메뉴 건너뛰기




Volumn 27, Issue 2, 1997, Pages 121-127

Defects of β2-adrenergic signal transduction in chronic lymphocytic leukaemia: Relationship to disease progression

Author keywords

adenylyl cyclase; adrenergic receptor; chronic lymphocytic leukaemia; forskolin; isoprenaline

Indexed keywords

ADENYLATE CYCLASE; BETA 2 ADRENERGIC RECEPTOR; CHOLERA TOXIN; CYANOPINDOLOL I 125; CYCLIC AMP; FORSKOLIN; ISOPRENALINE;

EID: 0031046827     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.1997.700623.x     Document Type: Article
Times cited : (14)

References (45)
  • 1
    • 0021272384 scopus 로고
    • Proteins and dual control ot the adenylate cyclase
    • Gilman AG. Proteins and dual control ot the adenylate cyclase. Cell 1984;36:577-9.
    • (1984) Cell , vol.36 , pp. 577-579
    • Gilman, A.G.1
  • 2
    • 0019799997 scopus 로고
    • The β-adrenergic receptor in human lymphocytes: Subclassification by the use of a new radioligand (±)-[125]Iodocyanopindolol
    • Brodde OE, Engel G, Hoyer D, Bock KD, Weber F. The β-adrenergic receptor in human lymphocytes: subclassification by the use of a new radioligand (±)-[125]Iodocyanopindolol. Life Sci 1981;29:2189-98.
    • (1981) Life Sci , vol.29 , pp. 2189-2198
    • Brodde, O.E.1    Engel, G.2    Hoyer, D.3    Bock, K.D.4    Weber, F.5
  • 3
    • 0026785920 scopus 로고
    • Adenylyl cyclases
    • Tang WJ, Gilman AG. Adenylyl cyclases. Cell 1992;70:869-72.
    • (1992) Cell , vol.70 , pp. 869-872
    • Tang, W.J.1    Gilman, A.G.2
  • 4
    • 0020357890 scopus 로고
    • Priming of human myeloid leukemic cell lines HL-60 and U-937 with retinoic acid for differentiation effects of cyclic 3′:5′-adenosine monophospate-inducing agents and a T-lymphocyte differentiation factor
    • Olsson IL, Breitmann TR, Gallo RC, Priming of human myeloid leukemic cell lines HL-60 and U-937 with retinoic acid for differentiation effects of cyclic 3′:5′-adenosine monophospate-inducing agents and a T-lymphocyte differentiation factor. Cancer Res 1982;42:3928-33.
    • (1982) Cancer Res , vol.42 , pp. 3928-3933
    • Olsson, I.L.1    Breitmann, T.R.2    Gallo, R.C.3
  • 5
    • 0015010757 scopus 로고
    • Stimulation by epinephrine of adenyl cyclase activity, cyclic AMP formation, DNA synthesis and cell proliferation in populations of rat thymocytic lymphocytes
    • MacManus JP, Whitfield JH, Youdale T. Stimulation by epinephrine of adenyl cyclase activity, cyclic AMP formation, DNA synthesis and cell proliferation in populations of rat thymocytic lymphocytes. J Biol Cell Phys 1970;77:103-16.
    • (1970) J Biol Cell Phys , vol.77 , pp. 103-116
    • MacManus, J.P.1    Whitfield, J.H.2    Youdale, T.3
  • 6
    • 0016638516 scopus 로고
    • The modulation of spontaneous and anti Ig stimulated motility of lymphocytes by cyclic nucleotides and adrenergic and cholinergic agents
    • Schreiner GF, Unanaue ER. The modulation of spontaneous and anti Ig stimulated motility of lymphocytes by cyclic nucleotides and adrenergic and cholinergic agents. J Immunol 1975;114:802-5.
    • (1975) J Immunol , vol.114 , pp. 802-805
    • Schreiner, G.F.1    Unanaue, E.R.2
  • 7
    • 84907105215 scopus 로고
    • Adenyl cyclase-stimulating catecholamines as modifiers of antibody formation
    • Braun W, Rega MJ. Adenyl cyclase-stimulating catecholamines as modifiers of antibody formation. Immunol Commun 1972; 1:523-32.
