메뉴 건너뛰기




Volumn 27, Issue 6, 1999, Pages 736-740

Presystemic metabolism of albendazole: Experimental evidence of an efflux process of albendazole sulfoxide to intestinal lumen

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE; ALBENDAZOLE SULFOXIDE; CYTOCHROME P450; POLYSORBATE 80; TAUROCHOLIC ACID;

EID: 0033020066     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (34)

References (36)
  • 2
    • 0025908796 scopus 로고
    • In vivo intestinal metabolism of 7-ethoxycoumarin in the rat: Production and distribution of phase I and II metabolites in the isolated, perfused intestinal loop
    • Albers R and Rosenberg DW (1991) In vivo intestinal metabolism of 7-ethoxycoumarin in the rat: Production and distribution of phase I and II metabolites in the isolated, perfused intestinal loop. Toxicol Appl Pharmacol 109:507-513.
    • (1991) Toxicol Appl Pharmacol , vol.109 , pp. 507-513
    • Albers, R.1    Rosenberg, D.W.2
  • 3
    • 0021171120 scopus 로고
    • Simultaneous determination of albendazole and its principal metabolites in plasma by normal phase high-performance liquid chromatography
    • Alvinerie M and Galtier P (1984) Simultaneous determination of albendazole and its principal metabolites in plasma by normal phase high-performance liquid chromatography. J Pharm Biomed Anal 2:73-79.
    • (1984) J Pharm Biomed Anal , vol.2 , pp. 73-79
    • Alvinerie, M.1    Galtier, P.2
  • 4
    • 0016817805 scopus 로고
    • Guinea pig liver microsomal UDP-glucuronyltransferase: Compartmented or phospholipid-constrained?
    • Berry C, Stellon A and Hallinan T (1975) Guinea pig liver microsomal UDP-glucuronyltransferase: Compartmented or phospholipid-constrained? Biochim Biophys Acta 403:335-344.
    • (1975) Biochim Biophys Acta , vol.403 , pp. 335-344
    • Berry, C.1    Stellon, A.2    Hallinan, T.3
  • 5
    • 0028880580 scopus 로고
    • First-pass accumulation of salicylic acid in gut tissue after absorption in anesthetized rat
    • Choi YM, Chung SM and Chiou WL (1995) First-pass accumulation of salicylic acid in gut tissue after absorption in anesthetized rat. Pharm Res 12:1323-1327.
    • (1995) Pharm Res , vol.12 , pp. 1323-1327
    • Choi, Y.M.1    Chung, S.M.2    Chiou, W.L.3
  • 7
    • 0026032166 scopus 로고
    • Comparative enantioselectivity in the sulfoxidation of albendazole in man, dogs and rats
    • Delatour P, Benoit E, Bessé S and Boukraa A (1991) Comparative enantioselectivity in the sulfoxidation of albendazole in man, dogs and rats. Xenobiotica 21:217-221.
    • (1991) Xenobiotica , vol.21 , pp. 217-221
    • Delatour, P.1    Benoit, E.2    Bessé, S.3    Boukraa, A.4
  • 8
    • 0030858478 scopus 로고    scopus 로고
    • Effects of albendazole, fumagillin, and TNP-470 on microsporidial replication in vitro
    • Didier ES (1997) Effects of albendazole, fumagillin, and TNP-470 on microsporidial replication in vitro. Antimicrob Agents Chemother 41:1541-1546.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1541-1546
    • Didier, E.S.1
  • 9
  • 10
    • 0027404182 scopus 로고
    • Rat small intestinal cytochromes P450 probed by warfarin metabolism
    • Fasco MJ, Silkworth JB, Dunbar DA and Kaminsky LS (1993) Rat small intestinal cytochromes P450 probed by warfarin metabolism. Mol Pharmacol 43:226-233.
