Environmental modulation of oral treponeme virulence in a murine model

Infection and Immunity

Volumn 67, Issue 6, 1999, Pages 2783-2789

  Kesavalu, Lakshmyya ^a   Holt, Stanley C ^a   Ebersole, Jeffrey L ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIPYRIDINE; GALACTOSAMINE; IRON; PHENYLHYDRAZINE;

ABSCESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM ISOLATION; CONTROLLED STUDY; HOST; IRON CHELATION; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; TREPONEMA DENTICOLA;

EID: 0033017277     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.6.2783-2789.1999     Document Type: Article

References (54)

1. Blakemore, R. P., and E. Canale-Parola. 1976. Arginine catabolism by Treponema denticola. J. Bacteriol. 128:615-622.
2. Bramanti, T. E., and S. C. Holt. 1990. Iron-regulated outer membrane proteins in the periodontopathic bacterium, Bacteroides gingivalis. J. Biochem. Biophys. Res. Commun. 166:1146-1154.
3. Bramanti, T. E., and S. C. Holt. 1991. Roles of porphyrins and host iron transport proteins in regulation of growth of Porphyromonas gingivalis W50. J. Bacteriol. 173:7330-7339.
4. Bramanti, T. E., and S. C. Holt. 1992. Localization of a Porphyromonas gingivalis 26-kilodalton heat-modifiable, hemin-regulated surface protein which translocates across the outer membrane. J. Bacteriol. 174:5827-5839.
5. Cheng, S. L., R. Siboo, T. Chin Quee, J. L. Johnson, W. R. Mayberry, and E. C. S. Chan. 1985. Comparative study of six random oral spirochetes. Serological heterogeneity of Treponema denticola. J. Periodontal. Res. 20: 602-612.
6. Chu, L., W. Kennell, and S. C. Holt. 1994. Characterization of hemolysis and hemoxidation activities by Treponema denticola. Microb. Pathog. 16:183-195.
7. Chu, L., M. Song, and S. C. Holt. 1994. Effect of iron regulation on expression and hemin binding function of outer-sheath proteins from Treponema denticola. Microb. Pathog. 16:321-335.
8. Chu, L., J. L. Ebersole, G. Kurzban, and S. C. Holt. 1997. Cystalysin, a 46-kilodalton cysteine desulfhydrase from Treponema denticola, with hemolytic and hemoxidative activities. Infect. Immun. 65:3231-3238.
9. Chu, L., J. L. Ebersole, G. P. Kurzban, and S. C. Holt. 1999. Cystalysin, a 46 kDa L-cysteine desulfhydrase from Treponema denticola: biochemical and biophysical characterization. Clin. Infect. Dis. 28:442-450.
10. Cockayne, A., R. Sanger, A. Ivic, R. A. Strugnell, J. H. Macdougall, R. R. B. Russell, and C. W. Penn. 1989. Antigenic and structural analysis of Treponema denticola. J. Gen. Microbiol. 135:3209-3218.
11. Cutler, C. W., P. I. Eke, C. A. Genco, T. E. Van Dyke, and R. R. Arnold. 1996. Hemin-induced modifications of the antigenicity and hemin-binding capacity of Porphyromonas gingivalis lipopolysaccharide. Infect. Immun. 64:2282-2287.
12. D'Alessandro, G., and C. del Carpio. 1958. A lipopolysaccharide antigen of the treponema. Nature (London) 181:991-992.
13. DiRita, V. J., and J. Mekalanos. 1989. Genetic regulation of bacterial virulence. Annu. Rev. Genet. 23:455-482.
14. Ebersole, J. L., L. Kesavalu, S. L. Schneider, R. L. Machen, and S. C. Holt. 1995. Comparative virulence of periodontopathogens in a mouse abscess model. Oral. Dis. 1:115-128.
15. Finlay, B. B., and S. Falkow. 1989. Common themes in microbial pathogenicity. Microbiol. Rev. 53:210-230.
