No evidence for an altered mRNA expression or protein level of haematopoietic cell phosphatase in CD34+ bone marrow progenitor cells or mature peripheral blood cells in polycythaemia vera

European Journal of Haematology

Volumn 59, Issue 5, 1997, Pages 310-317

  Andersson, P ^a   LeBlanc, K ^b   Eriksson, B A ^a   Samuelsson, Jan ^b  

^a STOCKHOLM SÖDER HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Erythropoietin; Haematopoietic cell phosphatase; Polycythaemia vera; Polymerase chain reaction

Indexed keywords

CD34 ANTIGEN; COMPLEMENTARY DNA; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; MESSENGER RNA; PHOSPHATASE; POLYCLONAL ANTIBODY;

ARTICLE; BONE MARROW CELL; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MYELOPROLIFERATIVE DISORDER; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROTEIN CONTENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOTIC THROMBOCYTOPENIC PURPURA;

EID: 9844245132     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0609.1997.tb01692.x     Document Type: Article

References (45)

1. ADAMSON JW, FIALKOW PJ, MURPHY S, PRCHAL JF, STEINMANN L. Polycythemia vera: stem cell and probable clonal origin of the disease. N Engl J Med 1976: 295: 913-916.
2. GREGG XT, LIU Y, PRCHAL JT, GARTLAND GL, COOPER MD, PRCHAL JF. Clonality in myeloproliferative disorders. Blood 1996: 10 (suppl 1): 479a.
3. PRCHAL JF, AXELRAD AA. Bone marrow responses in polycythemia vera. N Engl J Med 1974: 290: 1382.
4. DAI CH, KRANTZ SB, DESSYPRIS EN, MEANS RT, HORN ST, GILBERT HS. Polycythemia vera II. Hypersensitivity of bone marrow erythroid. granulocyte-macrophage and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor. Blood 1992: 80: 891-899.
5. DAI CH, KRANTZ SB, KOURY ST, KOLLAR K. Polycythaemia vera. IV. Specific binding of stem cell factor to normal and polycythaemia vera highly purified erythroid progenitor cells. Br J Haematol 1994: 88: 497-505.
6. EMANUEL PD, EAVES CJ, BROUDY VC, et al. Familial and congenital polycythemia in three unrelated families. Blood 1992: 79: 3019-3030.
7. HESS G, ROSE P, GAMM H, PAPADILERIS S, HUBER C, SELIGER B. Molecular analysis of the erythropoietin receptor system in patients with polycythaemia vera. Br J Haematol 1994: 88: 794-802.
8. YI T, CLEVELAND JL, IHLE JN. Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoetic cells and localization to human chromosome 12p12-p13. Mol Cell Biol 1992: 12: 836-846.
9. YI T, ZHANG J, MIURA O, IHLE JN. Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epo-induced receptor tyrosine phosphorylation: identification of potential binding sites. Blood 1995: 85: 87-95.
10. YI T, IHLE JN. Association of hematopoietic cell phosphatase with c-kit after stimulation with c-kit ligand. Mol Cell Biol 1993: 13: 3350-3358.
11. YI T, MUI AL-F, KRYSTAL G, IHLE JN. Hematopoietic cell phospatase associates with the interleukin-3 (IL-3) receptor β-chain and down-regulates IL-3 induced tyrosine phosphorylation and mitogenesis. Mol Cell Biol 1993: 13: 7577.
12. VOGEL W, LAMMERS R, HUANG J, ULLRICH A. Activation of phosphotyrosine phosphatase by tyrosine phosphorylation. Science 1993: 259: 1611-1614.
13. TSUI HW, SIMINOVITCH KA, DE SOUZA L, TSUI FWL. Motheaten and viable motheaten mice have mutations in the hematopoietic cell phosphatase gene. Nat Genet 1993: 4: 124-129.
14. SCHULTZ LD, SCHWITZER PA, RAJAN TV, et al. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 1993: 73: 1445-1454.
15. VAN ZANT G, SCHULTZ L. Hematopoietic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev). Exp Hematol 1989: 17: 81-87.
16. BERLIN NI. Diagnosis and classification of the polycythemias. Semin Hematol 1975: 12: 339-351.
17. RINGERTZ B, PALMBLAD J, RÅDMARK O, MALMSTEN CL. Leukotriene induced neutrophil aggregation in vitro. FEBS Lett 1982: 147: 180-182.
18. MILTENYI S, MUELLER W, WEICHEL W, RADBRUCH A. High gradient magnetic cell separation with MACS. Cytometry 1990: 11: 231-238.
19. CHOMCZYNSKI P, SACCHI N. Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987: 162: 156-159.
20. DE WAAL MALEFYT R, ABRAMS J, BENNET B, FIGDOR CG, DE VRIES JE. Interleukin 10 inhibits cytokine synthesis by human monocytes: an autoregulatory role of interleukin 10 produced by monocytes. J Exp Med 1991: 174: 1209-1220.
21. LAEMMLI UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970: 227; 680.
