Brachyury (T) expression in embryonal carcinoma P19 cells resembles its expression in primitive streak and tail-bud but not that in notochord

Development Growth and Differentiation

Volumn 41, Issue 3, 1999, Pages 253-264

  Yamaguchi, Hirotake ^a   Niimi, Tomoaki ^a   Kitagawa, Yasuo ^a   Miki, Kiyoshi ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Brachyury; Embryonal carcinoma; Gene expression; Mesoderm; Transgenic mouse

Indexed keywords

DIMETHYL SULFOXIDE; GENE PRODUCT; PROTEIN BRACHYURY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; EMBRYO; EMBRYONAL CARCINOMA; FEMALE; GENE EXPRESSION; IN SITU HYBRIDIZATION; MALE; MESODERM; MOUSE; NONHUMAN; NOTOCHORD; PRIMITIVE STREAK; PROMOTER REGION; REPORTER GENE; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; CARCINOMA, EMBRYONAL; DNA PRIMERS; DNA-BINDING PROTEINS; FETAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, TRANSGENIC; NOTOCHORD; PROMOTER REGIONS (GENETICS); T-BOX DOMAIN PROTEINS; TAIL; TRANSCRIPTION FACTORS;

ANIMALIA; MUS MUSCULUS;

EID: 0033020232     PISSN: 00121592     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-169X.1999.413427.x     Document Type: Article

References (43)