16. Ford, C. W., J. C. Hamel, D. Stapert, and R. J. Yancey. 1989. Establishment of an experimental model of a Staphlococcus aureus abscess in mice by use of dextran and gelatin microcarriers. J. Med. Microbiol. 28:259-266.
17. Galanos, C., M. A. Freudenberg, and W. Feutter. 1979. Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc. Natl. Acad. Sci. USA 76:5939-5943.
18. Genco, C. A., B. M. Odusanya, and G. Brown. 1994. Binding and accumulation of hemin in Porphyromonas gingivalis are induced by hemin. Infect. Immun. 62:2885-2892.
19. Haffajee, A. D., and S. S. Socransky. 1994. Microbial etiological agents of destructive periodontal diseases. Periodontol. 2000 5:78-111.
20. Heithoff, D. M., C. P. Conner, P. C. Hanna, S. M. Julio, U. Hentschel, and M. J. Mahan. 1997. Bacterial infection as assessed by in vivo gene expression. Proc. Natl. Acad. Sci. USA 94:934-939.
21. Helms, S. D., J. D. Oliver, and J. C. Travis. 1984. Role of heme compounds and haptoglobin in Vibrio vulnificus pathogenicity. Infect. Immun. 45:345-349.
22. Kesavalu, L., J. L. Ebersole, and S. C. Holt 1996. Hemin as a modulator of Porphyromonas gingivalis virulence in a murine model. J. Dent. Res. 75:205. (Abstr. 1483.)
23. Kesavalu, L., J. L. Ebersole, R. L. Machen, and S. C. Holt. 1992. Porphyromonas gingivalis virulence in mice: induction of immunity to bacterial components. Infect. Immun. 60:1455-1464.
24. Kesavalu, L., S. C. Holt, R. R. Crawley, R. Borinski, and J. L. Ebersole. 1991. Virulence of Wotinella recta in a murine abscess model. Infect. Immun. 59:2806-2817.
25. Kesavalu, L., S. C. Holt, and J. L. Ebersole. 1996. Trypsin-like protease activity of Porphyromonas gingivalis as a potential virulence factor in a murine lesion model. Microb. Pathog. 20:1-10.
26. Kesavalu, L., S. Walker, S. C. Holt, R. R. Crawley, and J. L. Ebersole. 1997. Virulence characteristics of oral treponemes in a murine model. Infect. Immun. 65:5096-5102.
27. Kim, S. J., L. Chu, and S. C. Holt. 1996. Isolation and characterization of a hemin-binding cell envelope protein from Porphyromonas gingivalis. Microb. Pathog. 21:65-70.
28. Kochan, I., J. T. Kvach, and T. I. Wiles. 1977. Virulence-associated acquisition of iron in mammalian serum by Escherichia coli. J. Infect. Dis. 135: 623-632.
29. Kurimoto, T., M. Suzuki, and T. Watanabe. 1990. Chemical composition and biological activities of lipopolysaccharides extracted from Treponema denticola and Treponema vincentii. Odontology (Tokyo) 78:208-232.
30. Lee, S.-W., J. D. Hillman, and A. Progulske-Fox. 1996. The hemagglutinin genes hagB and hagC of Porphyromonas gingivalis are transcribed in vivo as shown by use of a new expression vector. Infect. Immun. 64:4802-4810.
31. Marsh, P. D., A. S. McDermid, A. S. McKee, and A. Baskerville. 1994. The effect of growth rate and hemin on the virulence and proteolytic activity of Porphyromonas gingivalis W50. Microbiology 140:861-865.
32. Maurelli, A. T. 1989. Temperature regulation of virulence genes in pathogenie bacteria: a general strategy for human pathogens. Microb. Pathog. 7:1-10.
33. McKee, A. S., A. S. McDermid, A. Baskerville, A. B. Dowsett, D. C. Ellwood, and P. D. Marsh. 1986. Effect of hemin on the physiology and virulence of Bacteroides gingivalis W50. Infect. Immun. 52:349-355.
34. Mekalanos, J. J. 1992. Environmental signals controlling expression of virulence determinants in bacteria. J. Bacteriol. 174:1-7.