    • (1972) Immunol Commun , vol.1 , pp. 523-532
    • Braun, W.1    Rega, M.J.2
  • 8
    • 0016427434 scopus 로고
    • The influence of intracellular levels of cyclic nucleotides on cell proliferation and the induction of antibody synthesis
    • Watson J. The influence of intracellular levels of cyclic nucleotides on cell proliferation and the induction of antibody synthesis. J Exp Med 1975;141:97-111.
    • (1975) J Exp Med , vol.141 , pp. 97-111
    • Watson, J.1
  • 9
    • 0021954564 scopus 로고
    • Neurotransmitters, hormones, and cyclic nucleotides in lymphocyte regulation
    • Coffey RG, Hadden JW. Neurotransmitters, hormones, and cyclic nucleotides in lymphocyte regulation. Fed Proc 1985;44:112-7.
    • (1985) Fed Proc , vol.44 , pp. 112-117
    • Coffey, R.G.1    Hadden, J.W.2
  • 10
    • 0026528602 scopus 로고
    • G protein-controlled signal transduction pathways and the regulation of cell proliferation
    • Seuwen K, Pouysssegur J. G protein-controlled signal transduction pathways and the regulation of cell proliferation. Adv Cancer Res 1992;58:75-94.
    • (1992) Adv Cancer Res , vol.58 , pp. 75-94
    • Seuwen, K.1    Pouysssegur, J.2
  • 11
    • 0021740024 scopus 로고
    • Plasma and urine cyclic nucleotide levels in patients with neoplastic diseases
    • Perrachi M, Lombardi L, Toschi V et al. Plasma and urine cyclic nucleotide levels in patients with neoplastic diseases. Cancer 1984;54:3028.
    • (1984) Cancer , vol.54 , pp. 3028
    • Perrachi, M.1    Lombardi, L.2    Toschi, V.3
  • 12
    • 0018745724 scopus 로고
    • Cyclic AMP in human lymphocytes. Levels in akute leukemia and infectious mononucleosis
    • Ben-Zvi A, Russel A, Sheneyour A, Trainin N. Cyclic AMP in human lymphocytes. Levels in akute leukemia and infectious mononucleosis. Eur J Cancer 1979;15:615-7.
    • (1979) Eur J Cancer , vol.15 , pp. 615-617
    • Ben-Zvi, A.1    Russel, A.2    Sheneyour, A.3    Trainin, N.4
  • 13
    • 0016702719 scopus 로고
    • Cyclic adenosine 3′:5′-monophosphate levels and activities of related enzymes in normal and leukemic lymphocytes
    • Monahan TM, Marchand NW, Fritz RR, Abell CW. Cyclic adenosine 3′:5′-monophosphate levels and activities of related enzymes in normal and leukemic lymphocytes. Cancer Res 1975;35:2540-7.
    • (1975) Cancer Res , vol.35 , pp. 2540-2547
    • Monahan, T.M.1    Marchand, N.W.2    Fritz, R.R.3    Abell, C.W.4
  • 14
    • 0025786867 scopus 로고
    • Reduced responsiveness of adenylate cyclase to forskolin in human lymphoma cells
    • Hallek M, Kamp T, Haen E, Göhly U, Emmerich B, Remien J. Reduced responsiveness of adenylate cyclase to forskolin in human lymphoma cells. Biochem Pharmacol 1991;42:1329-34.
    • (1991) Biochem Pharmacol , vol.42 , pp. 1329-1334
    • Hallek, M.1    Kamp, T.2    Haen, E.3    Göhly, U.4    Emmerich, B.5    Remien, J.6
  • 15
    • 0019782806 scopus 로고
    • Lymphocytes aminergic binding in chronic lymphocytic leukemia
    • Bidart JM, Motte P, Bohoun C, Bellet D. Lymphocytes aminergic binding in chronic lymphocytic leukemia. Leukemia Res 1981; 5(6):443-6.
    • (1981) Leukemia Res , vol.5 , Issue.6 , pp. 443-446
    • Bidart, J.M.1    Motte, P.2    Bohoun, C.3    Bellet, D.4
  • 16
    • 0017739663 scopus 로고
    • Catecholamine hormone receptors are reduced on chronic lymphocytic leukemic lymphocytes
    • Sheppard JR, Gormus R, Moldow CF. Catecholamine hormone receptors are reduced on chronic lymphocytic leukemic lymphocytes. Nature 1977;269:693-5.
