In situ mRNA hybridization study of the distribution of choline acetyltransferase in the human brain

Brain Research

Volumn 806, Issue 1, 1998, Pages 8-15

  Kasashima, Satomi ^a   Muroishi, Youko ^a   Futakuchi, Hiroko ^a   Nakanishi, Isao ^a   Oda, Yoshio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Brain; Choline acetyltransferase; Human; In situ hybridization

Indexed keywords

CHOLINE ACETYLTRANSFERASE; MESSENGER RNA;

ADULT; AGED; ARTICLE; BASAL GANGLION; BRAIN; BRAIN CORTEX; CEREBELLUM; CHOLINERGIC NERVE CELL; CLINICAL ARTICLE; DIENCEPHALON; ENTORHINAL CORTEX; ENZYME LOCALIZATION; FOREBRAIN; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; ISOTOPE LABELING; MALE; MESENCEPHALON; PONS; PRIORITY JOURNAL; RNA PROBE; TISSUE DISTRIBUTION;

ADULT; AGED; BRAIN; CHOLINE O-ACETYLTRANSFERASE; HUMANS; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; NEURONS; RNA, MESSENGER; TISSUE DISTRIBUTION;

EID: 0032556062     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00677-5     Document Type: Article

References (34)

1. Armstrong D.M., Saper C.B., Levey A.I., Wainer B.H., Terry R.D. Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase. J. Comp. Neurol. 216:1983;53-68.
2. Avendaño C., Umbriaco D., Dykes R.W., Descarries L. Acetylcholine innervation of sensory and motor neocortical areas in adult cat: a choline acetyltransferase immunohistochemical study. J. Chem. Neuroanat. 11:1996;113-130.
3. Butcher L.L., Oh J.D., Woolf N.J., Edwards R.H., Roghani A. Organization of central cholinergic neurons revealed by combined in situ hybridization histochemistry and choline-o-acetyltransferase immunocytochemistry. Neurochem. Int. 21:1992;429-445.
4. Cavicchioli L., Flanigan T.P., Dickson J.G., Vantini G., Dal Toso R., Fusco M., Walsh F.S., Leon A. Choline acetyltransferase messenger RNA expression in developing and adult rat brain: regulation by nerve growth factor. Mol. Brain Res. 9:1991;319-325.
5. Cossette P., Umbriaco D., Zamar N., Hamel E., Descarries L. Recovery of choline acetyltransferase activity without sprouting of the residual acetylcholine innervation in adult rat cerebral cortex after lesion of the nucleus basalis. Brain. Res. 630:1993;195-206.
6. Eckenstein F., Baughman R.W. Two types of cholinergic innervation in cortex, one co-localized with vasoactive intestinal polypeptide. Nature. 309:1984;153-155.
7. Eckenstein F.P., Baughman R.W., Quinn J. An anatomical study of cholinergic innervation in rat cerebral cortex. Neuroscience. 25:1988;457-474.
8. Hedreen J.C., Bacon S.J., Cork L.C., Kitt C.A., Crawford G.D., Salvaterra P.M., Price D.L. Immunocytochemical identification of cholinergic neurons in the monkey nervous system using monoclonal antibodies against choline acetyltransferase. Neurosci. Lett. 43:1983;173-177.
9. Hendry S.H.C., Jones E.G., Killackey H.P., Chalupa L.M. Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex. Dev. Brain Res. 37:1987;313-317.
10. Houser C.R., Crawford G.D., Barber R.P., Salvaterra P.M., Vaughn J.E. Organization and morphological characteristics of cholinergic neurons: an immunocytochemical study with a monoclonal antibody to choline acetyltransferase. Brain Res. 266:1983;97-119.
11. Houser C.R., Crawford G.D., Salvaterra P.M., Vaughn J.E. Immunocytochemical localization of choline acetyltransferase in rat cerebral cortex: a study of cholinergic neurons and synapses. J. Comp. Neurol. 234:1985;17-34.
12. Ibáñez C.F., Ernfors P., Persson H. Developmental and regional expression of choline acetyltransferase mRNA in the rat central nervous system. J. Neurosci. Res. 29:1991;163-171.
13. Ichikawa T., Ajiki K., Matsuura J., Misawa H. Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: in situ hybridization histochemistry and immunohistochemistry. J. Chem. Neuroanat. 13:1997;23-39.
14. Ichikawa T., Hirata Y. Organization of choline acetyltransferase-containing structures in the forebrain of the rat. J. Neurosci. 6:1986;281-292.
