Transcriptional upregulation of γ-globin by phenylbutyrate and analogous aromatic fatty acids

Biochemical Pharmacology

Volumn 52, Issue 8, 1996, Pages 1227-1233

  Hudgins, W Robert ^b   Fibach, Eitan ^b   Safaya, Surinder ^b   Rieder, Ronald F ^b   Miller, Alexandra C ^b   Samid, Dvorit ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b NONE

Author keywords

aromatic fatty acids; butyrate responsive promoter; erythroid precursor; hemoglobin F; phenylbutyrate; hemoglobinopathies

Indexed keywords

3 PHENOXYPROPIONIC ACID; 4 PHENYLBUTYRAMIDE; 4 PHENYLBUTYRIC ACID; 5 PHENYLPENTANOIC ACID; AROMATIC COMPOUND; BENZYLOXYACETIC ACID; BENZYLTHIOGLYCOLIC ACID; FATTY ACID; GAMMA GLOBIN; HEMOGLOBIN F; HYDROCINNAMIC ACID; MESSENGER RNA; PHENYLACETIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BETA THALASSEMIA; CELL STRAIN K 562; CONTROLLED STUDY; DRUG MECHANISM; ERYTHROID CELL; ERYTHROLEUKEMIA CELL; GENE ACTIVATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; SICKLE CELL ANEMIA; STRUCTURE ACTIVITY RELATION;

EID: 2442721694     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00476-5     Document Type: Article

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