    • (1993) Mol Pharmacol , vol.43 , pp. 226-233
    • Fasco, M.J.1    Silkworth, J.B.2    Dunbar, D.A.3    Kaminsky, L.S.4
  • 11
    • 0022592940 scopus 로고
    • In vitro sulfoxidation of albendazole by ovine liver microsomes: Assay and frequency of various xenobiotics
    • Galtier P, Alvinerie M and Delatour P (1986) In vitro sulfoxidation of albendazole by ovine liver microsomes: Assay and frequency of various xenobiotics. Am J Vet Res 47:447-450.
    • (1986) Am J Vet Res , vol.47 , pp. 447-450
    • Galtier, P.1    Alvinerie, M.2    Delatour, P.3
  • 13
    • 0025827880 scopus 로고
    • Inducing effect of oxfendazole on cytochrome P450IA2 in rabbit liver. Consequences on cytochrome P450 dependent monooxygenases
    • Gleizes C, Eeckhoutte C, Pineau T, Alvinerie M and Galtier P (1991) Inducing effect of oxfendazole on cytochrome P450IA2 in rabbit liver. Consequences on cytochrome P450 dependent monooxygenases. Biochem Pharmacol 41:1813-1820.
    • (1991) Biochem Pharmacol , vol.41 , pp. 1813-1820
    • Gleizes, C.1    Eeckhoutte, C.2    Pineau, T.3    Alvinerie, M.4    Galtier, P.5
  • 14
    • 0024406112 scopus 로고
    • Dosage-dependent absorption of cadmium in the rat intestine measured in situ
    • Goon D and Klaassen CD (1989) Dosage-dependent absorption of cadmium in the rat intestine measured in situ. Toxicol Appl Pharmacol 100:41-50.
    • (1989) Toxicol Appl Pharmacol , vol.100 , pp. 41-50
    • Goon, D.1    Klaassen, C.D.2
  • 15
    • 0001684352 scopus 로고
    • Surfactant interactions with biomembranes and proteins
    • Jones MN (1992) Surfactant interactions with biomembranes and proteins. Chem Society Rev (002):127-136.
    • (1992) Chem Society Rev , vol.2 , pp. 127-136
    • Jones, M.N.1
  • 16
    • 0014788109 scopus 로고
    • Effect of bile salts on the gastrointestinal absorption of drugs. II. Mechanism of the enhancement of the intestinal absorption of sulfaguanidine by bile salts
    • Kakemi K, Sezaki H, Konishi R, Kimura T and Okita A (1970) Effect of bile salts on the gastrointestinal absorption of drugs. II. Mechanism of the enhancement of the intestinal absorption of sulfaguanidine by bile salts. Chem Pharm Bull 18:1034-1039.
    • (1970) Chem Pharm Bull , vol.18 , pp. 1034-1039
    • Kakemi, K.1    Sezaki, H.2    Konishi, R.3    Kimura, T.4    Okita, A.5
  • 17
    • 0029931821 scopus 로고    scopus 로고
    • Albendazole chemotherapy for treatment of diarrhoea in patients with AIDS in Zambia: A randomised double blind controlled trial
    • Kelly P, Lungu F, Keane E, Baggaley R, Kazembe F, Pobee J and Farthing M (1996) Albendazole chemotherapy for treatment of diarrhoea in patients with AIDS in Zambia: A randomised double blind controlled trial. Br Med J 312:1187-1191.
    • (1996) Br Med J , vol.312 , pp. 1187-1191
    • Kelly, P.1    Lungu, F.2    Keane, E.3    Baggaley, R.4    Kazembe, F.5    Pobee, J.6    Farthing, M.7
  • 19
    • 0020082753 scopus 로고
    • Mouse liver microsomal hexose-6-phosphate dehydrogenase. NADPH generation and utilization in monooxygenation reactions
    • Kulkarni AP and Hodgson E (1982) Mouse liver microsomal hexose-6-phosphate dehydrogenase. NADPH generation and utilization in monooxygenation reactions. Biochem Pharmacol 31:1131-1137.