15. Kimura H., McGeer P.L., Peng F., McGeer E.G. Choline acetyltransferase-containing neurons in rodent brain demonstrated by immunohistochemistry. Science. 208:1980;1057-1059.
16. Kosaka T., Tauchi M., Dahl J.L. Cholinergic neurons containing GABA-like and/or glutamic acid decarboxylase-like immunoreactivities in various brain regions of the rat. Exp. Brain Res. 70:1988;605-617.
17. Lauterborn J.C., Isackson P.J., Montalvo R., Gall C.M. In situ hybridization localization of choline acetyltransferase mRNA in adult rat brain and spinal cord. Mol. Brain Res. 17:1993;59-69.
18. Levey A.I., Wainer B.H., Rye D.B., Mufson E.J., Mesulam M.-M. Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons. Neuroscience. 13:1984;341-353.
19. Mesulam M.-M., Geula C. Nucleus basalis (Ch4) and cortical cholinergic innervation in the human brain: observation based on the distribution of actylcholinesterase and choline acetyltransferase. J. Comp. Neurol. 275:1988;216-240.
20. Mesulam M.-M., Geula C., Bothwell M.A., Hersh L.B. Human reticular formation: cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei and some cytochemical comparisons to forebrain cholinergic neurons. J. Comp. Neurol. 281:1989;611-633.
21. Mesulam M.-M., Geula C., Cosgrove R., Mash D., Brimijoin S. Immunocytochemical demonstration of axonal and perikaryal acetylcholinesterase in human cerebral cortex. Brain Res. 539:1991;233-238.
22. Mesulam M.-M., Mash D., Hersh L.B., Bothwell M., Geula C. Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus. J. Comp. Neurol. 323:1992;252-268.
23. Mesulam M.-M., Mufson E.J., Lovey A.I., Wainer B.H. Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the sepal area, diagonal band nuclei, nucleus basalis (substantial innominata), and hypothalamus in the rhesus monkey. J. Comp. Neurol. 214:1983;170-197.
24. Mizukawa K., McGeer P.L., Tago H., Peng J.H., McGeer E.G., Kimura H. The cholinergic system of the human hindbrain studied by choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Brain Res. 379:1986;39-55.
25. Mufson E.J., Bothwell M., Hersh L.B., Kordower J.H. Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons. J. Comp. Neurol. 285:1989;196-217.
26. Oda Y., Nakanishi I., Deguchi T. A complementary DNA for human choline acetyltransferase induces two forms of enzyme with different molecular weights in cultured cells. Mol. Brain Res. 16:1992;287-294.
27. Oda Y., Imai S., Nakanishi I., Ichikawa T., Deguchi T. Immunohistochemical study on choline acetyltransferase in the spinal cord of patients with amyotrophic lateral sclerosis. Pathol. Int. 45:1995;933-939.
28. Oda Y., Yamashita N., Muroishi Y., Nakanishi I. Localization of choline acetyltransferase and acetylcholine in the chorion of early human pregnancy. Histochem. Cell Biol. 105:1996;93-99.
29. Oh J.D., Woolf N.J., Roghani A., Edwards R.H., Butcher L.L. Cholinergic neurons in the rat central nervous system demonstrated by in situ hybridization of choline acetyltransferase mRNA. Neuroscience. 47:1992;807-822.
30. Stichel C.C., Dolabela de Lima A., Singer W. A search for choline acetyltransferase-like immunoreactivity in neurons of cat striate cortex. Brain Res. 405:1987;395-399.
31. Strada O., Vyas S., Hirsch E.C., Ruberg M., Brice A., Agid Y., Javoy-Agid F. Decreased choline acetyltransferase mRNA expression in the nucleus basalis of Mynert in Alzheimer disease: an in situ hybridization study. Proc. Natl. Acad. Sci. USA. 89:1992;9549-9553.
32. Umbriaco D., Watkins K.C., Descarries L., Cozzari C., Hartman B.K. Ultrastructural and morphometric features of the acetylcholine innervation in adult rat parietal cortex: an electron microscopic study in serial sections. J. Comp. Neurol. 348:1994;351-373.
33. Virgo L., de Belleroche J., Rossi M., Steiner T.J. Characterisation of the distribution of choline actyltransferase messenger RNA in the human spinal cord and its depletion in motor neuron disease. J. Neurol. Sci. 112:1992;126-132.
34. Woolf N.J. Cholinergic systems in mammalian brain and spinal cord. Prog. Neurobiol. 37:1991;475-524.