Low BCL-2 expression in acute leukemia with t(8;21) chromosomal abnormality

Leukemia

Volumn 13, Issue 3, 1999, Pages 358-368

  Shikami, M ^a   Miwa, H ^a   Nishii, K ^a   Takahashi, T ^a   Sekine, T ^a   Mahmud, N ^a   Nishikawa, M ^a   Shiku, H ^a   Kamada, N ^b   Kita, K ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

BCL 2; Cell cycle; t(8; 21)AML

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 5; PROTEIN BCL 2;

ACUTE LEUKEMIA; APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL CYCLE PHASE; CELL DIFFERENTIATION; CELL POPULATION; CHROMOSOME 21; CHROMOSOME 8; CHROMOSOME ABERRATION; CLINICAL TRIAL; COLONY FORMATION; DNA SYNTHESIS; EOSINOPHILIA; GENE TRANSLOCATION; HUMAN; HUMAN CELL; NEUTROPHIL; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0033012230     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401343     Document Type: Article

References (49)

1. Rowley JD. Identification of a translocation with quinacrine fluorescence in a patient with acute leukemia. Ann Genet 1973; 16: 109-112.
2. Kamada N, Okada K, Oguma N, Tanaka R, Mikami M, Uchino H. C-G translocation in acute myelocytic leukemia with low neutrophil alkaline phosphatase activity. Cancer 1976; 37: 2380-2387.
3. Hagemeijer A, Garson OM, Kondo K. Fourth International Workshop on Chromosomes in Leukemia, 1982. Translocation (8;21)(q22;q22) in acute nonlymphocytic leukemia. Cancer Genet Cytogenet 1984; 11: 284-287.
4. Ishibashi T, Kimura H, Abe R, Matsuda S, Uchida T, Kariyone S. Involvement of eosinophils in leukemia: cytogenetic study of eosinophilic colonies from acute myelogenous leukemia associated with translocation (8;21). Cancer Genet Cytogenet 1986; 22: 189-194.
5. Kita K, Nakase K, Miwa H, Masuya M, Nishii K, Morita N, Takakura N, Otsuji A, Shirakawa S, Ueda T, Nasu K, Kyo T, Dohy H, Kamada N. Phenotypical characteristics of acute myeloid leukemia associated with the t(8;21)(q22;q22) chromosomal abnormality: frequent expression of immature B cell antigen CD19 together with stem cell antigen CD34. Blood 1992; 80: 470-477.
6. Mizutani M, Yamaguchi M, Miwa H, Kawamura T, Okuno T, Nishii K, Shiku H, Kamada N, Kita K. Frequent expression of MDR1 and MDR3 genes in acute myelocytic leukemia cells with t(8;21)(q22;q22). Int J Oncol 1997; 10: 473-479.
7. Gao J, Erickson P, Gardiner K, Le Beau MM, Diaz MO, Patterson D, Rowly JD, Drabkin HA. Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21) (q22;q22.3) in acute myelogenous leukemia. Proc Natl Acad Sci USA 1991; 88: 4882-4886.
8. Miyoshi H, Shimizu K, Kozu T, Maseki N, Kaneko Y, Ohki M. t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. Proc Natl Acad Sci USA 1991; 88: 10431-10434.
9. Erickson P, Gao J, Chang K-S, Look T, Whisenant E, Raimondi S, Lasher R, Trujillo J, Rowly J, Drabkin H. Identification of break-points in t(8;21) acute myelogeous leukemia and isolation of a fusion transcript. AML1/ETO, with similarity to Drosophia segmentation gene, runt. Blood 1992; 80: 1825-1831.
10. Miyoshi H, Kozu T, Shimizu N, Enomoto K, Maseki N, Kaneko Y, Kamada N, Ohki M. The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript. EMBO J 1993; 12: 2715-2721.
11. Zhang D-E, Fujioka KI, Hetherington CJ, Shapiro LH, Chen HM, Look AT, Tenen DG. Identification of a region which directs monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1). Mol Cell Biol 1994; 14: 8085-8095.
