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Volumn 5, Issue 6, 1999, Pages 1509-1516

Phenylbutyrate induces cell differentiation and modulates Epstein-Barr virus gene expression in Burkitt's lymphoma cells

Author keywords

[No Author keywords available]

Indexed keywords

ARYLBUTYRIC ACID DERIVATIVE; DIFFERENTIATION INDUCING FACTOR; PHENYLACETIC ACID; PHENYLBUTYRIC ACID; UNCLASSIFIED DRUG;

EID: 0033024624     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (19)

References (52)
  • 1
    • 0025819140 scopus 로고
    • African Burkitt's lymphoma. History, biology, clinical features, and treatment
    • Magrath, I. T. African Burkitt's lymphoma. History, biology, clinical features, and treatment. Am. J. Pediatr. Hematol. Oncol., 13: 222-226, 1991.
    • (1991) Am. J. Pediatr. Hematol. Oncol. , vol.13 , pp. 222-226
    • Magrath, I.T.1
  • 2
    • 0029832362 scopus 로고    scopus 로고
    • The association of the Epstein-Barr virus with malignant lymphorna
    • Chang, K. L., and Weiss, L. M. The association of the Epstein-Barr virus with malignant lymphorna. Biomed. Pharmacother., 50: 459-467, 1996.
    • (1996) Biomed. Pharmacother. , vol.50 , pp. 459-467
    • Chang, K.L.1    Weiss, L.M.2
  • 3
    • 0029843330 scopus 로고    scopus 로고
    • Treatment of Burkitt's lymphoma in HIV-positive patients
    • Straus, D. J. Treatment of Burkitt's lymphoma in HIV-positive patients. Biomed. Pharmacother., 50: 447-450, 1996.
    • (1996) Biomed. Pharmacother. , vol.50 , pp. 447-450
    • Straus, D.J.1
  • 4
    • 0027275755 scopus 로고
    • Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas
    • Bhatia, K., Huppi, K., Spangler, G., Siwarski, D., Iyer, R., and Magrath, I. Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas. Nat. Genet., 5: 56-61, 1993.
    • (1993) Nat. Genet. , vol.5 , pp. 56-61
    • Bhatia, K.1    Huppi, K.2    Spangler, G.3    Siwarski, D.4    Iyer, R.5    Magrath, I.6
  • 5
    • 0025248108 scopus 로고
    • Deregulated c-myc expression in Epstein-Barr virus-immortalized B-cells induces altered growth properties and surface phenotype but not tumorigencity
    • Hotchin, N. A., Allday, M. J., and Crawford D. H. Deregulated c-myc expression in Epstein-Barr virus-immortalized B-cells induces altered growth properties and surface phenotype but not tumorigencity. Int. J. Cancer, 45: 566-571, 1990.
    • (1990) Int. J. Cancer , vol.45 , pp. 566-571
    • Hotchin, N.A.1    Allday, M.J.2    Crawford, D.H.3
  • 6
    • 0025224909 scopus 로고
    • Epstein-Barr virus latency and activation in vivo
    • Ernberg, I. Epstein-Barr virus latency and activation in vivo. Curr. Top. Microbiol., 166: 337-346, 1990.
    • (1990) Curr. Top. Microbiol. , vol.166 , pp. 337-346
    • Ernberg, I.1
  • 7
    • 0023409797 scopus 로고
    • Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells
    • Rowe, M., Rowe, D. T., Gregory, C. D., Young, L. S., Farrell, P. J., Rupani, H., and Rickinson, A. B. Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells. EMBO J., 6: 2743-2751, 1987.
    • (1987) EMBO J. , vol.6 , pp. 2743-2751
    • Rowe, M.1    Rowe, D.T.2    Gregory, C.D.3    Young, L.S.4    Farrell, P.J.5    Rupani, H.6    Rickinson, A.B.7
  • 8
    • 0027466809 scopus 로고
    • Antigen processing and presentation by EBV-carrying cell lines: Cell-phenotype dependence and influence of the EBV-encoded LMP1
    • de Campos-Lima, P. O., Torsteinsdottir, S., Cuomo, L., Klein, G., Sulitzeanu, D., and Masucci, M. G. Antigen processing and presentation by EBV-carrying cell lines: cell-phenotype dependence and influence of the EBV-encoded LMP1. Int. J. Cancer, 53: 856-862, 1993.
