Differential responsiveness to autocrine and exogenous transforming growth factor (TGF) β1 in cells with nonfunctional TGF-β receptor type III

Cell Growth and Differentiation

Volumn 10, Issue 1, 1999, Pages 11-18

  Deng, Xiaobing ^a   Bellis, Susan ^a   Yan, Zhongfa ^a   Friedman, Eileen ^a  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; MESSENGER RNA; MUCIN; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CELL MATURATION; COLUMNAR EPITHELIUM; CONTROLLED STUDY; GENE EXPRESSION; GOBLET CELL; INTESTINE CRYPT; INTESTINE EPITHELIUM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; ANTIGENS, CD29; CELL DIFFERENTIATION; CELL LINE; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; GOBLET CELLS; HUMANS; INTESTINES; MICE; PROTEIN-SERINE-THREONINE KINASES; PROTEOGLYCANS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 0033024663     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Cui, W., and Akhurst, R. TGFβ: biochemistry and biology in vitro and in vivo. In: C. Bondy and D. LeRoith (eds. ), Growth Factors and Cytokines in Health and Disease, pp. 531-542. Greenwich, CT: JAI Press, 1996.
2. Lin, H., Wang, X-F., Ng-Eaton, E., Weinberg, R., and Lodish, H. Expression cloning of the TGFβ type II receptor, a functional transmembrane serine/threonine kinase, Cell, 68: 775-785, 1992.
3. Franzen, P., ten Dijke, P., Ichijo, H., Yamashita, H., Schultz, P., Heldin, D., and Miyazono, K. Cloning of a TGFβ type I receptor that forms a heterodimeric complex with the TGFβ type II receptor. Cell, 75: 681-692, 1993.
4. Wrana, J., Attisano, L., Wieser, R., Ventura, F., and Massague, J. Mechanism of activation of the TGFβ receptor. Nature (Lond.), 370: 341-347, 1994.
5. Lopez-Casillas, F., Cheifetz, S., Doody, J., Andres, J., Lane, W., and Massague, J. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGFβ receptor system. Cell, 67: 785-795, 1991.
6. Lastres, P., Letamendia, A., Zhang, H., Rius, C., Almendro, N., Raab, U., Lopez, L., Langa, C., Fabra, A., Letarte, M., and Bernabeu, C. Endoglin modulates cellular responses to TGFβ1. J. Cell Biol., 133: 1109-1121, 1996.
7. Wang, X.-F., Lin, H., Ng-Eaton, E., Downward, J., and Lodish, H. Expression cloning and characterization of the TGFβ type III receptor. Cell, 67: 797-805, 1991.
8. Ewton, D., Spizz, G., Olson, E., and Florini, J. Decrease in TGFβ binding and action during differentiation in muscle cells. J. Biol. Chem., 263: 4029-4032, 1988.
9. Pelton, R., Saxena, B., Jones, M., Moses, H., and Gold, L. Immunohistochemical localization of TGFβ1, TGFβ2 and TGFβ3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J. Cell Biol., 115: 1091-1105, 1991.
10. Thomas, D., Nasim, M., Gullick, W., and Alison, M. Immunoreactivity of transforming growth factor α in the normal adult gastrointestinal tract. Gut, 33: 628-631, 1992.
11. Hafez, M., Infante, D., Winawer, S., Friedman, E., Yan, Z., Hsu, S., Winawer, S., and Friedman, E. Transforming growth factor β1 acts as an autocrine negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation. Cell Growth Differ., 1: 617-626, 1990.
12. Hafez, M., Hsu, S., Yan, Z., Winawer, S., and Friedman, E. Two roles for transforming growth factor β1 in colon enterocytic differentiation. Cell Growth Differ., 3: 753-762, 1992.
