Estrogenic stimulation of hypothalamic-limbic system metabolism in ageing diabetic C57BL/KsJ mice

Neuroendocrinology

Volumn 69, Issue 6, 1999, Pages 424-429

  Garris, David R ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Ageing; Diabetes; Gonadal steroids; Limbic system; Mouse

Indexed keywords

ESTROGEN; GLUCOSE;

AGING; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; HORMONAL REGULATION; HYPOTHALAMUS; LIMBIC SYSTEM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPTUM PELLUCIDUM;

EID: 0033021052     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054445     Document Type: Article

References (33)

1. Bestetti G, Rossi GL: Hypothalamic lesions in rats with long-term streptozotocin-induced diabetes mellitus: A semiquantitative light and electron microscopic study. Acta Neuropathol 1980;52:119-127.
2. Bray GA, York DA: Hypothalamic and genetic obesity in experimental animals: An autonomic and endocrine hypothesis. Physiol Rev 1979; 59:719-809.
3. DeJong RN: CNS manifestation of diabetes mellitus. Postgrad Med 1977;61:101-107.
4. Garris DR: Obese (ob/ob) and diabetes (db/db) mutations: Two factors modulating brain and peripheral tissue uptake of estradiol in C57BL/KsJ mice. Dev Brain Res 1987;35:153-157.
5. Garris DR: Morphometric analysis of obesity (ob/ob) and diabetes (db/db) associated hypothalamic neuronal degeneration in C57BL/KsJ mice. Brain Res 1989;501:162-170.
6. Garris DR, Diani AR, Smith C, Gerritsen G: Depopulation of the ventromedial hypothalamic nucleus in the diabetic Chinese hamster. Acta Neuropathol 1982;56:63-66.
7. Garris DR, Smith C, Davis D, Diani A, Gerritsen G: Morphometric evaluation of the hypothalamic-ovarian axis of the ketonuric, diabetic Chinese hamster: Relationship to the reproductive cycle. Diabetologia 1982;23:275-279.
8. Olsson Y, Soderbergh JS, Sourander P, Angervail L: A patho-anatomical study of the central and periphal nervous system in diabetes of early onset and long duration. Pathol Eur 1968;3: 62-79.
9. Smith-West C, Garris DR: Diabetes-associated hypothalamic neuronal depopulation in the aging Chinese hamster. Dev Brain Res 1983; 9:385-389.
10. Coleman DL: Diabetes-obesity syndromes in mice. Diabetes 1982;31(suppl 1):1-6.
11. Coleman DL: Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978;14:141-148.
12. Garris DR, West RL, Coleman DL: Morphometric analysis of medial basal hypothalamic neuronal degeneration in diabetes (db/db) mutant C57BL/KS mice: Relation to age and hyperglycemia. Dev Brain Res 1985;20:161-168.
13. Garris DR, Coleman DL, Morgan CR: Age and diabetes-related changes in glucose uptake and estradiol accumulation in the C57BL/KsJ mouse. Diabetes 1985;34:47-52.
14. Garris DR, Michael ME; Regional glucose uptake in genetically diabetic C57BL/KsJ mice: Modulation by the opiate antagonist, Nalmefene. Brain Res 1988;445:262-267.
15. Garris DR, Williams SK, Coleman DL, Morgan CR: Glucose utilization by the mouse brain: Influence of age and diabetes. Dev Brain Res 1984;15:141-146.
16. Vannucci SJ, Gibbs EM, Simpson IA: Glucose utilization and glucose transporter proteins GLUT-1 and GLUT-3 in brains of diabetic (db/db) mice. Am J Physiol 1997;272:E267-E274.
17. Garris DR: Age and diabetes-associated alterations in regional brain norepinephrine concentrations and adrenergic receptor populations in C57BL/KsJ mice. Dev Brain Res 1990; 51:161-166.
18. Garris DR: Developmental and regional changes in brain norepinephrine levels in diabetic C57BL/KsJ mice: Effects of estradiol and progesterone. Dev Brain Res 1995;89:314-319.
19. Garris DR: Depressed progesterone accumulation by brain and peripheral tissues of diabetic C57BL/KsJ mice: Normalization by estrogen therapy. Horm Res 1987;25:37-48.
20. Garris DR, Coleman DL: Diabetes-associated changes in estradiol accumulation in the ageing C57BL/KsJ mouse brain. Neurosci Lett 1985; 49:285-290.
21. Johnson MD, Crowley WR: Effects of opiate antagonists on serotonin turnover and on luteinizing hormone and prolactin secretion in estrogen-or morphine-treated rats. Neuroendocrinology 1984;38:322-327.
22. Garris DR: Effects of diabetes (db/db) mutation on brain and peripheral tissue insulin receptor binding in C57BL/KsJ mice: Modulating actions of estradiol and progesterone. Med Sci Res 1988;16:347-348.
23. Coleman DL, Leiter EH, Applezqeig N: Therapeutic effects of dehydroepiandrosterone metabolites in diabetic mutant mice (C57BL/KsJ-db/db). Endocrinology 1984;115:239-243.
24. Coleman DL, Leiter EH, Schwezer RW: Therapeutic effects of dehydroepiandrosterone (DHEA) in diabetic mice. Diabetes 1982;31: 830-833.
25. Coleman DL, Schwizer RW, Leiter EH: Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice. Diabetes 1984;33:26-32.
26. Garris DR: Diabetes-associated alteration in uterine structure in the C57BL/KsJ mouse: Relationship to changes in estradiol accumulation, circulating ovarian steroid levels and age. Anat Rec 1985;211:414-419.
27. Garris DR, Williams SK, West L: Morphometric evaluation of diabetes-associated, ovarian atrophy in the C57BL/KS mouse: Relationship to age and ovarian function. Anat Rec 1985; 211:434-443.
28. 3H-estradiol; in Stumpf WE, Grant LD (eds): Anatomical Neuroendocrinology. Basel, Karger, 1974, pp 82-103.
29. Benzo CA: The hypothalamus and blood glucose regulation. Life Sci 1983;32:2509-2515.
30. Bhanoot R, Wilkinson M: The inhibitory effect of opiates on gonadotrophin secretion is dependent upon gonadal steroids. J Endocrinol 1984; 102:133-141.
31. 3H]estradiol in diabetic rats deprived of insulin: Time course and metabolic correlates. Neuroendocrinology 1981;33:1-6.
32. Rapport SI, Duara R, London ED, Margolin RA, Schwartz M, Cutler NR, Partanen M, Schinowara NC: Glucose metabolism of the aging nervous system; in Samuel D (ed): Aging of the Brain. New York, Raven Press, 1983, pp 111-121.
33. McCall AM: The impact of diabetes on the CNS. Diabetes 1992;41:557-570.