Infrequent germ-line mutation of the E-cadherin gene in Japanese familial gastric cancer kindreds

Clinical Cancer Research

Volumn 5, Issue 6, 1999, Pages 1445-1447

  Iida, Satoru ^a   Akiyama, Yoshimitsu ^a   Ichikawa, Wataru ^a   Yamashita, Toshiki ^a   Nomizu, Tadashi ^b   Nihei, Zenro ^a   Sugihara, Kenichi ^a   Yuasa, Yasuhito ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b HOSHI GENERAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

UVOMORULIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER SUSCEPTIBILITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC RISK; GERM LINE; HUMAN; HUMAN TISSUE; JAPAN; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; STOMACH CANCER;

ADOLESCENT; ADULT; AGED; CADHERINS; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; JAPAN; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; STOMACH NEOPLASMS;

EID: 0033011770     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Fuchs, C. S., and Mayer, R. J. Gastric carcinoma. N. Engl. J. Med., 333: 32-41, 1995.
2. Zanghieri, G., Di Gregorio, C., Sacchetti, C., Fante, R., Sassatelli, R., Cannnizzo, G., Carriero, A., and Ponz de Leon, M. Familial occurrence of gastric cancer in the 2-year experience of a population-based registry. Cancer (Phila.), 66: 2047-2051, 1990.
3. La Vecchia, C., Negri, E., Franceschi, S., and Gentile, A. Familial history and the risk of stomach and colorectal cancer. Cancer (Phila.), 70: 50-55, 1992.
4. Kikuchi, S., Nakajima, T., Nishi, T., Kobayashi, O., Konishi, T., Inaba, Y., Wada, O., Satou, H., Ishibashi, T., Ichikawa, S., Okamoto, N., Hirata, T., Kubo, T., Sato, N., Miki, K., and Myoga, A. Association between family history and gastric carcinoma among young adults. Jpn. J. Cancer Res., 87: 332-336, 1996.
5. Aaltonen, L. A., Peltomäki, P., Leach, F. S., Sistonen, P., Pylkkänen, L., Mecklin, J. P., Järvinen, H., Powell, S. M., Jen, J., Hamilton, S. R., Petersen, G. M., Kinzler, K. W., Vogelstein, B., and de la Chapelle, A. Clues to the pathogenesis of familial colorectal cancer. Science (Washington DC), 260: 812-816, 1993.
6. Wu, C., Akiyama, Y., Imai, K., Miyake, S., Nagasaki, H., Oto, M., Okabe, S., Iwama, T., Mitamura, K., Masumitsu, H., Nomizu, T., Baba, S., Maruyama, K., and Yuasa, Y. DNA alterations in cells from hereditary non-polyposis colorectal cancer patients. Oncogene, 9: 991-994, 1994.
7. Kinzler, K. W., and Vogelstein, B. Lessons from hereditary colorectal cancer. Cell, 87: 159-170, 1996.
8. Akiyama, Y., Sato, H., Yamada, T., Nagasaki, H., Tsuchiya, A., Abe, R., and Yuasa, Y. Germ-line mutation of the hMSH6/GTBP gene in atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res., 57: 3920-3923, 1997.
9. Peltomäki, P., Lothe, R. A., Aaltonen, L. A., Pylkkänen, L., Nyström-Lahti, Seruca, R., David, L., Holm, R., Ryberg, D., Haugen, A., Brogger, A., Borresen, A. L., and de la Chapelle, A. Microsatellite instability is associated with tumors that characterize the hereditary nonpolyposis colorectal carcinoma syndrome. Cancer Res., 53: 5853-5855, 1993.
10. Han, H-J., Yanagisawa, A., Kato, Y., Park, J-G., and Nakamura, Y. Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res., 53: 5087-5089, 1993.
11. Rhyu, M-G., Park, W-S., and Meltzer, S. J. Microsatellite instability occurs frequently in human gastric carcinoma. Oncogene, 9: 29-32, 1994.
12. Zelada-Hedman, M., Iselius, L., Gunven, P., Weger, A., Nordenskjold, M., Skoog, L., and Lindblom, A. Genetic rearrangements in sporadic and familial gastric carcinomas detected with microsatellite markers. Eur. J. Surg. Oncol., 20: 667-673, 1994.
13. Sasaki, A., Nagashima, M., Shiseki, M., Katai, H., Maruyama, K., Iwanaga, R., Akiyama, Y., Yuasa, Y., and Yokota, J. Microsatellite instability in gastric cancer prone family. Cancer Lett., 99: 169-175, 1996.
14. Akiyama, Y., Nagasaki, H., Nihei, Z., Iwama, T., Nomizu, T., Utsunomiya, J., and Yuasa, Y. Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers. Jpn. J. Cancer Res., 87: 595-601, 1996.