    • (1993) Int. J. Cancer , vol.53 , pp. 856-862
    • De Campos-Lima, P.O.1    Torsteinsdottir, S.2    Cuomo, L.3    Klein, G.4    Sulitzeanu, D.5    Masucci, M.G.6
  • 9
    • 0026673101 scopus 로고
    • Cytotoxic T lymphocytes show HLA-C-restricted recognition of EBV-bearing cells and allorecognition of HLA class I molecules presenting self-peptides
    • Schendel, D. J., Reinhardt, C., Nelson, P. J., Maget, B., Pullen, L., Bornkamm, G. W., and Steinle, A. Cytotoxic T lymphocytes show HLA-C-restricted recognition of EBV-bearing cells and allorecognition of HLA class I molecules presenting self-peptides. J. Immunol., 149: 2406-2414, 1992.
    • (1992) J. Immunol. , vol.149 , pp. 2406-2414
    • Schendel, D.J.1    Reinhardt, C.2    Nelson, P.J.3    Maget, B.4    Pullen, L.5    Bornkamm, G.W.6    Steinle, A.7
  • 10
    • 0023195028 scopus 로고
    • Down-regulation of class I HLA antigens and of the Epstein-Barr virus-encoded latent membrane protein in Burkitt's lymphoma lines
    • Masucci, M. G., Torsteindottir, S., Colombani, J., Brautbar, C., Klein, E., and Klein, G. Down-regulation of class I HLA antigens and of the Epstein-Barr virus-encoded latent membrane protein in Burkitt's lymphoma lines. Proc. Natl. Acad. Sci., 84: 4567-4571, 1987.
    • (1987) Proc. Natl. Acad. Sci. , vol.84 , pp. 4567-4571
    • Masucci, M.G.1    Torsteindottir, S.2    Colombani, J.3    Brautbar, C.4    Klein, E.5    Klein, G.6
  • 12
    • 0021280711 scopus 로고
    • Effects of n-butyrate and phorbol ester (TPA) on induction of Epstein-Barr virus antigens and cell differentiation
    • Anisimova, E., Prachova Roubal, J., and Vonka, V. Effects of n-butyrate and phorbol ester (TPA) on induction of Epstein-Barr virus antigens and cell differentiation. Arch. Virol., 84: 223-237, 1984.
    • (1984) Arch. Virol. , vol.84 , pp. 223-237
    • Anisimova, E.1    Prachova Roubal, J.2    Vonka, V.3
  • 13
    • 0023423241 scopus 로고
    • Truncation does not abrogate transcriptional down-regulation of the c-myc gene by sodium butyrate in Burkitt's lymphorna cells
    • Polack, A., Eick, D., Koch, E., and Bornkamm, G. W. Truncation does not abrogate transcriptional down-regulation of the c-myc gene by sodium butyrate in Burkitt's lymphorna cells. EMBO J., 6: 2959-2964, 1987.
    • (1987) EMBO J. , vol.6 , pp. 2959-2964
    • Polack, A.1    Eick, D.2    Koch, E.3    Bornkamm, G.W.4
  • 14
    • 0018384722 scopus 로고
    • Induction of the epstein-barr virus (EBV) cycle in latently infected cells by n-butyrate
    • Luka, J., Kallin, B., and Klein, G. Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-butyrate. Virology, 94: 228-231, 1979.
    • (1979) Virology , vol.94 , pp. 228-231
    • Luka, J.1    Kallin, B.2    Klein, G.3
  • 15
    • 0019176585 scopus 로고
    • Effect of n-butyrate on cellular and viral DNA synthesis in cells latently infected with Epstein-Barr virus
    • Saemundsen, A. K., Kallin, B., and Klein, G. Effect of n-butyrate on cellular and viral DNA synthesis in cells latently infected with Epstein-Barr virus. Virology, 107: 557-561, 1980.
    • (1980) Virology , vol.107 , pp. 557-561
    • Saemundsen, A.K.1    Kallin, B.2    Klein, G.3
  • 16
    • 0025076854 scopus 로고
    • Up-regulation of the Epstein-Barr virus (EBV)-encoded membrane protein LMP in the Burkitt's lymphoma line Daudi after exposure to n-butyrate and after EBV superinfection
    • Contreras-Salazar, B., Ehlin-Henriksson, B., Klein, G., and Masucci, M. G. Up-regulation of the Epstein-Barr virus (EBV)-encoded membrane protein LMP in the Burkitt's lymphoma line Daudi after exposure to n-butyrate and after EBV superinfection. J. Virol., 64: 5441-5447, 1990.