    • (1982) Biochem Pharmacol , vol.31 , pp. 1131-1137
    • Kulkarni, A.P.1    Hodgson, E.2
  • 20
    • 0029836098 scopus 로고    scopus 로고
    • Dietary indole-3-carbinol inhibits FMO activity and the expression of flavin-containing tnonooxygenase form 1 in rat liver and intestine
    • Larsen-Su S and Willians DE (1996) Dietary indole-3-carbinol inhibits FMO activity and the expression of flavin-containing tnonooxygenase form 1 in rat liver and intestine. Drug Metab Dispos 24:927-931.
    • (1996) Drug Metab Dispos , vol.24 , pp. 927-931
    • Larsen-Su, S.1    Willians, D.E.2
  • 21
    • 0026939323 scopus 로고
    • Investigations on metabolism of albendazole in the isolated perfused gut of rats
    • Lawrenz VA, Eglit S and Kroker R (1992) Investigations on metabolism of albendazole in the isolated perfused gut of rats. Dtsch Tieräztl Wschr 99:416-418.
    • (1992) Dtsch Tieräztl Wschr , vol.99 , pp. 416-418
    • Lawrenz, V.A.1    Eglit, S.2    Kroker, R.3
  • 22
    • 0027178256 scopus 로고
    • Dose-dependent intestinal absorption and significant intestinal excretion (exsorption) of the beta-blocker pafenolol in the rat
    • Lennernäs H and Regårdh CG (1993) Dose-dependent intestinal absorption and significant intestinal excretion (exsorption) of the beta-blocker pafenolol in the rat. Pharm Res (NY) 10:727-731.
    • (1993) Pharm Res (NY) , vol.10 , pp. 727-731
    • Lennernäs, H.1    Regårdh, C.G.2
  • 24
    • 0015253752 scopus 로고
    • Nonabsorbed indicators: A comparison of phenol red and inulin-14C and effects of perfusion technique
    • Miller DL and Schedl HP (1972) Nonabsorbed indicators: a comparison of phenol red and inulin-14C and effects of perfusion technique. Gastroenterology 62:48-55.
    • (1972) Gastroenterology , vol.62 , pp. 48-55
    • Miller, D.L.1    Schedl, H.P.2
  • 25
    • 0020505032 scopus 로고
    • Effects of surfactants on the gastrointestinal absorption of beta-lactam antibiotics in rats
    • Miyamoto E, Tsuji A and Yamana T (1983) Effects of surfactants on the gastrointestinal absorption of beta-lactam antibiotics in rats. J Pharm Sci 72:651-654.
    • (1983) J Pharm Sci , vol.72 , pp. 651-654
    • Miyamoto, E.1    Tsuji, A.2    Yamana, T.3
  • 26
    • 0028812229 scopus 로고
    • Chiral sulfoxidation of albendazole by the flavin adenine dinucleotide-containing and cytochrome P450-dependent monooxygenases from rat liver microsomes
    • Moroni P, Buronfosse T, Longin-Sauvageon C, Delatour P and Benoit E (1995) Chiral sulfoxidation of albendazole by the flavin adenine dinucleotide-containing and cytochrome P450-dependent monooxygenases from rat liver microsomes. Drug Metab Dispos 23:106-165.
    • (1995) Drug Metab Dispos , vol.23 , pp. 106-165
    • Moroni, P.1    Buronfosse, T.2    Longin-Sauvageon, C.3    Delatour, P.4    Benoit, E.5
  • 27
    • 0021337092 scopus 로고
    • Intestinal absorption and metabolism of 6-mercaptopurine in the rat small intestine
    • Ravis W, Wang JS and Feldman S (1983) Intestinal absorption and metabolism of 6-mercaptopurine in the rat small intestine. Biochem Pharmacol 33:443-448.
    • (1983) Biochem Pharmacol , vol.33 , pp. 443-448
    • Ravis, W.1    Wang, J.S.2    Feldman, S.3
  • 28
    • 0031931325 scopus 로고    scopus 로고
    • Influence of surfactants on oral bioavailability of albendazole based on the formation of the sulphoxide metabolites in rats
    • Redondo PA, Alvarez AI, García JL, Villaverde C and Prieto JG (1998) Influence of surfactants on oral bioavailability of albendazole based on the formation of the sulphoxide metabolites in rats. Biopharm Drug Dispos 19:65-70.