12. Nuchprayoon I, Meyers S, Scott LM, Suzow J, Hiebert S, Friedman AD. PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2b/CBFb proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells. Mol Cell Biol 1994; 14: 5558-5568.
13. Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 1996; 84: 321-330.
14. Wang Q, Stacy T, Binder M, Marin-Padilla M, Sharpe AH, Speck NA. Distribution of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc Natl Acad Sci USA 1996; 93: 3444-3449.
15. Klampfer L, Zhang J, Zelenetz AO, Uchida H, Nimer SD. The AML1/ETO fusion protein activates transcription of BCL-2. Proc Natl Acad Sci USA 1996; 93: 14059-14064.
16. Ema H, Kitano K, Suda T, Sato T, Muroi K, Ohta M, Yoshida M, Sakamolo S, Eguchi M, Miura Y. In vitro differentiation of leukemia cells to eosinophils in the presence of interleukin-5 in two cases of acute myeloid leukemia with the translocation (8;21)(q22;q22). Blood 1990; 75: 350-356.
17. Lowenberg B, van Putten WLJ, Touw IP, Delwel R, Santini V. Autonomous proliferation of leukemic cells in vitro as a determinant of prognosis in adult acute myeloid leukemia. New Engl J Med 1993; 328: 614-619.
18. Tsujimoto Y, Finger LR, Yunis J, Nowell PC, Corcw CM. Cloning the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 1984; 226: 1097-1099.
19. Hockenbery D, Numerz G, Milliman C. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990; 348: 334-336.
20. Delia D, Aiello A, Soligo D, Fontanella E, Melani C, Pezzella F, Pierotti MA, Della Porta G. bcl-2 protooncogene expression in normal and neoplastic human myeloid cells. Blood 1992; 79: 1291-1298.
21. Bradbury DA, Russell NH. Comparative quantitative expression of bcl-2 by normal and leukaemic cells. Br J Haematol 1995; 91: 374-379.
22. Park JR, Bernstein ID, Hockenbey DM. Primitive human hematopoietic precursors express bcl-x but not bcl-2. Blood 1995; 86: 868-876.
23. Porwit-MacDonald A, Ivory K, Wilkinson S, Wheatley K, Wong L, Janossy G. Bcl-2 protein expression in normal bone marrow precursors and in acute myelogenous leukemia. Leukemia 1995; 9: 1191-1198.
24. Bradbury DA, Aldington S, Zhu Y-M, Russel NH. Down-regulation of bcl-2 in AML blasts by all-trans retinoic acid and its relationship to CD34 antigen expression. Br J Haematol 1996; 94: 671-675.
25. Asou H, Tashiro S, Hanamoto K, Otsuji A, Kita K, Kamada N. Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosomal translocation. Blood 1991; 77: 2031-2036.
26. Kita K, Miwa H, Nakase K, Kawakami K, Kobayashi T, Shirakawa S, Tanaka I, Ohta C, Tsutani H, Oguma S, Kyo T, Dohy H, Kamada N, Nasu K, Uchino H (The Japanese Cooperative Group of Leukemia/Lymphoma). Clinical importance of CD7 expression in acute myelocytic leukemia. Blood 1995; 81: 2399-2405.
27. Masuya M, Kita K, Shimizu N, Ohishi K, Katayama N, Sekine T, Otsuji A, Miwa H, Shirakawa S. Biological characteristics of acute leukemia following myelodysplastic syndrome. Blood 1993; 81: 3388-3394.
28. Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983; 11: 1475-1489.
29. Wilson BE, Mochon E, Boxer LM. Induction of bcl-2 expression by phosphorylated CREB proteins during B cell activation and rescue from apoptosis. Mol Cell Biol 1996; 16: 5546-5556.
30. Carey JO, Posekany KJ, deVente JE, Pettite GR, Kirk Ways D. Phorbol ester-stimulated phosphorylation of PU.1: association with leukemic cell growth inhibition. Blood 1996; 87: 4316-4324.