    • (1990) J. Virol. , vol.64 , pp. 5441-5447
    • Contreras-Salazar, B.1    Ehlin-Henriksson, B.2    Klein, G.3    Masucci, M.G.4
  • 17
    • 0026636474 scopus 로고
    • Phenylacetate. A novel nontoxic inducer of tumor cell differentiation
    • Samid, D., Shack, S., and Sherrnan, L. T. Phenylacetate. A novel nontoxic inducer of tumor cell differentiation. Cancer Res., 52: 1988-1992, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 1988-1992
    • Samid, D.1    Shack, S.2    Sherrnan, L.T.3
  • 18
    • 0028130435 scopus 로고
    • Differentiation of cultured human melanoma cells induced by the aromatic fatty acids phenylacetate and phenylbutyrate
    • Liu, L., Shack, S., Stetler-Stevenson, W. G., Hudgins, W. R., and Samid D. Differentiation of cultured human melanoma cells induced by the aromatic fatty acids phenylacetate and phenylbutyrate. J. Invest. Dermatol., 103: 335-340, 1994.
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 335-340
    • Liu, L.1    Shack, S.2    Stetler-Stevenson, W.G.3    Hudgins, W.R.4    Samid, D.5
  • 20
    • 0004143398 scopus 로고    scopus 로고
    • A phase I study of the differentiating agent phenylbutyrate in patients with cancer
    • Thibault, A., Figg, W. D., and Samid, D. A phase I study of the differentiating agent phenylbutyrate in patients with cancer. Proc. Am. Soc. Clin. Oncol., 15: 484-491, 1996.
    • (1996) Proc. Am. Soc. Clin. Oncol. , vol.15 , pp. 484-491
    • Thibault, A.1    Figg, W.D.2    Samid, D.3
  • 21
    • 0026730287 scopus 로고
    • Induction of erythroid differentiation and fetal hemoglobin production human leukemic cells treated with phenylacetate
    • Samid, D., Yeh, A., and Prasanna, P. Induction of erythroid differentiation and fetal hemoglobin production human leukemic cells treated with phenylacetate. Blood, 80: 1576-1581, 1992.
    • (1992) Blood , vol.80 , pp. 1576-1581
    • Samid, D.1    Yeh, A.2    Prasanna, P.3
  • 22
    • 0030861882 scopus 로고    scopus 로고
    • Impact of the putative differentiating agents sodium phenylbutyrate and sodium phenylacetate on proliferation, differentiation, and apoptosis of primary neoplastic myeloid cells
    • Gore, S. D., Samid, D., and Weng, L-J. Impact of the putative differentiating agents sodium phenylbutyrate and sodium phenylacetate on proliferation, differentiation, and apoptosis of primary neoplastic myeloid cells Clin. Cancer Res., 3: 1755-1762, 1997.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 1755-1762
    • Gore, S.D.1    Samid, D.2    Weng, L.-J.3
  • 23
    • 0028210550 scopus 로고
    • Selective activity of phenylacetate against malignant gliomas: Resemblance to fetal brain damage in phenylketonuria
    • Samid, D., Ram, Z., Hudgins, W. R., Shack, S., Liu, L., Walbridge, S., Oldfield, E. H., and Myers, C. E. Selective activity of phenylacetate against malignant gliomas: resemblance to fetal brain damage in phenylketonuria. Cancer. Res., 54: 891-895, 1994.
    • (1994) Cancer. Res. , vol.54 , pp. 891-895
    • Samid, D.1    Ram, Z.2    Hudgins, W.R.3    Shack, S.4    Liu, L.5    Walbridge, S.6    Oldfield, E.H.7    Myers, C.E.8
  • 24
    • 0027180685 scopus 로고
    • Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate
    • Samid, D., Sonsoles, S., and Myers, C. E. Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate. J. Clin. Invest., 91: 2288-2295, 1993.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2288-2295
    • Samid, D.1    Sonsoles, S.2    Myers, C.E.3
  • 25
    • 0028340043 scopus 로고
    • Effects of phenylacetate on cells from patients with B-chronic lymphocytic leukemia
    • Call, T. G., Stenson, M. J., and Witzig, T. E. Effects of phenylacetate on cells from patients with B-chronic lymphocytic leukemia. Leuk. Lymphoma, 14: 145-149, 1994.
