Scheurich P. TNF receptors TR60 and TR80 can mediate apoptosis via induction of distinct signal pathways. J Immunol 1994;153:1963-72.
12. 12 Mackay F, Loetscher H, Stueber D, Gehr G, Lesslauer W. Tumor necrosis factor α (TNF-α)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55. J Exp Med 1993;177:1277-86.
13. 13 Brakebusch C, Nophar Y, Kemper O, Engelmann H, Wallach D. Cytoplasmic truncation of the p55 tumor necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor. EMBO J 1992;11:943-50.
14. 14 Tartaglia LA, Weber RF, Figari IS, Reynolds C, Palladino MA, Goeddel DV. The two different receptors for tumor necrosis factor mediate distinct cellular responses. Proc Natl Acad Sci USA 1991;88:9292-6.
15. 15 Vandenabeele P, Declercq W, Vercammen D et al. Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma. J Exp Med 1992;176:1015-24.
16. 16 Tartaglia LA, Goeddel DV, Reynolds C et al. Stimulation of human T-cell proliferation by specific activation of the 75-kD tumor necrosis factor receptor. J Immunol 1993;151:4637-41.
17. 17 Tartaglia LA, Pennica D, Goeddel DV. Ligand passing: the 75-kD tumor necrosis factor (TNF) receptor recruits TNF for signalling by the 55-kD TNF receptor. J Biol Chem 1993;268:18542-8.
18. 18 Grell M, Scheurich P, Meager A, Pfizenmaier K. TR60 and TR80 tumor necrosis factor (TNF)-receptors can independently mediate cytolysis. Lymphokine Cytokine Res 1993;12:143-8.
19. 19 Grell M, Douni E, Wajant H et al. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80-kD tumor necrosis factor receptor. Cell 1995;83:793-802.
20. 20 Weiss T, Grell M, Hessabi B et al. Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site. J Immunol 1997;158:2398-404.
21. 21 Maini RN, Brennan FM, Williams R et al. TNF-α in rheumatoid arthritis and prospects of anti-TNF therapy. Clin Exp Rheumatol 1993;8:173-5.
22. 22 Cooper WO, Fava RA, Gates CA, Cremer MA, Townes AS. Acceleration of onset of collagen-induced arthritis by intra-articular injection of tumor necrosis factor or transforming growth factor-beta. Clin Exp Immunol 1992;89:244-50.
23. 23 Keffer J, Probert L, Cazlaris H et al. Transgenic mice expressing human tumor necrosis factor: a predictive genetic model of arthritis. EMBO J 1991;10:4025-31.
24. 24 Elliott MJ, Maini RN, Feldmann M et al. Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α. Arthritis Rheum 1993;36:1681-90.
25. 25 Williams RO, Feldmann M, Maini RN. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci USA 1992;89:9784-8.
26. 26 Wooley PH, Dutcher J, Widmer MB, Gillis S. Influence of a recombinant human soluble tumor necrosis factor receptor Fc fusion protein on type II collagen-induced arthritis in mice. J Immunol 1993;51:6602-7.
27. 27 Elliott MJ, Maini RN, Feldmann M et al. Randomized double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-27.
28. 28 Moreland LW, Baumgartner SW, Schiff MH et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 1997;337:141-7.
29. 29 Mussener A, Klareskog L, Lorentzen JC, Kleinau S. TNF-alpha dominates cytokine mRNA expression in lymphoid tissues of rats developing collagen-and oil-induced arthritis. Scand J Immunol 1995;42:128-34.
30. 30 Neidel J, Schulze M, Lindschau J. Association between degree of bone-erosion and synovial fluid-levels of tumor necrosis factor alpha in the knee joints of patients with rheumatoid arthritis. Inflamm Res 1995;44:217-21.
31. 31 Arnett FC, Edworthy SM, Block DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
32. 32 Emmrich F, Gebauer F, Weseloh G, Kinne R. Phenotype analysis of 'inflammatory' macrophages in rheumatoid arthritis by two-colour cytofluorometry and immunohistology. Agents Actions 1990;29:95-7.
33. 33 Alsalameh S, Mollenhauer J, Hain N, Stock K-P, Kalden JR, Burmester GR. Cellular immune response toward human articular chondrocytes. T cell reactivity against chondrocyte and fibroblast membranes in destructive joint diseases. Arthritis Rheum 1990;33:1477-86.
34. 34 Eissner G, Kohlhuber F, Grell M et al. Critical involvement of transmembrane tumor necrosis factor-alpha in endothelial programmed cell death mediated by ionizing radiation and bacterial endotoxin. Blood 1995;86:4184-93.
35. 35 Mulherin D, Fitzgerald O, Bresnihan B. Synovial tissue macrophage populations and articular damage in rheumatoid arthritis. Arthritis Rheum 1996;39:115-24.
36. 36 Arend WP, Dayer J-M. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis (review). Arthritis Rheum 1995;38:151-9.
37. 37 Chu CQ, Field M, Feldmann M, Maini RN. Localization of tumor necrosis factor α in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 1991;34:1125-32.
38. 38 Tetta C, Camussi G, Modena V, Di Vittorio C, Baglioni C. Tumour recrosis factor in serum and synovial fluid of patients with active and severe rheumatoid arthritis. Ann Rheum Dis 1990;49:665-7.
39. 39 Klimiuk PA, Goronzy JJ, Björnsson J, Beckenbaugh RD, Weyand CM. Tissue cytokine patterns distinguish variants of rheumatoid synovitis. Am J Pathol 1997;151:1311-19.
40. 40 Youssef PP, Kraan M, Breedveld F et al. Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples obtained blindly by needle biopsy. Arthritis Rheum 1998;41:663-9.
41. 41 Parry SL, Sebbag M, Feldmann M, Brennan FM. Contact with T cells modulates monocyte IL-10 production: role of T cell membrane TNF-alpha. J Immunol 1997;158:3673-81.
42. 42 Georgopoulos S, Plows D, Kollias G. Transmembrane TNF is sufficient to induce localized tissue toxicity and chronic inflammatory arthritis in transgenic mice. J Inflamm 1996;46: 86-9.
43. 43 Alexopoulou L, Pasparakis M, Kollias G. A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling. Eur J Immunol 1997;27:2588-95.
44. 44 Scallon BJ, Moore MA, Trink H, Knight DM, Ghrayeb J. Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions. Cytokine 1995;7:251-9.
45. 45 Deleuran BW, Chu CQ, Field M et al. Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junctions in patients with rheumatoid arthritis. Arthritis Rheum 1992;35:1170-8.
46. 46 Kalthoff H, Roeder C, Brockhaus M, Thiele HG, Schmiegel W. Tumor necrosis factor (TNF) up-regulates the expression of p75 but not p55 receptors, and both receptors mediate, independently of each other, up-regulation of transforming growth factor α and epidermal growth factor recptor mRNA. J Biol Chem 1993;268:2762-6.
47. 47 Winzen R, Wallach D, Kemper O, Resch K, Holtmann H. Selective up-regulation of the 75-kDa tumor necrosis factor (TNF) receptor and its mRNA by TNF and IL-1. J Immunol 1993;150:4346-53.
48. 48 Heilig B, Mapara M, Brockhaus M, Krauth K, Dörken B. Two types of TNF receptors are expressed on human normal and malignant B lymphocytes. Clin Immunol Immunopath 1991;61:260-7.
49. 49 Alsalameh S, Mattka B, Al-Ward R et al. Preferential expression of TNF-R55 on human articular chondrocytes. IL-1β, TNF-alpha and basic FGF selectively modulate the mRNA expression of TNF-R75. J Rheumatol 1999;in press.