22. LUCAS GS, PADUA RA, MASTERS GS, OSCIER DG, JACOBS A. The application of X-chromosome gene probes to the daignosis of myeloproliferative disease. Br J Haematol 1989: 72: 530-533.
23. ANGER B, JANSSEN JWG, SCHREZENMEIER H, HEHLMANN R, HEIMPEL H, BARTRAM CR. Clonal analysis of chronic myeloproliferative disorders using X-linked DNA polymorphism. Leuk Res 1990: 4: 258-261.
24. GILLILAND DG, BLANCHARD KL, LEVY J, PERRIN S, BUNN HF. Clonality in myeloproliferative disorders: analysis by means of the polymerase chain reaction. Proc Natl Acad Sci USA 1991: 88: 6448-6852.
25. RASKIND WH, JACOBSON R, MURPHY S, ADAMSON JW, FIALKOW PJ. Evidence for the involvement of B lymphoid cells in polycythemia vera and essential thrombocythemia. J Clin Invest 1985: 75: 1388-1390.
26. PRCHAL JT, GUAN YL, PRCHAL JF, BARANY F. Transcriptional analysis of the active X-chromosome in normal and clonal hematopoiesis. Blood 1993: 81: 269-271.
27. BERGER R, BERNHEIM A, LE CONIAT, et al. Chromosome studies in polycythemia vera patients. Cancer Genet Cytogenet 1984: 12: 217-233.
28. SWOLIN B, WEINFELD A, WESTIN J. A prospective long-term cytogenetic study in polycythemia vera in relation to treatment and clinical course.m Blood 1988: 72: 386-395.
29. ASIMAKOPOULOS F, GILBERT JGR, ALDRED MA, PEARSON TC, GREEN AR. Interstitial deletion constitutes the major mechanism for loss of heterozygosity on chromosome 20q in polycythemia vera. Blood 1996: 88: 2690-2698.
30. KRALOVICS R, SOKOL L, PRCHAL JF, PRCHAL JT. Identification of a putative molecular lesion of polycythemia vera phenotype. Blood 1995: 86: 733a.
31. PRCHAL JF, FISCHER MJ, PRCHAL JT, D'ANDREA AD. Abnormal growth of erythroid progenitors in polycythemia vera and in primary familial and congenital polycythemia. Blood 1992: 80: 214a.
32. CORREA PN, ESKINAZI D, AXELRAD AA. Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: studies in an improved serum-free medium. Blood 1994: 83: 99-112.
33. AKAHANE K, TOJO A, URABE A, TAKAKU F. Pure erythropoietic colony and burst formation in serum-free culture and their enhancement by insulin-like growth factor-1. Exp Hematol 1987: 15: 797-804.
34. GRELLIER P, CHANSON P, CASADEVALL N, ABBOUD S, SCHAISON G. Remission of polycythemia vera after surgical cure of acromegaly. Ann Intern Med 1996: 124: 495-496.
35. MIRZA AM, CORREA PN, AXELRAD AA. Increased basal and induced tyrosine phosphorylation of the insulin-like growth factor-1 receptor β subunit in circulating mononuclear cells of patients with polycythemia vera. Blood 1995: 86: 877-882.
36. WITTHUHN BA, QUELLE FW, SILVENNOINEN, et al. JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell 1993: 74: 227-236.
37. DUSANTER-FOURT I, CASADEVALL N, LACOMBE C, et al. Erythropoietin induces the tyrosine phosphorylation of its own receptor in human erythropoietin-responsive cells. J Biol Chem 1992: 267: 10670-10675.
38. KLINGMULLER U, LORENZ U, CANTLEY LC, NEEL BG, LODISH HF. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 1995: 80: 729-738.
39. DE LA CHAPELLE A, TRÄSKELIN A-L, JUVONEN E. Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc Natl Acad Sci, USA 1993: 90: 4495-4499.
40. GREGG XT, PRCHAL JT. Erythropoietin receptor mutations and human disease. Semin Hematol 1997: 34: 70-76.
41. FURUKAWA T, SAKANE M, OTSUKA T, et al. Primary familial polycythemia associated with novel point mutation in the erythropoietin receptor. Blood 1996: 88 (suppl 1): 569a.
42. HINSELWWOD S, ASIMAKAPOULOS FA, GILBERT JGR, et al. The gene encoding hematopietic cell phosphatase (SHP-1) is structurally and transcriptionally intact in polycythemia. Blood 1996: 88 (suppl 1): 96a.
43. LOCICERO R, SHEN Q, HARRIS K. The tyrosine phosphatase SHP-1 is deficient in polycythemia vera peripheral blood mononuclear cells. Blood 1996: 88 (suppl 1): 437a.
44. CHIN H, NAKAMURA N, KAMIYAMA R, MIYASAKA N, IHLE JN, MIURA O. Physical and functional interactions between Stat5 and the tyrosine-phosphorylated receptors for erythropoietin and interleukin-3. Blood 1996: 88: 4415-4425.
45. TIAN SS, TAPLEY P, SINCICH C, STEIN RB, ROSEN J, LAMB P. Multiple signalling pathways induced by granulocyte colony-stimulating factor involving activation of JAKs, STATS and/or STATS are required for regulation of three distinct classes of immediate early genes. Blood 1996: 88: 4435-4444.