    • (1994) Leuk. Lymphoma , vol.14 , pp. 145-149
    • Call, T.G.1    Stenson, M.J.2    Witzig, T.E.3
  • 27
    • 0029937059 scopus 로고    scopus 로고
    • Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate
    • Shack, S., Miller, A., Liu, L., Prasanna, P., Thibault, A., and Samid, D. Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate. Clin. Cancer Res., 2: 865-872, 1996.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 865-872
    • Shack, S.1    Miller, A.2    Liu, L.3    Prasanna, P.4    Thibault, A.5    Samid, D.6
  • 28
    • 0029999619 scopus 로고    scopus 로고
    • Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs
    • Pineau, T., Hudgins, R., Liu, L., Chen, L., Sher, T., Gonzalez, F. J., and Samid, D. Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs. Biochem. Pharmacol., 52: 659-667, 1996.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 659-667
    • Pineau, T.1    Hudgins, R.2    Liu, L.3    Chen, L.4    Sher, T.5    Gonzalez, F.J.6    Samid, D.7
  • 29
    • 0018835252 scopus 로고
    • Characterization of lymphoma-derived cell lines: Comparison of cell lines positive and negative for Epstein-Barr virus nuclear antigen. II. Surface markers
    • Magrath, I. T., Freeman, C. B., Pizzo, P., Gadek, J., Jaffe, E., Santaella, M., Hammer, C., Frank, M., Reaman, G., and Novikovs, L. Characterization of lymphoma-derived cell lines: comparison of cell lines positive and negative for Epstein-Barr virus nuclear antigen. II. Surface markers. J. Natl. Cancer Inst., 64: 477-483, 1980.
    • (1980) J. Natl. Cancer Inst. , vol.64 , pp. 477-483
    • Magrath, I.T.1    Freeman, C.B.2    Pizzo, P.3    Gadek, J.4    Jaffe, E.5    Santaella, M.6    Hammer, C.7    Frank, M.8    Reaman, G.9    Novikovs, L.10
  • 30
    • 0020028889 scopus 로고
    • Truncated μ chain in a Burkitt's lymphoma line (P3HR-1) and its fate in various hematopoietic somatic cell hybrids
    • Spira, G., Koide, N., Aman, P., Ber, R., and Klein, G. Truncated μ chain in a Burkitt's lymphoma line (P3HR-1) and its fate in various hematopoietic somatic cell hybrids. Immunohiology, 762: 199-209, 1982.
    • (1982) Immunohiology , vol.762 , pp. 199-209
    • Spira, G.1    Koide, N.2    Aman, P.3    Ber, R.4    Klein, G.5
  • 31
    • 0014304475 scopus 로고
    • Surface IgM-κ specificity on a Burkitt's lymphoma cell in vivo and in derived culture lines
    • Klein, E., Klein, G., Nadkarni, J. S., Nadkarni, J. J., Wigzell, H., and Clifford, P. Surface IgM-κ specificity on a Burkitt's lymphoma cell in vivo and in derived culture lines. Cancer Res., 28: 1300-1310, 1968.
    • (1968) Cancer Res. , vol.28 , pp. 1300-1310
    • Klein, E.1    Klein, G.2    Nadkarni, J.S.3    Nadkarni, J.J.4    Wigzell, H.5    Clifford, P.6
  • 32
    • 0023179989 scopus 로고
    • Variant sublines of the human B-lymphoma cells namalwa are at different stages of differentiation
    • Guy, K., Middleton, P. G., and Steel, C. M. Variant sublines of the human B-lymphoma cells Namalwa are at different stages of differentiation. Immunology, 61: 383-386, 1987.
    • (1987) Immunology , vol.61 , pp. 383-386
    • Guy, K.1    Middleton, P.G.2    Steel, C.M.3
  • 34
    • 0025907718 scopus 로고
    • Patterns of chromosomal breakpoint locations in Burkitt's lymphoma: Relevance to geography and Epstein-Barr virus association
    • Shiramizu, B., Barriga, F., Neequaye, J., Jafri, A., Dalla-Favera, R., Neri, A., Guttierez, M., Levine, P., and Magrath, I. Patterns of chromosomal breakpoint locations in Burkitt's lymphoma: relevance to geography and Epstein-Barr virus association. Blood, 77: 1516-1526, 1991.