15. Ottini, L., Palli, D., Falchetti, M., D'Amico, C., Amorosi, A., Saieva, C., Calzolari, A., Cimoli, F., Tatarelli, C., De Marchis, L., Masala, G., Mariani-Costantini, R., and Cama, A. Microsatellite instability in gastric cancer is associated with tumor location and family history in a high-risk population from Tuscany. Cancer Res., 57: 4523-4529, 1997.
16. Shinmura, K., Yin, W., Isogaki, J., Saitoh, K., Kanazawa, K., Koda, K., Yokota, J., Kino, I., Arai, T., and Sugimura, H. Stage-dependent evaluation of microsatellite instability in gastric carcinoma with familial clustering. Cancer Epidemiol. Biomark. Prev., 6: 693-697, 1997.
17. Guilford, P., Hopkins, J., Harraway, J., McLeod, M., McLeod, N., Harawira, P., Taite, H., Scoular, R., Miller, A., and Reeve, A. E. E-cadherin germline mutations in familial gastric cancer. Nature (Lond.), 392: 402-405, 1998.
18. Takeichi, M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science (Washington DC), 251: 1451-1455, 1991.
19. Shiozaki, H., Tahara, H., Oka, H., Miyata, M., Kobayashi, K., Tamura, S., Iihara, K., Doki, Y., Hirano, S., Takeichi, M., and Mori, T. Expression of immunoreactive E-cadherin adhesion molecules in human cancers. Am. J. Pathol., 139: 17-23, 1991.
20. Schipper, J. H., Frixen, U. H., Behrens, J., Unger, A., Jahnke, K., and Birchmeier, W. E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res., 51: 6328-6337, 1991.
21. Mayer, B., Johnson, J. P., Letil, F., Jauch, K. W., Heiss, M. M., Schildberg, F. W., Birchmeier, W., and Funke, I. E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res., 53: 1690-1695, 1993.
22. Oda, T., Kanai, Y., Oyama, T., Yoshiura, K., Shimoyama, Y., Birchmeier, W., Sugimura, T., and Hirohashi, S. E-cadherin gene mutations in human gastric carcinoma cell lines. Proc. Natl. Acad. Sci. USA, 91: 1858-1862, 1994.
23. Becker, K. F., Atkinson, M. J., Reich, U., Becker, I., Nekarda, H., Siewert, J. R., and Höfler, H. E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res., 54: 3845-3852, 1994.
24. Muta, H., Noguchi, M., Kanai, Y., Ochiai, A., Nawata, H., and Hirohashi, S. E-cadherin gene mutations in signet ring cell carcinoma of the stomach. Jpn. J. Cancer Res., 87: 843-848, 1996.
25. Lynch, H. T., and Smyrk, T. Hereditary nonpolyposis colorectal cancer (Lynch syndrome). Cancer (Phila.), 78: 1149-1167, 1996.
26. Blin, N., and Stafford, D. W. A general method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res., 3: 2303-2308, 1976.
27. Goelz, S. E., Hamilton, S. R., and Vogelstein, B. Purification of DNA from formaldehyde-fixed and paraffin-embedded human tissue. Biochem. Biophys. Res. Commun., 130: 118-126, 1985.
28. Berx, G., Cleton-Jansen, A-M., Nollet, F., de Leeuw, W. J. F., van de Vijver, M. J., Cornelisse, C., and van Roy, F. E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. EMBO J., 14: 6107-6115, 1995.
29. Oto, M., Miyake, S., and Yuasa, Y. Optimization of nonradioisotopic single strand conformation polymorphism analysis with a conventional minislab gel electrophoresis apparatus. Anal. Biochem., 213: 19-22, 1993.
30. Laurén, P. The two histological main types of gastric carcinoma: diffuse and so called intestinal-type of carcinoma. Acta Pathol. Microbiol. Scand., 64: 31-49, 1965.
31. Risinger, J. I., Berchuck, A., Kohler, M. F., and Boyd, J. Mutation of the E-cadherin gene in human gynecologic cancers. Nat. Genet., 7: 98-102, 1994.
32. Keller, G., Grimm, V., Vogelsang, H., Bischoff, P., Mueller, J., Siewert, J. R., and Höfler, H. Analysis for microsatellite instability and mutations of the DNA mismatch repair gene hMLHI in familial gastric cancer. Int. J. Cancer, 68: 571-576, 1996.
33. Gayther, S. A., Gorringe, K. L., Ramus, S. J., Huntsman, D., Roviello, F., Grehan, N., Machado, J. C., Pinto, E., Seruca, R., Hailing, K., MacLeod, P., Powell, S. M., Jackson, C. E., Ponder, B. A. J., and Caldas, C. Identification of germ-line E-cadherin mutations in gastric cancer families of European origin. Cancer Res., 58: 4086-4089, 1998.