Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53

Human Genetics

Volumn 104, Issue 1, 1999, Pages 15-22

  Wacey, A I ^a   Cooper, D N ^b   Liney, D ^c   Hovig, E ^d   Krawczak, M ^b  

^a THROMBOSIS RESEARCH INSTITUTE   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 9; DNA BINDING PROTEIN; MUTANT PROTEIN; PROTEIN P53; ZINC ION;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DNA BINDING; GENE MUTATION; HEMOPHILIA B; HUMAN; HYDROGEN BOND; METAL BINDING; MISSENSE MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE;

AMINO ACID SUBSTITUTION; BINDING SITES; HUMANS; HYDROGEN BONDING; PEPTIDE FRAGMENTS; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; SOLVENTS; STEREOISOMERISM; THERMODYNAMICS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0033012815     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390050904     Document Type: Article

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