    • (1998) Biopharm Drug Dispos , vol.19 , pp. 65-70
    • Redondo, P.A.1    Alvarez, A.I.2    García, J.L.3    Villaverde, C.4    Prieto, J.G.5
  • 29
    • 0029950230 scopus 로고    scopus 로고
    • Structural requirements for the induction of cytochromes P450 by benzimidazole anthelmintic derivatives in cultures rabbit hepatocytes
    • Rey-Grobellet X, Ferre N, Eeckhoutte C, Larrieu G, Pineau T and Galtier P (1996) Structural requirements for the induction of cytochromes P450 by benzimidazole anthelmintic derivatives in cultures rabbit hepatocytes. Biochem Biophys Res Commun 220:789-794.
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 789-794
    • Rey-Grobellet, X.1    Ferre, N.2    Eeckhoutte, C.3    Larrieu, G.4    Pineau, T.5    Galtier, P.6
  • 30
    • 0023870683 scopus 로고
    • Inducing effect of albendazole on rat liver drug-metabolizing enzymes and metabolite pharmacokinetics
    • Souhaili-El Amri H, Fargetton X, Benoit E, Totis M and Batt AM (1988) Inducing effect of albendazole on rat liver drug-metabolizing enzymes and metabolite pharmacokinetics. Toxicol Appl Pharmacol 92:141-149.
    • (1988) Toxicol Appl Pharmacol , vol.92 , pp. 141-149
    • Souhaili-El Amri, H.1    Fargetton, X.2    Benoit, E.3    Totis, M.4    Batt, A.M.5
  • 32
    • 0026644535 scopus 로고
    • Drug metabolism by cytochromes P450 in the liver and small bowel
    • Watkins PB (1992) Drug metabolism by cytochromes P450 in the liver and small bowel. Gastroenterol Clin North Am 10:511-526.
    • (1992) Gastroenterol Clin North Am , vol.10 , pp. 511-526
    • Watkins, P.B.1
  • 33
    • 0023588109 scopus 로고
    • Identification of glucocorticoid-inducible cytochromes P450 in the intestinal mucosa of rats and man
    • Watkins PB, Wrighton SA, Schuetz EG, Molowa DT and Guzelian PS (1987) Identification of glucocorticoid-inducible cytochromes P450 in the intestinal mucosa of rats and man. J Clin Invest 80:1029-1036.
    • (1987) J Clin Invest , vol.80 , pp. 1029-1036
    • Watkins, P.B.1    Wrighton, S.A.2    Schuetz, E.G.3    Molowa, D.T.4    Guzelian, P.S.5
  • 34
    • 0015919572 scopus 로고
    • Intestinal epithelial cell surface membrane glycoprotein synthesis I. An indicator of cellular differentiation
    • Weiser MM (1973) Intestinal epithelial cell surface membrane glycoprotein synthesis I. An indicator of cellular differentiation. J Biol Chem 248:2536-2541.
    • (1973) J Biol Chem , vol.248 , pp. 2536-2541
    • Weiser, M.M.1
  • 35
    • 0021182258 scopus 로고
    • Drug elimination function of rat small intestine: Metabolism and intraluminal excretion
    • Yasuhara M, Kurosaki Y, Kimura T and Sezaki H (1984) Drug elimination function of rat small intestine: Metabolism and intraluminal excretion. Biochem Pharmacol 33:3131-3136.
    • (1984) Biochem Pharmacol , vol.33 , pp. 3131-3136
    • Yasuhara, M.1    Kurosaki, Y.2    Kimura, T.3    Sezaki, H.4
  • 36
    • 0030857439 scopus 로고    scopus 로고
    • Conformational change of cytochrome P450 1 A2 induced by phospholipids and detergents
    • Yun Ch, Song M and Kim H (1997) Conformational change of cytochrome P450 1 A2 induced by phospholipids and detergents. J Biol Chem 272:19725-19730.
    • (1997) J Biol Chem , vol.272 , pp. 19725-19730
    • Yun, Ch.1    Song, M.2    Kim, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.