Truncated growth hormone receptor isoforms

Acta Paediatrica, International Journal of Paediatrics, Supplement

Volumn 88, Issue 428, 1999, Pages 164-166

  Ross, R J M ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Cirrhosis; Growth hormone; Growth hormone insensitivity; Growth hormone receptor; Growth hormone resistance; Truncated growth hormone receptor

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE BINDING PROTEIN; GROWTH HORMONE RECEPTOR;

ALTERNATIVE RNA SPLICING; CONFERENCE PAPER; EXON; GENE MUTATION; HORMONE RECEPTOR INTERACTION; HORMONE RESISTANCE; LIVER CIRRHOSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHORT STATURE; SIGNAL TRANSDUCTION;

EID: 0033008421     PISSN: 08035326     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (10)

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7. Amit T, Bergman T, Dastot F, Youdim MBH, Amselem S, Hochberg Z. A membrane-fixed, truncated isoform of the human growth hormone receptor. J Clin Endocrinol Metab 1997;82:3813-17
8. Ayling RM, Ross R, Towner P, Von Laue S, Finidori J, Moutoussamy S, et al. A dominant negative mutation of the growth hormone receptor causes familial short stature. Nat Genet 1997;16:13-14
9. Iida K, Takahashi Y, Kaji H, Nose O, Okimura Y, Abe H, et al. Growth hormone (GH) insensitivity syndrome with high serum GH-binding protein levels caused by a heterozygous splice site mutation of the GH receptor gene producing a lack of intracellular domain. J Clin Endocrinol Metab 1998;83:531-7
10. Shen XY, Holt RIG, Miell JP, Justice S, Portmann B, Postel-Vinay MC, et al. Cirrhotic liver expresses low levels of the full-length and truncated growth hormone receptors. J Clin Endocrinol Metab 1998;83:2532-8