    • (1991) Blood , vol.77 , pp. 1516-1526
    • Shiramizu, B.1    Barriga, F.2    Neequaye, J.3    Jafri, A.4    Dalla-Favera, R.5    Neri, A.6    Guttierez, M.7    Levine, P.8    Magrath, I.9
  • 35
    • 0023146392 scopus 로고    scopus 로고
    • DNA sequence of HLA-A11: Remarkable homology with HLA-A3 allows identification of residues involved in epitopes recognized by antibodies and T cells
    • Cowan, E. P., Jelachich, M. L., Biddison, W. E., and Coligan, J. E. DNA sequence of HLA-A11: remarkable homology with HLA-A3 allows identification of residues involved in epitopes recognized by antibodies and T cells. Immunogenetics, 25: 241-250.
    • Immunogenetics , vol.25 , pp. 241-250
    • Cowan, E.P.1    Jelachich, M.L.2    Biddison, W.E.3    Coligan, J.E.4
  • 36
    • 0024559913 scopus 로고
    • Expression of the BZLF1 latency-disrupting gene differs in standard and defective Epstein-Barr viruses
    • Taylor, N., Countryman, J., Rooney, C., Katz, D., and Miller, G. Expression of the BZLF1 latency-disrupting gene differs in standard and defective Epstein-Barr viruses. J. Virol., 63: 1721-1728, 1989.
    • (1989) J. Virol. , vol.63 , pp. 1721-1728
    • Taylor, N.1    Countryman, J.2    Rooney, C.3    Katz, D.4    Miller, G.5
  • 37
    • 0027538604 scopus 로고
    • Replicative viral DNA in Epstein-Barr virus associated Burkitt's lymphoma biopsies
    • Gutierrez, M. I., Bhatia, K., and Magrath, I. Replicative viral DNA in Epstein-Barr virus associated Burkitt's lymphoma biopsies. Leuk. Res., 17: 285-289, 1993.
    • (1993) Leuk. Res. , vol.17 , pp. 285-289
    • Gutierrez, M.I.1    Bhatia, K.2    Magrath, I.3
  • 38
    • 0025324027 scopus 로고
    • Different Epstein-Barr virus-B cell interactions in phenotypically distinct clones of a Burkitt's lymphoma cell line
    • Gregory, C. D., Rowe, M., and Rickinson, A. B. Different Epstein-Barr virus-B cell interactions in phenotypically distinct clones of a Burkitt's lymphoma cell line. J. Gen. Virol., 71: 1481-1495, 1990.
    • (1990) J. Gen. Virol. , vol.71 , pp. 1481-1495
    • Gregory, C.D.1    Rowe, M.2    Rickinson, A.B.3
  • 39
    • 0029143560 scopus 로고
    • Among 17 inducers of differentiation only sodium butyrate causes a permanent down-regulation of c-myc in Burkitt's lymphoma
    • Rottleb, C., Bornkamm, G. W., and Polack, A. Among 17 inducers of differentiation only sodium butyrate causes a permanent down-regulation of c-myc in Burkitt's lymphoma. Int. J. Cancer, 62: 697-702, 1995.
    • (1995) Int. J. Cancer , vol.62 , pp. 697-702
    • Rottleb, C.1    Bornkamm, G.W.2    Polack, A.3
  • 40
    • 0015298990 scopus 로고
    • Production of infective Epstein-Barr virus in a Burkitt's lymphoma cell line, P3HR-1
    • Nagoya, T., and Hinuma, Y. Production of infective Epstein-Barr virus in a Burkitt's lymphoma cell line, P3HR-1. Gann. 63: 87-93, 1972.
    • (1972) Gann , vol.63 , pp. 87-93
    • Nagoya, T.1    Hinuma, Y.2
  • 41
    • 0018693128 scopus 로고
    • Abortive expression of the Epstein-Barr virus (EBV) cycle in a variety of EBV DNA-containing cell lines, as reflected by nucleic acid hybridization in situ
    • Moar, M. H., and Klein, G. Abortive expression of the Epstein-Barr virus (EBV) cycle in a variety of EBV DNA-containing cell lines, as reflected by nucleic acid hybridization in situ. Int. J. Cancer, 24: 679-687, 1979.
    • (1979) Int. J. Cancer , vol.24 , pp. 679-687
    • Moar, M.H.1    Klein, G.2
  • 42
    • 0022895276 scopus 로고
    • The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation
    • Raab-Traub, N., and Flynn, K. The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation. Cell, 47: 883-889, 1986.