1. Amaya, E., Musci, T. J. & Kirschner, M. W. 1991. Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.
2. Artzt, K., Cookingham, J. & Bennett, D. 1987. A new mutation (t-int) interacts with the mutations of the mouse T/t complex that affect the tail. Genetics 116, 601-605.
3. Beddington, R. S. P. 1994. Induction of a second neural axis by the mouse node. Development 120, 613-620.
4. Chomczynski, P. & Sacchi, N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
5. Clements, D., Taylor, H. C., Herrmann, B. G. & Stott, D. 1996. Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation. Mech. Dev. 56, 139-149.
6. Corbo, J. C., Levine, M. & Zeller, R. W. 1997. Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis. Development 124, 589-602.
7. Dobrovolskaia-Zavadskaia, N. 1927. Sur la mortification spontanee de la queuw chez la spuris nouveau et sur l'existence d'un caractere (facteur) hereditaire non viable. Compr. Soc. Biol. 97, 114-119.
8. Dunn, L. C. & Caspari, E. 1945. A case of neighboring loci with similar effects. Genetics 30, 543-568.
9. Edwards, M. K. S. & McBurney, M. W. 1983. The concentration of retinoic acid determines the differentiated cell types formed by a teratocarcinoma cell line. Dev. Biol. 98, 187-191.
10. Fujiwara, S., Corbo, J. C. & Levin, M. 1998. The snail repressor establishes a muscle/notochord boundary in the Ciona embryo. Development 125, 2511-2520.
11. Halpern, M. E., Ho, R. K., Walker, C. & Kimmel, C. B. 1993. Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation. Cell 75, 99-111.
12. Hemmati-Brivanlou, A., Frank, D., Bolce, M. E., Brown, B. D., Sive, H. L. & Harland, R. M. 1990. Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization. Development 110, 325-330.
13. TWIS mutant embryos. Development 113, 913-917.
14. Herrmann, B. G. 1996. The mouse Brachyury (T) gene. Semin. Dev. Biol. 6, 385-394.
15. Herrmann, B. G., Labeit, S., Poustka, A., King, T. R. & Lehrach, H. 1990. Cloning of the T required in mesoderm formation in the mouse. Nature 343, 617-622.
16. Isaacs, H. V., Pownall, M. E. & Slack, J. M. W. 1994. eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J. 13, 4469-4481.
17. Isaacs, H. V., Pownall, M. E. & Slack, J. M. W. 1995. eFGF is expressed in the dorsal midline of Xenopus laevis. Int. J. Dev. Biol. 39, 375-379.
18. Justice, M. J. & Bode, V. C. 1986. Introduction of new mutations in a mouse t-haplotype using ethylnitrosourea mutagenesis. Genet. Res. 47, 187-192.
19. Kim, D. W., Uetsuki, T., Kaziro, Y., Yamaguchi, N. & Sugano, S. 1990. Use of the human elongation factor 1-α promoter as a versatile and efficient expression system. Gene 91, 217-224.
20. Kispert, A. & Herrmann, B. G. 1994, Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos. Dev. Biol. 161, 179-193.
21. Kispert, A., Ortner, H., Cooke, J. & Herrmann, B. G. 1995. The chick Brachyury gene: Developmental expression pattern and response to axial induction by localized activin. Dev. Biol. 168, 406-415.
22. Knezevic, V., De Santo, R. & Mackem, S. 1997. Two novel chick T-box genes related to mouse Brachyury are expressed in different, non-overlapping mesodermal domains during gastrulation. Development 124, 411-419.
23. LaBonne, C. & Whitman, M. 1994. Mesoderm induction by activin requires FGF-mediated intracellular signals. Development 120, 463-472.
24. Latinkic, R. V., Umbhauer, M., Neal, K. A., Lerchner, W., Smith, J. C. & Cunliffe, V. 1997. The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentration of activin by paired-type homeodomain proteins. Genes Dev. 11, 3265-3276.
25. McBurney, M. W., Jones-Villeneuve, E. M. V., Edwards, M. K. S. & Anderson, P. J. 1982. Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line. Nature 298, 165-167.
26. MacNicol, A. M., Muslin, A. J. & Williams, L. T. 1993. Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF. Cell 73, 571-583.
27. Nakatsuji, N., Snow, M. L. H. & Wylie, C. C. 1986. Cinemicrographic study of the cell movement in the primitive-streak-stage mouse embryo. J. Embryol. Exp. Morphol. 96, 99-109.
28. Pruitt, S. C. 1994. Primitive streak mesoderm-like cell lines expressing Pax-3 and Hox gene autoinducing activities. Development 120, 37-47.
29. Rennebeck, G. M., Lader, E., Chen, Q. et al. 1995. Is there a Brachyury the Second? Analysis of a transgenic mutation involved in notochord maintenance in mice. Dev. Biol. 172, 206-217.
30. Schmidt, C., Wilson, V., Stott, D. & Beddington, R. S. P. 1997. T promoter activity in the absence of functional T protein during axis formation and elongation in the mouse. Dev. Biol. 189, 161-173.
31. Schulte-Merker, S., Hammerschmidt, M., Beuchle, D., Cho, K. W., De Robertis, E. M. & Nüsslein-Volhard, C. 1994a. Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos. Development 120, 843-852.
32. Schulte-Merker, S., Ho, R. K., Herrmann, B. G. & Nüsslein-Volhard, C. 1992. The protein product of the zebrafish homologue of the mouse T is expressed in nuclei of the germ ring and the notochord of the early embryo. Development 116, 1021-1032.
33. Schulte-Merker, S. & Smith, J. C. 1995. Mesoderm formation in response to Brachyury requires FGF signaling. Curr. Biol. 5, 62-67.
34. Schulte-Merker, S., van Eeden, F. J. M., Halpern, M. E., Kimmel, C. B. & Nüsslein-Volhard, C. 1994b. no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development 120, 1009-1015.
35. Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. & Herrmann, B. G. 1991. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.
36. Stott, D., Kispert, A. & Herrmann, B. G. 1993. Rescue of the tail defect of Brachyury mice. Genes Dev. 7, 197-203.
37. Taniguchi, Y., Miki, K. & Kitagawa, Y. 1993. Transient gene expression by SV40 promoter characterizes sequential differentiation of embryonal carcinoma F9 cells into primitive and visceral endoderm. Exp. Cell Res. 204, 286-294.
38. Uetsuki, T., Naito, A., Nagata, S. & Kaziro, Y. 1989. Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor 1-α. J. Biol. Chem. 264, 5791-5798.
39. Vidricaire, G., Jardine, K. & McBurney, M. W. 1994. Expression of the Brachyury gene during mesoderm development in differentiating embryonal carcinoma cell cultures. Development 120, 115-122.
40. Wilkinson, D. G., Bhatt, S. & Herrmann, B. G. 1990. Expression pattern of the mouse T gene and its role on mesoderm formation. Nature 343, 657-659.
41. Yasuo, H., Kobayashi, M., Shimauchi, Y. & Satoh, N. 1996. The ascidian genome contains another T-domain gene that is expressed in differentiating muscle and the tip of the tail of the embryo. Dev. Biol. 180, 773-779.
42. Yasuo, H. & Satoh, N. 1993. Function of vertebrate T gene. Nature 364, 582-583.
43. Yasuo, H. & Satoh, N. 1998. Conservation of the developmental role of Brachyury in notochord formation in a urochordate, the ascidian Balocynthia roretzi. Dev. Biol. 200, 158-170.