31. Ema H, Suda T, Miura T, Nakauchi H. Colony formation of clone-sorted human hematopoietic progenitors. Blood 1990; 75: 1941-1946.
32. + cells. Blood 1992; 80: 429-436.
33. Young JC, Varma A, DiGiusto D, Backer MP. Retention of quiescent hematopoietic cells with high proliferative potential during ex vivo stem cell culture. Blood 1996; 87: 545-556.
34. Uchida N, He D, Friera AM, Reitsma M, Sasaki D, Chen B, Tsukamoto A. The unexpected G0/G1 cell cycle status of mobilized hematopoietic stem cells from peripheral blood. Blood 1997; 89: 465-472.
35. Sanz C, Benito A, Silva M, Albella B, Richard C, Carlos SJ, Insunza A, Bueren J, Fernandez-Luna J. The expression of Bcl-x is downregulated during differentiation of human hematopoietic progenitor cells along the granulocyte but not the monocyte/macrophage lineage. Blood 1997; 89: 3199-3204.
36. O-Reily LA, Huang DCS, Strasser A. The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry. EMBO J 1996; 15: 6979-6990.
37. Mazel S, Burtrum D, Petrie HT. Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death. J Exp Med 1996; 183: 2219-2226.
38. Vario G, Innes KM, Adams JM. Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival. Oncogene 1996; 13: 1511-1519.
39. Bradbury D, Y-M Zhu, N Russell. Regulation of bcl-2 expression and apoptosis in acute myeloblastic leukaemia cells by granulocyte-macrophage colony-stimulating factor. Leukemia 1994; 8: 786-791.
40. Carson WE, Haldar S, Baiocchi RA, Croce CM, Caligiuri MA. The c-kit ligand suppresses apoptosis of human natural killer cells through upregulation of bcl-2. Proc Natl Acad Sci USA 1994; 91: 7553-7557.
41. Marvel J, Perkin GR, Rivas AL, Collins MKL. Growth factor starvation of bcl-2 overexpressing murine bone marrow cells induced refractoriness to IL-3 stimulation of proliferation. Oncogene 1994; 9: 1117-1122.
42. Suda T, Suda J, Ogawa M, Ihle JN. Permissive role for interleukin 3 (IL-3) in proliferation and differentiation of multipotential hematopoietic progenitors in culture. J Cell Physiol 1985; 124: 182-190.
43. Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood 1993; 81: 2844-2853.
44. Nishii K, Kita K, Nadim M, Miwa H, Ohishi K, Yamaguchi M, Shirakawa S. Expression of interleukin-5 receptors on acute myeloid leukaemia cells: association with immunophenotype and karyotype. Br J Haematol 1995; 91: 169-172.
45. Kitamura T, Sato N, Arai K-I, Miyajima A. Expression cloning of the human IL-3 receptor cDNA reveals a shared subunit for the human IL-3 and GM-CSF receptors. Cell 1991; 66: 1165-1174.
46. Tavernier J, Devos R, Cornells S, Tuypens T, Van der Hyden J, Fiers W, Plaetinck G. A human high affinity interleukin-5 receptor (IL5R) is composed of an IL-5-specific β chain shared with the receptor for GM-CSF. Cell 1991; 66: 1175-1184.
47. Fairbairn LJ, Cowling GJ, Reipert BM, Dexter TM. Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 1993; 74: 823-832.
48. Gubina E, Rinaudo MS, Szallasi Z, Blumberg PM, Mufson RA. Overexpression of protein kinase C isoform E but not S in human interleukin-3-dependent cells suppresses apoptosis and induces bcl-2 expression. Blood 1998; 91: 823-829.
49. Tanaka T, Kurokawa M, Ueki K, Tanaka K, Imai Y, Mitani K, Okazaki K, Sagata N, Yazaki Y, Shibata Y, Kadowaki T, Hirai H. The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability. Mol Cell Biol 1996; 16: 3967-3979.