    • (1986) Cell , vol.47 , pp. 883-889
    • Raab-Traub, N.1    Flynn, K.2
  • 43
    • 0024437940 scopus 로고
    • Suppression of MHC class I gene expression by N-myc through enhancer inactivation
    • Lenardo, M., Rustgi, A. K., Schievella, A. R., and Bernards, R. Suppression of MHC class I gene expression by N-myc through enhancer inactivation. EMBO J., 8: 3351-3355, 1989.
    • (1989) EMBO J. , vol.8 , pp. 3351-3355
    • Lenardo, M.1    Rustgi, A.K.2    Schievella, A.R.3    Bernards, R.4
  • 45
    • 2442721694 scopus 로고    scopus 로고
    • Transcriptional up-regulation of γ-globin by phenylbutyrate and analogous aromatic fatty acids
    • Hudgins, W. R., Fibach, E., Safaya, S., Rieder, R. F., Miller, A. C., and Samid, D. Transcriptional up-regulation of γ-globin by phenylbutyrate and analogous aromatic fatty acids. Biochem. Pharmacol., 52: 1227-1233, 1996.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1227-1233
    • Hudgins, W.R.1    Fibach, E.2    Safaya, S.3    Rieder, R.F.4    Miller, A.C.5    Samid, D.6
  • 46
    • 0028840682 scopus 로고
    • Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-Azacytidine treatment: Evidence that demethylation at a single CpG site is crucial
    • Robertson, K. D., Hayward, D., Ling, P. D., Samid, D., and Ambinder, R. F. Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-Azacytidine treatment: evidence that demethylation at a single CpG site is crucial. Mol. Cell. Biol., 15: 6150-6159, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6150-6159
    • Robertson, K.D.1    Hayward, D.2    Ling, P.D.3    Samid, D.4    Ambinder, R.F.5
  • 47
    • 0001641450 scopus 로고    scopus 로고
    • The nuclear receptors PPARs as novel targets in differentiation therapy: Experience with phenylacetate and phenylbutyrate
    • Samid, D., Wels, M., Kulkarni, M., Liu, L., and Thibault, A., The nuclear receptors PPARs as novel targets in differentiation therapy: experience with phenylacetate and phenylbutyrate. Anticancer Res., 17: 3927-3928, 1997.
    • (1997) Anticancer Res. , vol.17 , pp. 3927-3928
    • Samid, D.1    Wels, M.2    Kulkarni, M.3    Liu, L.4    Thibault, A.5
  • 48
    • 3643104150 scopus 로고
    • Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
    • Warrell, R. P., He, L-Z., Richon, V., Calleja, E., and Pandolfi, P. P. Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. J. Natl. Cancer Inst., 90: 1621-1625, 1995.
    • (1995) J. Natl. Cancer Inst. , vol.90 , pp. 1621-1625
    • Warrell, R.P.1    He, L.-Z.2    Richon, V.3    Calleja, E.4    Pandolfi, P.P.5
  • 50
    • 0003218809 scopus 로고    scopus 로고
    • Improved hematopoiesis in patients with myelodysplastic syndromes and acute myeloid leukemia following administration of the putative differentiating agent sodium phenylbutyrate
    • Gore, S. D., Miller, C. B., Weng, L. J., Burks, K., Griffen, C. A., Chen, T. L., Burke, P. J., Grever, M., and Rowinsky, E. K. Improved hematopoiesis in patients with myelodysplastic syndromes and acute myeloid leukemia following administration of the putative differentiating agent sodium phenylbutyrate. Blood, 88: 582a, 1996.
    • (1996) Blood , vol.88
    • Gore, S.D.1    Miller, C.B.2    Weng, L.J.3    Burks, K.4    Griffen, C.A.5    Chen, T.L.6    Burke, P.J.7    Grever, M.8    Rowinsky, E.K.9
  • 51
    • 24844450698 scopus 로고    scopus 로고
    • A phase I and clinical pharmacokinetic study of intravenous sodium phenylbutyrate, given on a twice daily infusion schedule
    • Young, C., Malkin, M., Lieberman, F., Tong, W., Krol, G., and Fleischauer, A. A phase I and clinical pharmacokinetic study of intravenous sodium phenylbutyrate, given on a twice daily infusion schedule. Proc. Am. Soc. Clin. Oncol., 16: 255a, 1997.
    • (1997) Proc. Am. Soc. Clin. Oncol. , vol.16
    • Young, C.1    Malkin, M.2    Lieberman, F.3    Tong, W.4    Krol, G.5    Fleischauer, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.