35. Melton, A. R., and A. A. Weiss. 1989. Environmental regulation of expression of virulence determinants in Bordetella pertussis. J. Bacteriol. 171:6206-6212.
36. Miller, J. F., J. J. Mekalanos, and S. Falkow. 1989. Coordinate regulation and sensory transduction in the control of bacterial virulence. Science 243: 916-922.
37. Moore, W. E. C., and L. V. H. Moore. 1994. The bacteria of periodontal diseases. Periodontol. 2000 5:66-77.
38. Nitta, H., C. Shipley, S. C. Holt, and J. L. Ebersole. Environmental stress effects and S-layer expression by Campylobacter reclus. Submitted for publication.
39. Nuessen, M. E., J. R. Birmingham, and L. A. Joens. 1982. Biological activity of a lipopolysaccharide extracted from Treponema hyodysenteriae. Infect. Immun. 37:138-142.
40. Nuessen, M. E., L. A. Joens, and R. D. Glock. 1983. Involvement of lipopolysaccharide in the pathogenicity of Treponema hyodysenteriae. J. Immunol. 131:997-999.
41. Robins-Browne, R. M., and J. K. Prpic. 1985. Effects of iron and desferri-oxamine on infections with Yersinia enterocolitica. Infect. Immun. 47:774-779.
42. Robins-Browne, R. M., S. Cianciosi, A.-M. Bordun, and G. Wauters. 1991. Pathogenicity of Yersinia kristensenii for mice. Infect. Immun. 59:162-167.
43. Sela, M. N., A. Weinberg, R. Borinsky, S. C. Holt, and T. Dishon. 1988. Inhibition of superoxide production in human polymorphonuclear leukocytes by oral factors. Infect. Immun. 56:589-594.
44. Simonson, L. G., C. H. Goodman, J. J. Bial, and H. E. Morton. 1988. Quantitative relationship of Treponema denticola to severity of periodontal disease. Infect. Immun. 56:726-728.
45. Slauch, J. M., M. J. Mahan, and J. J. Mekalanos. 1994. In vivo expression technology for selection of bacterial genes specifically induced in host tissues. Methods. Enzymol. 235:481-492.
46. Smibert, R. M., and J. A. Burmeister. 1983. Treponema pectinovorum sp. nov. isolated from humans with periodontitis. Int. J. Syst. Bacteriol. 33:852-856.
47. Takayama, K., N. Qureshi, E. Ribi, and J. L. Cantrell. 1984. Separation and characterization of toxic and nontoxic forms of lipid A. Rev. Infect. Dis. 6:439-443.
48. Waalwijk, A., D. M. MacLaren, and J. De Graaff. 1983. In vivo function of hemolysin in the nephropathogenicity of Escherichia coli. Infect. Immun. 42:245-249.
49. Walker, S. G., J. L. Ebersole, and S. C. Holt. 1997. Identification, isolation, and characterization of the 42-kilodalton major outer membrane protein (MompA) from Treponema pectinovorum ATCC 33768. J. Bacteriol. 179: 6441-6447.
50. Weber, F. H., and E. Canale-Parola. 1984. Pectinolytic enzymes of oral spirochetes from humans. Appl. Environ. Microbiol. 48:61-67.
51. Wooldridge, K. G., and P. H. Williams. 1993. Iron uptake mechanisms of pathogenic bacteria. FEMS. Microbiol. Rev. 12:325-348.
52. Wright, A. C., L. M. Simpson, and J. D. Oliver. 1981. Role of iron in the pathogenesis of Vibrio vulnificus infections. Infect. Immun. 34:503-507.
53. Yotis, W. W., V. K. Sharma, C. Gopalsami, S. Chegini, J. McNulty, K. Hoerman, J. Keene, Jr., and L. G. Simonson. 1991. Biochemical properties of the outer membrane of Treponema denticola. J. Clin. Microbiol. 29:1397-1406.
54. Yotis, W. W., F. Macaluso, and C. Gopalsami. 1995. Immunochemical features of a macromolecule of Treponema denticola. J. Basic Microbiol. 35: 255-268.