Identification of SK-951, a novel benzofuran derivative, as an agonist to 5-HT4 receptors

Japanese Journal of Pharmacology

Volumn 79, Issue 2, 1999, Pages 203-212

  Takeda, Motohiro ^a   Tsukamoto, Katsura ^a   Mizutani, Yuka ^a   Suzuki, Tsunemasa ^a   Taniyama, Kohtaro ^b  

^a SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

5 HT4 receptor; Benzofuran derivative; Guinea pig ileum; Rat esophagus; SK 951

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; 4 AMINO 5 CHLORO 2,3 DIHYDRO 2 METHYL N [2 (8 PYRROLIZIDINYL)ETHYL]BENZO[B]FURAN 7 CARBOXAMIDE; ACETYLCHOLINE; BENZOFURAN DERIVATIVE; CARBACHOL; CISAPRIDE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; SEROTONIN 1 RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; SEROTONIN 4 AGONIST; SEROTONIN 4 RECEPTOR; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; DRUG STRUCTURE; ELECTROSTIMULATION; ESOPHAGUS MUCOSA; ESOPHAGUS MUSCLE; GUINEA PIG; ILEUM; ILEUM CONTRACTION; MALE; MUSCLE RELAXATION; MYENTERIC PLEXUS; NONHUMAN; RADIORECEPTOR ASSAY;

EID: 0033024317     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.79.203     Document Type: Article

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