    • (1977) Nature , vol.269 , pp. 693-695
    • Sheppard, J.R.1    Gormus, R.2    Moldow, C.F.3
  • 17
    • 0020629672 scopus 로고
    • Differences in β-adrenergic receptor density and adenylate cyclase activity between normal and leukemic lymphocytes
    • Paietta E, Schwarzmeier JD. Differences in β-adrenergic receptor density and adenylate cyclase activity between normal and leukemic lymphocytes. Eur J Clin Invest 1983;13:339-46.
    • (1983) Eur J Clin Invest , vol.13 , pp. 339-346
    • Paietta, E.1    Schwarzmeier, J.D.2
  • 18
    • 8044250316 scopus 로고
    • Revised radioreceptor assay for β-adrenoceptors expressed on peripheral mononuclear leukocytes
    • Haen E, Liebl B, Lederer T, Pliska V. Revised radioreceptor assay for β-adrenoceptors expressed on peripheral mononuclear leukocytes. Pharmacol Toxicol 1987;61:265-70.
    • (1987) Pharmacol Toxicol , vol.61 , pp. 265-270
    • Haen, E.1    Liebl, B.2    Lederer, T.3    Pliska, V.4
  • 19
    • 0019518522 scopus 로고
    • Chronic lymphocytic leukemia: Proposal for a revised staging system
    • Binet JL, Catovsky D, Chandra P. Chronic lymphocytic leukemia: proposal for a revised staging system. Br J Haematol 1981;48: 365-7.
    • (1981) Br J Haematol , vol.48 , pp. 365-367
    • Binet, J.L.1    Catovsky, D.2    Chandra, P.3
  • 20
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood
    • Böyum A. Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Invest 1968;21(Suppl. 97):77-89.
    • (1968) Scand J Clin Invest , vol.21 , Issue.97 SUPPL. , pp. 77-89
    • Böyum, A.1
  • 21
    • 0023808918 scopus 로고
    • Circannual variation in the expression of β2-adrenoceptors on human peripheral mononuclear leukocytes
    • Haen E, Langenmayer I, Pangerl A, Liebl B, Remien J. Circannual variation in the expression of β2-adrenoceptors on human peripheral mononuclear leukocytes. Klin Wschr 1988;66:579-82.
    • (1988) Klin Wschr , vol.66 , pp. 579-582
    • Haen, E.1    Langenmayer, I.2    Pangerl, A.3    Liebl, B.4    Remien, J.5
  • 22
    • 0023952217 scopus 로고
    • Kinetic and equilibrium studies of (-)125Iodocyanopindolol binding to β-adrenoceptors on human lymphocytes: Evidence for the existence of two classes of binding sites
    • Anhäupl T, Liebl B, Remien J. Kinetic and equilibrium studies of (-)125Iodocyanopindolol binding to β-adrenoceptors on human lymphocytes: evidence for the existence of two classes of binding sites. J Receptor Res 1988;8(1-4):47-57.
    • (1988) J Receptor Res , vol.8 , Issue.1-4 , pp. 47-57
    • Anhäupl, T.1    Liebl, B.2    Remien, J.3
  • 23
    • 84969001783 scopus 로고
    • The attraction of proteins for small molecules and ions
    • Scatchard G. The attraction of proteins for small molecules and ions. Ann NY Acad Sci 1949;51:660-72.
    • (1949) Ann NY Acad Sci , vol.51 , pp. 660-672
    • Scatchard, G.1
  • 24
    • 0016374975 scopus 로고
    • A highly sensitive adenylate cyclase assay
    • Salomon Y, Londos C, Rodbell M. A highly sensitive adenylate cyclase assay. Anal Biochem 1974;58541-8.
    • (1974) Anal Biochem , pp. 58541-58548
    • Salomon, Y.1    Londos, C.2    Rodbell, M.3
  • 25
    • 0016176358 scopus 로고
    • Adenylate cyclase activity in fibroblasts transformed by Kirsten or Moloney sarcoma viruses
    • Anderson WB, Gallo R, Pastan I. Adenylate cyclase activity in fibroblasts transformed by Kirsten or Moloney sarcoma viruses. J Biol Chem 1974;249:7041-8.
    • (1974) J Biol Chem , vol.249 , pp. 7041-7048
    • Anderson, W.B.1    Gallo, R.2    Pastan, I.3
  • 26
    • 0017102582 scopus 로고
    • Role of cyclic nucleotides in cell growth and differentiation
    • Friedman DL. Role of cyclic nucleotides in cell growth and differentiation. Physiol Rev 1976;56(4):652-708.
