메뉴 건너뛰기




Volumn 79, Issue 7-8, 1999, Pages 1190-1198

Prognostic impact of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) in cytosols and pellet extracts derived from 892 breast cancer patients

Author keywords

Breast cancer; Cytosol; Enzyme linked immunosorbent assay; Plasminogen activator inhibitor; Prognostic impact; Urokinase type plasminogen activator

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1; UROKINASE;

EID: 0033016406     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690191     Document Type: Article
Times cited : (38)

References (29)
  • 2
    • 0030788411 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator system in cancer metastasis: A review
    • Andreasen PA, Kjoller L, Christensen L and Duffy MJ (1997) The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 72: 1-22
    • (1997) Int J Cancer , vol.72 , pp. 1-22
    • Andreasen, P.A.1    Kjoller, L.2    Christensen, L.3    Duffy, M.J.4
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Annal Biochem 72: 248-254
    • (1976) Annal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0030842795 scopus 로고    scopus 로고
    • Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration
    • Chapman HA (1997) Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration. Curr Opin Cell Biol 9: 714-724
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 714-724
    • Chapman, H.A.1
  • 8
    • 0027994264 scopus 로고
    • The urokinase receptor: Protein structure and role in plasminogen activation and cancer invasion
    • Danø K, Behrendt N, Brünner N, Ellis V, Ploug M and Pyke C (1994) The urokinase receptor: protein structure and role in plasminogen activation and cancer invasion. Fibrinolysis 8(suppl. 1): 189-203
    • (1994) Fibrinolysis , vol.8 , Issue.SUPPL. 1 , pp. 189-203
    • Danø, K.1    Behrendt, N.2    Brünner, N.3    Ellis, V.4    Ploug, M.5    Pyke, C.6
  • 9
    • 0026522287 scopus 로고
    • The role of proteolytic enzymes in cancer invasion and metastasis
    • Duffy MJ (1992) The role of proteolytic enzymes in cancer invasion and metastasis. Clin Exp Metastasis 10: 145-155
    • (1992) Clin Exp Metastasis , vol.10 , pp. 145-155
    • Duffy, M.J.1
  • 10
    • 0030002073 scopus 로고    scopus 로고
    • Proteases as prognostic markers in cancer
    • Duffy MJ (1996) Proteases as prognostic markers in cancer. Clin Cancer Res 2: 613-618
    • (1996) Clin Cancer Res , vol.2 , pp. 613-618
    • Duffy, M.J.1
  • 12
    • 0019083094 scopus 로고
    • Revision of the standards for the assessment of hormone receptors in human breast cancer; report of the second EORTC workshop, held on 16-17 March 1979, in The Netherlands Cancer Institute
    • EORTC Breast Cancer Cooperative Group (1980) Revision of the standards for the assessment of hormone receptors in human breast cancer; report of the second EORTC workshop, held on 16-17 March 1979, in The Netherlands Cancer Institute. Eur J Cancer 16: 1513-1515
    • (1980) Eur J Cancer , vol.16 , pp. 1513-1515
  • 13
    • 0029950191 scopus 로고    scopus 로고
    • Urokinase plasminogen activator, a strong independent prognostic-factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay
    • Fernö M, Bendahl P-O, Borg Å, Brundell J, Hirschberg L, Olsson H and Killander D (1996) Urokinase plasminogen activator, a strong independent prognostic-factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay. Eur J Cancer 32A: 793-801
    • (1996) Eur J Cancer , vol.32 A , pp. 793-801
    • Fernö, M.1    Bendahl, P.-O.2    Borg, Å.3    Brundell, J.4    Hirschberg, L.5    Olsson, H.6    Killander, D.7
  • 17
    • 0030916215 scopus 로고    scopus 로고
    • A sensitive and robust assay for urokinase and tissue-type plasminogen activators (uPA and tPA) and their inhibitor type I (PAI-1 ) in breast tumor cytosols
    • Grebenschikov N. Geurts-Moespot A, De Witte H, Heuvel J, Leake R, Sweep F and Benraad T (1997) A sensitive and robust assay for urokinase and tissue-type plasminogen activators (uPA and tPA) and their inhibitor type I (PAI-1 ) in breast tumor cytosols. Int J Biol Markers 12: 6-14
    • (1997) Int J Biol Markers , vol.12 , pp. 6-14
    • Grebenschikov, N.1    Geurts-Moespot, A.2    De Witte, H.3    Heuvel, J.4    Leake, R.5    Sweep, F.6    Benraad, T.7