13. Barnard, J. A., Beauchamp, R. D., Coffey, R. J., and Moses, H. L. Regulation of intestinal epithelial cell growth by TGFβ. Proc. Natl. Acad. Sci. USA, 86: 1578-1582, 1989.
14. Migdalska, A., Molineux, G., Demuynck, H., Evans, G., Ruscetti, F., and Dexter, T. Growth inhibitory effects of TGFβ1 in vivo. Growth Factors, 4: 239-245, 1991.
15. Yan, Z., Hsu, S., Winawer, S., and Friedman, E. TGFβ inhibits retinoblastoma gene expression but not pRB phosphorylation in TGFβ1-growth-stimulated colon carcinoma cells. Oncogene, 7: 801-805, 1992.
16. Markowitz, S., Wang, J., Myeroff, L., Parsons, R., Sun, L., Lutterbaugh, J., Fan, R., Zborowska, E., Kinzler, K., Vogelstein, B., Brattain, M., and Willson, J. Inactivation of the type II TGFβ receptor in colon cancer cells with microsatellite instability. Science (Washington DC), 268: 1336-1338, 1995.
17. Knaus, P., Lindemann, D., Decoteau, J., Perlman, R., Yankelev, H., Hille, M., Kadin, M., and Lodish, H. A dominant inhibitory mutant of the type II TGFβ receptor in the malignant progression of a cutaneous T-cell lymphoma. Mol. Cell. Biol., 16: 3480-3489, 1996.
18. Lopez-Casillas, F., Wrana, J., and Massague, J. Betaglycan presents ligand to the TGFβ signaling receptor. Cell, 73: 1435-1444, 1993.
19. Datto, M., Li, Y., Panus, J., Howe, D., Xiong, Y., and Wang, X. TGFβ induces the cdk inhibitor p21 through a p53-independent mechanism. Proc. Natl. Acad. Sci. USA, 92: 5545-5549, 1995.
20. Hsu, S., Huang, F., Hafez, M., Winawer, S., and Friedman, E. Colon carcinoma cells switch their response to transforming growth factor β1 with tumor progression. Cell Growth Differ., 5: 267-275, 1994.
21. Heino, J., Ignotz, R., Hemler, M., Crouse, C., and Massague, J. Regulation of cell adhesion receptors by TGFβ. J. Biol. Chem., 264: 380-388, 1989.
22. 1 integrin maturation in colon epithelial cells. J. Biol. Chem., 272: 30928-30937, 1997.
23. Chen, C., Wang, X-F., and Sun, L. Expression of the TGFβ type III receptor restores autocrine TGFβ1 activity in human breast cancer MCF-7 cells. J. Biol. Chem., 272: 12862-12867, 1997.
24. Amoroso, S., Huang, N., Roberts, A., Potter, M., and Letterio, J. Consistent loss of functional TGFβ receptor expression in murine plasmacytomas. Proc. Natl. Acad. Sci. USA, 95: 189-194, 1998.
25. Fynan, T., and Reiss, M. Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis. Crit. Rev. Oncog., 4: 493-540, 1993.
26. Riggins, G., Kinzler, K., Vogelstein, B., and Thagalingam, S. Frequency of Smad gene mutations in human cancers. Cancer Res., 57: 2578-2580, 1997.
27. Zhu, Y., Richardson, J., Parada, L., and Graff, J. Smad3 mutant mice develop metastatic colorectal cancer. Cell, 94: 703-714, 1998.
28. Keely, P., Parise, L., and Juliano, R. Integrins and GTPases in tumour cell growth, motility and invasion. Trends Cell Biol., 8: 101-106, 1998.
29. Truong, L., Kadmon, D., McCune, B., Flanders, K., Scardino, P., and Thompson, T. Association of TGFβ1 with prostate cancer. Hum. Pathol., 24: 4-9, 1993.
30. Friedman, E., Gold, L., Klimstra, D., Zeng, Z., Winawer, S., and Cohen, A. High levels of transforming growth factor β1 correlate with disease progression in human colon cancer. Cancer Epidemiol. Biomark. Prev., 4: 549-554, 1995.
31. Sehgal, I., Baley, P., and Thompson, T. Transforming growth factor β1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro. Cancer Res., 56: 3359-3365, 1996.