Somatic mutation analysis of IgH variable regions reveals that tumor cells of most parafollicular (monocytoid) B-cell lymphoma, splenic marginal zone B-cell lymphoma, and some hairy cell leukemia are composed of memory B lymphocytes

Human Pathology

Volumn 30, Issue 3, 1999, Pages 306-312

  Miranda, Roberto N ^a   Cousar, John B ^a   Hammer, Richard D ^a   Collins, Robert D ^a   Vnencak Jones, Cindy L ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

B cell neoplasms; DNA sequencing; Immunoglobulin heavy chain variable region genes; Polymerase chain reaction; Somatic mutations

Indexed keywords

DNA; IMMUNOGLOBULIN HEAVY CHAIN;

ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; B CELL LYMPHOMA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE REARRANGEMENT; GENE SEQUENCE; GERMINAL CENTER; HAIRY CELL LEUKEMIA; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTE CLONE; MALE; MEMORY CELL; MONOCYTE; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; SOMATIC MUTATION;

EID: 0033012752     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(99)90010-2     Document Type: Article

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