Delayed graft function: Risk factors and the relative effects of early function and acute rejection on long-term survival in cadaveric renal transplantation

Clinical Transplantation

Volumn 13, Issue 3, 1999, Pages 266-272

  McLaren, Andrew J ^a   Jassem, W ^a   Gray, D W R ^a   Fuggle, S V ^a   Welsh, K I ^b   Morris, P J ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

Acute rejection; DGF; Renal transplant

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; METHYLPREDNISOLONE;

ADULT; ARTICLE; CADAVER KIDNEY; DATA BASE; FEMALE; GRAFT SURVIVAL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY FUNCTION; KIDNEY GRAFT REJECTION; KIDNEY ISCHEMIA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REGRESSION ANALYSIS; RISK FACTOR; SURVIVAL TIME;

ADULT; CADAVER; CHI-SQUARE DISTRIBUTION; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; INCIDENCE; ISCHEMIA; KIDNEY TRANSPLANTATION; MIDDLE AGED; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 0033025942     PISSN: 09020063     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0012.1999.130308.x     Document Type: Article

References (33)

1. TROPPMANN C, GILLINGHAM K, BENEDETTI E, ALMOND P, GRUESSNER R, NAJARIAN J, MATAS A. Delayed graft function, acute rejection, and outcome after cadaver renal transplantation. Transplantation 1995: 59: 962.
2. NICHOLSON M, WHEATLEY T, HORSBURGH T, EDWARDS C, VEITCH P, BELL P. The relative influence of delayed graft function and acute rejection on renal transplant survival. Transpl Int 1996: 9: 415.
3. LEHTONEN S, ISONIEMI H, SALMELA K, TASKINEN E, WILLEBRAND E, AHONEN J. Long-term graft outcome is not necessarily affected by delayed onset of graft function and early acute rejection. Transplantation 1997: 64 (1): 103.
4. OJO A, WOLFE R, HELD P, PORT F, SCHMOUDER R. Delayed graft function: risk factors and implications for renal allograft survival. Transplantation 1997: 63 (7): 968.
5. PFAFF W, HOWARD R, PATTON P, ADAMS V, ROSEN C. REED A. Delayed graft function after renal transplantation. Transplantation 1998: 65 (2): 219.
6. HALLORAN P, APRILE M, FAREWELL V, LUDWIN D. SMITH E, TSAI S, BEAR R, COLE E, FENTON S, CATTRAN DC. Early function as the principal correlate of graft survival. Transplantation 1988: 46: 223.
7. PIRSCH J, PLOEG R, GANGE S, D'ALESSANDRO A, KNECHTLE S, SOELINGER H, KALAYOGLU M, BELZER F. Determinants of graft survival after renal transplantation. Transplantation 1996: 61 (11): 1581.
8. HUMAR A, JOHNSON E, PAYNE W, WRENSHALL L, SUTHERLAND D, NAJARIAN J, GILLINGHAM K, MATAS A. Effect of initial slow graft function on renal allograft rejection and survival. Clin Transplant 1997: 11: 623.
9. TROPPMANN C, GILLINGHAM K, BENEDETTI E, ALMOND P, GRUESSNER R, NAJARIAN J, MATAS A. Delayed graft function, acute rejection, and outcome after cadaver renal transplantation. Transplantation 1995: 59: 962.
10. ICHIKAWA Y, HASHIMOTO M, HANAFUSA T, KYO M, FUJIMOTO N, MATSUURA O, TAKAHARA S, HAYASHI R, IHARA H, ONO Y, SUZUKI S, FUKUNISHI T, OHSHIMA S, NAGANO S. Delayed graft function does not influence long-term outcome on cadaver kidney transplants without mismatch for HLA-DRB1. Transpl Int 1995: 8: 421.
11. MASSY Z, GUIJARRO C, WIEDERKEHR M. MA J, KASISKE B. Chronic renal allograft rejection: immunologic and non-immunologic risk factors. Kidney Int 1996: 49: 518.
12. MCLAREN A. FUGGLE S, GRAY D, WELSH K, MORRIS P. Chronic allograft failure in human renal transplantation a multivariate risk factor analysis. 1998 (in preparation).
13. TROPPMANN C, GILLINGHAM K, BENEDETTI E, ALMOND P, GRUESSNER R, NAJARIAN J, MATAS A. Delayed graft function in the absence of acute rejection has no longterm impact. Transplantation 1996: 61: 1331.
14. HOWARD R, PFAFF E W, BRUNSON M. SCORNIK J, RAMOS E, PETERSON J, FENNELL R, CROKER B. Increased incidence of rejection in patients with delayed graft function. Clin Transpl 1994: 6: 527.