  • 18
    • 0027223048 scopus 로고
    • High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis
    • Grøndahl-Hansen J, Christensen IJ, Rosenquist C, Brünner N, Mouridsen HT, Danø K and Blichert-Toft M (1993) High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis. Cancer Res 53: 2513-2521
    • (1993) Cancer Res , vol.53 , pp. 2513-2521
    • Grøndahl-Hansen, J.1    Christensen, I.J.2    Rosenquist, C.3    Brünner, N.4    Mouridsen, H.T.5    Danø, K.6    Blichert-Toft, M.7
  • 19
    • 0024428950 scopus 로고
    • Urokinase-type plasminogen activator antigen and early relapse in breast cancer
    • Jänicke F, Schmitt M, Ulm K, Gössner W and Graeff H (1989) Urokinase-type plasminogen activator antigen and early relapse in breast cancer. Lancet 8670: 1049
    • (1989) Lancet , vol.8670 , pp. 1049
    • Jänicke, F.1    Schmitt, M.2    Ulm, K.3    Gössner, W.4    Graeff, H.5
  • 21
    • 0025995880 scopus 로고
    • Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type-1 inhibitor in breast cancer
    • Jänicke F, Schmitt M and Graeff H (1991) Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type-1 inhibitor in breast cancer. Semin Thromb Hemostas 17: 303-312
    • (1991) Semin Thromb Hemostas , vol.17 , pp. 303-312
    • Jänicke, F.1    Schmitt, M.2    Graeff, H.3
  • 22
    • 0027082979 scopus 로고
    • Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer
    • Jänicke F, Schmitt M, Pache L, Ulm K, Harbeck N, Höfler H and Graeff H (1993) Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer. Breast Cancer Res Treat 24: 195-208
    • (1993) Breast Cancer Res Treat , vol.24 , pp. 195-208
    • Jänicke, F.1    Schmitt, M.2    Pache, L.3    Ulm, K.4    Harbeck, N.5    Höfler, H.6    Graeff, H.7
  • 23
    • 0028358771 scopus 로고
    • Both the cytosols and detergent extracts of breast cancer tissues are suited to evaluate the prognostic impact of the urokinase-type plasminogen activator and its inhibitor, plasminogen activator inhibitor type 1
    • Jänicke F, Pache L, Schmitt M, Ulm K, Thomssen C, Prechtl A and Graeff H (1994a) Both the cytosols and detergent extracts of breast cancer tissues are suited to evaluate the prognostic impact of the urokinase-type plasminogen activator and its inhibitor, plasminogen activator inhibitor type 1. Cancer Res 54: 2527-2530
    • (1994) Cancer Res , vol.54 , pp. 2527-2530
    • Jänicke, F.1    Pache, L.2    Schmitt, M.3    Ulm, K.4    Thomssen, C.5    Prechtl, A.6    Graeff, H.7
  • 24
    • 0002961213 scopus 로고
    • Urokinase (uPA) and PAI-1 as selection criteria for adjuvant chemotherapy in axillary node-negative breast cancer patients
    • Schmitt M, Graeff H and Kindermann G (eds). Elsevier Publishers: Amsterdam
    • Jänicke F, Thomssen C, Pache L, Schmitt M and Graeff H (1994b) Urokinase (uPA) and PAI-1 as selection criteria for adjuvant chemotherapy in axillary node-negative breast cancer patients. In Prospects in Diagnosis and Treatment of Breast Cancer, Schmitt M, Graeff H and Kindermann G (eds), pp. 207-218. Elsevier Publishers: Amsterdam
    • (1994) Prospects in Diagnosis and Treatment of Breast Cancer , pp. 207-218
    • Jänicke, F.1    Thomssen, C.2    Pache, L.3    Schmitt, M.4    Graeff, H.5
  • 25
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observation
    • Kaplan EL and Meier P (1958) Nonparametric estimation from incomplete observation. J Am Stat Assoc 53: 457-181
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-1181
    • Kaplan, E.L.1    Meier, P.2
  • 26
    • 0020358908 scopus 로고
    • Role of collagenases in tumor cell invasion, tissue degradation, and cancer
    • Liotta LA, Thorgeirsson UP and Garbisa S (1982) Role of collagenases in tumor cell invasion, tissue degradation, and cancer. Cancer Metastasis Rev 1: 277-297
    • (1982) Cancer Metastasis Rev , vol.1 , pp. 277-297
    • Liotta, L.A.1    Thorgeirsson, U.P.2    Garbisa, S.3
  • 27
    • 0027535914 scopus 로고
    • Biology and biochemistry of proteinases in tumor invasion
    • Mignatli P and Rifkin DB (1993) Biology and biochemistry of proteinases in tumor invasion. Physiol Rev 73: 161-195
    • (1993) Physiol Rev , vol.73 , pp. 161-195
    • Mignatli, P.1    Rifkin, D.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.