    • (1976) Physiol Rev , vol.56 , Issue.4 , pp. 652-708
    • Friedman, D.L.1
  • 27
    • 0015089453 scopus 로고
    • Further changes in differentiation state accompanying the conversion of chinese hamster cells to fibroblastic form by dibutyryl adenosine cyclic 3′:5′-monophosphate and hormones
    • Hsie A, Jones C, Puck T. Further changes in differentiation state accompanying the conversion of chinese hamster cells to fibroblastic form by dibutyryl adenosine cyclic 3′:5′-monophosphate and hormones. Proc Natl Acad Sci USA 1971;68:1648.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 1648
    • Hsie, A.1    Jones, C.2    Puck, T.3
  • 29
    • 0021738482 scopus 로고
    • Beta-adrenergic receptors are different in subpopulations of human circulating lymphocytes
    • Landmann RMA, Bürgisser E, Wesp M, Bühler FR. Beta-adrenergic receptors are different in subpopulations of human circulating lymphocytes. J Receptor Res 1984;4:37-50.
    • (1984) J Receptor Res , vol.4 , pp. 37-50
    • Landmann, R.M.A.1    Bürgisser, E.2    Wesp, M.3    Bühler, F.R.4
  • 30
    • 0025925067 scopus 로고
    • Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation
    • Okamoto T, Murayama Y, Hayashi Y, Inagaki M, Ogata E, Nishimoto I. Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation. Cell 1991;67:723-30.
    • (1991) Cell , vol.67 , pp. 723-730
    • Okamoto, T.1    Murayama, Y.2    Hayashi, Y.3    Inagaki, M.4    Ogata, E.5    Nishimoto, I.6
  • 31
    • 0040472716 scopus 로고
    • Coupling of β-adrenoceptors to adenylate cyclase and the role of the GTP binding protein in signal transduction
    • Little Rock: Alan R. Liss
    • Levitzky A. Coupling of β-adrenoceptors to adenylate cyclase and the role of the GTP binding protein in signal transduction. In: Perspectives on Receptor Classiciation. Little Rock: Alan R. Liss, 1987;87-94.
    • (1987) Perspectives on Receptor Classiciation , pp. 87-94
    • Levitzky, A.1
  • 32
    • 0027712045 scopus 로고
    • Increased expression of Gi alpha 2 in mouse embryo stem cells promotes terminal differentiation to adipocytes
    • Su HL, Malbon CC, Wang HY. Increased expression of Gi alpha 2 in mouse embryo stem cells promotes terminal differentiation to adipocytes. Am J Physiol 1993;265(Pt 1):C1729-35.
    • (1993) Am J Physiol , vol.265 , Issue.1 PART
    • Su, H.L.1    Malbon, C.C.2    Wang, H.Y.3
  • 33
    • 0027194487 scopus 로고
    • G protein-coupled receptor kinases
    • Lefkowitz RJ. G protein-coupled receptor kinases. Cell 1993; 74:409-12.
    • (1993) Cell , vol.74 , pp. 409-412
    • Lefkowitz, R.J.1
  • 34
    • 0026551650 scopus 로고
    • Adrenergic receptors as models for G protein-coupled receptors
    • Kobilka B. Adrenergic receptors as models for G protein-coupled receptors. Ann Rev Neurosci 1992;15:87-114.
    • (1992) Ann Rev Neurosci , vol.15 , pp. 87-114
    • Kobilka, B.1
  • 35
    • 0023626599 scopus 로고
    • Forskolin resistant Y1 mutants harbor defects associated with the guanyl nucleotide-binding regulatory protein, Gs
    • Schimmer BP, Tsao J, Borenstein R, Endrenyi L. Forskolin resistant Y1 mutants harbor defects associated with the guanyl nucleotide-binding regulatory protein, Gs. J Biol Chem 1987;262:15521-6.
    • (1987) J Biol Chem , vol.262 , pp. 15521-15526
    • Schimmer, B.P.1    Tsao, J.2    Borenstein, R.3    Endrenyi, L.4
  • 36
    • 8044249012 scopus 로고
    • GTP-bindende Proteine in der Pathophysiologie innerer Erkrankungen
    • Zeuzem S, Schulz I, Caspary WF. GTP-bindende Proteine in der Pathophysiologie innerer Erkrankungen. Dt Ärztebl 1992;89(33):A 2768-74.