15. SHOSKES D, HALLORAN P. Ischaemic injury induces altered MHC expression in kidney, by an interferon-gamma dependent pathway. Transpl Proc 1991: 23: 599.
16. TAKADA M, NADEAU K, SHAW G, TILNEY N. Prevention of late renal changes after initial ischaemia/reperfusion injury by blocking early selectin binding. Transplantation 1997: 64 (11): 1520.
17. JONES R, MURIE J, ALLEN R, TING A, MORRIS P. Triple therapy in cadaver renal transplantation. Br J Surg 1988: 75: 4.
18. BAUMA W, TANG I, MADDUX M, VEREMIS S, POLLACK R, MOZES M. Delayed graft function following cadaver renal transplantation in the cyclosporine era: analysis of acute rejection and graft survival. Transpl Proc 1989: 21: 1276.
19. HOWARD R, PLAFF W, BRUNSON M, RAMOS E, PETERSON J, CROKER B, SCORNIK J, PARRIS C, FENNELL R. Delayed graft function is associated with an increased incidence of occult rejection and results in poorer graft survival. Transpl Proc 1993: 25 (1): 884.
20. NAJARIAN J, GILLINGHAM K, SUTHERLAND D, REINSMOEN N, PAYNE W, MATAS A. The impact of the quality of initial graft function on cadaver kidney transplants. Transplantation 1994: 57: 812.
21. D'ALLESANDRO A, SOLLINGER H, KNECHTLE S, KALAYOGLU M, KISKEN W, UEHLING D, MOON T, MESSING E, BRUSKEWITZ R, PIRSCH J. Living related and unrelated donors for kidney transplantation. A 28-year experience. Ann Surg 1995: 222 (3): 353.
22. TERASAKI P, CECKA J, GJERTSON D, TAKEMOTO S. High survival rates of kidney transplants from spousal and living unrelated donors. New Engl J Med 1995: 333: 333.
23. JASSEM W, ROAKE J. The molecular and cellular basis of reperfusion injury following organ transplantation. Transpl Rev 1998: 12 (1): 14.
24. MCCORD J. Oxygen-derived free radicals in post-ischaemic tissue injury. New Engl J Med 1985: 312 (3): 159.
25. CHULUYAN H, SCHALL T, YOSHIMURA T, ISSEKUTZ A. IL-1 activation of endothelium supports VLA-4 (CD49d CD29)-mediated monocyte transendothelial migration to C5a, MIP-1α, RANTES and PAF but inhibits migration to MCP-1: a regulatory role for endothelium derived MCP-1. J Leucoc Biol 1995: 58 (1): 71.
26. LEHR H, GUHLMANN A, NOLTE D, KEPPLER D, MESSMER K. Leukotrienes as mediators in ischaemia-reperfusion injury in a micro-circulation model in the hamster. J Clin Invest 1991: 87 (6): 2036.
27. FUGGLE S, SANDERSON J, GRAY D, RICHARDSON A, MORRIS P. Variation in expression of endothelial adhesion molecules in pretransplant and transplanted kidneys correlation with intragraft events. Transplantation 1993: 55 (1): 117.
28. HAYRY P. Pathophysiology of chronic rejection. Transpl Proc 1996: 28(6) suppl 1: 7.
29. AZUMA H, NADEAU K, MACKENZIE H, BRENNER B, TILNEY N. Nephron mass modulates the haemodynamic. cellular and molecular response of the rat renal allograft. Transplantation 1997: 63 (4): 519.
30. KONING O, PLOEG R, VAN BOCKEL J, GROENEWEGEN M, WOUDE F, PERSIJN G, HERMANS J. Risk factors for delayed graft function in cadaveric renal transplantation. Transplantation 1997: 63: 1620.
31. FEUCHT H, SCHNEEBERGER H, HILLEBRAND G, BURKHARDT K, WEISS M, RIETHMULLER, G, LAND W, ALBERT E. et al. Capillary deposition of C4d complement fragment and early graft loss. Kidney Int 1993: 43: 1333.
32. SCHNEEBERGER H, SCHLEIBNER S, ILLNER W, MEEMER K, LAND W. The impact of free radical-mediated reperfusion injury on acute and chronic rejection events following cadaveric renal transplantation. Clin Transpl 1993: 7: 219.
33. HOURMANT M, BEDROSSIAN J, DURAND D, LEBRANCHU Y, RENOULT E, CAUDRELIER P, BUFFETT R, SOULILLOU J-P. A randomised multicenter trial comparing leukocyte function-associated antigen-1 monoclonal antibody with rabbit antithymocyte globulin as induction treatment in first kidney transplants. Transplantation 1996: 62 (11): 1565.