    • (1992) Dt Ärztebl , vol.89 , Issue.33
    • Zeuzem, S.1    Schulz, I.2    Caspary, W.F.3
  • 37
    • 0026657153 scopus 로고
    • Defective guanyl nucleotide binding protein βγ subunits in a forskolin-resistant mutant of the Y1 adrenocortical cell line
    • Mitchell J, Northup JK, Schimmer BP. Defective guanyl nucleotide binding protein βγ subunits in a forskolin-resistant mutant of the Y1 adrenocortical cell line. Proc Natl Acad Sci USA 1992;89: 8933-7.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8933-8937
    • Mitchell, J.1    Northup, J.K.2    Schimmer, B.P.3
  • 38
    • 0008534153 scopus 로고
    • Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells
    • Haga T, Ross EM, Anderson HJ, Gilman AG. Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells. Proc Natl Acad Sci USA 1977; 74:2016-20.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 2016-2020
    • Haga, T.1    Ross, E.M.2    Anderson, H.J.3    Gilman, A.G.4
  • 39
    • 0022448423 scopus 로고
    • β-adrenergic receptor of S49 mouse lymphoma cells: Purification and properties
    • George ST, Malbon CC. β-adrenergic receptor of S49 mouse lymphoma cells: purification and properties. Ann NY Acad Sci 1987;84:99-101.
    • (1987) Ann NY Acad Sci , vol.84 , pp. 99-101
    • George, S.T.1    Malbon, C.C.2
  • 40
    • 0019986148 scopus 로고
    • Three adenylate cyclase phenotypes in S49 lymphoma cells produced by mutations of one gene
    • Bourne HR, Beiderman B, Steinberg F, Brothers VM. Three adenylate cyclase phenotypes in S49 lymphoma cells produced by mutations of one gene. Mol Pharmacol 1982;22:205-10.
    • (1982) Mol Pharmacol , vol.22 , pp. 205-210
    • Bourne, H.R.1    Beiderman, B.2    Steinberg, F.3    Brothers, V.M.4
  • 41
    • 0027770782 scopus 로고
    • Mutations in G protein-linked receptors: Novel insights on disease
    • Clapham DE. Mutations in G protein-linked receptors: novel insights on disease. Cell 1993;75:1237-9.
    • (1993) Cell , vol.75 , pp. 1237-1239
    • Clapham, D.E.1
  • 42
    • 0028281397 scopus 로고
    • Hereditary and acquired defects in signaling through the hormone-receptor-G protein complex
    • Raymond JR. Hereditary and acquired defects in signaling through the hormone-receptor-G protein complex. Am J Physiol 1994; 266:F163-74.
    • (1994) Am J Physiol , vol.266
    • Raymond, J.R.1
  • 43
    • 0027325610 scopus 로고
    • Abnormalities in G protein-coupled signal transduction pathways in human disease
    • Spiegel AM, Weinstein LS, Shenker A. Abnormalities in G protein-coupled signal transduction pathways in human disease. J Clin Invest 1993;92:1119-25.
    • (1993) J Clin Invest , vol.92 , pp. 1119-1125
    • Spiegel, A.M.1    Weinstein, L.S.2    Shenker, A.3
  • 44
    • 0025325342 scopus 로고
    • Cytotoxic effect of TNF-alpha and abnormal regulation of cAMP in the retinoid resistant cell line U937/GTB
    • Botilsrud M, Kvam L, Blomhoff HK, Norum K, Blomhoff R. Cytotoxic effect of TNF-alpha and abnormal regulation of cAMP in the retinoid resistant cell line U937/GTB. Anticancer Res 1990;10:433-6.
    • (1990) Anticancer Res , vol.10 , pp. 433-436
    • Botilsrud, M.1    Kvam, L.2    Blomhoff, H.K.3    Norum, K.4    Blomhoff, R.5
  • 45
    • 0023900983 scopus 로고
    • Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase
    • Inhorn L, Fleming JW, Klingberg D, Gabig T, Boswell HS. Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase. Blood 1988; 71:1003-11.
    • (1988) Blood , vol.71 , pp. 1003-1011
    • Inhorn, L.1    Fleming, J.W.2    Klingberg, D.3    Gabig, T.4    Boswell, H.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.