Cellular and subcellular expression of Golf/Gs and Gq/G11 α-subunits in rat pancreatic endocrine cells

Journal of Histochemistry and Cytochemistry

Volumn 47, Issue 3, 1999, Pages 289-302

  Astesano, Any ^a   Regnauld, Karine ^a   Ferrand, Nathalie ^a   Gingras, Diane ^b   Bendayan, Moïse ^b   Rosselin, Gabriel ^a   Emami, Shahin ^a  

^a CENTRE DE RECHERCHE SAINT ANTOINE   (France)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

B cell; Confocal microscopy; Diabetes; Electron microscopy; G proteins; Golf s ; Gq 11 ; Immunocytochemistry; In situ hybridization; Islets of Langerhans; Signal transduction

Indexed keywords

STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ACINAR CELL; ALPHA CHAIN; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL ULTRASTRUCTURE; CELLULAR DISTRIBUTION; FEMALE; GOLGI COMPLEX; HORMONE RELEASE; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ROUGH ENDOPLASMIC RETICULUM; SECRETORY GRANULE;

ANIMALIA;

EID: 0032999725     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549904700303     Document Type: Article

References (56)

1. Abdel-Halim SM, Guenifi A, He B, Yang B, Mustafa M, Hojeberg B, Hillert J, Bakhiet M, Efendic S (1998) Mutations in the promoter of adenylyl cyclase (AC)-III gene, over expression of AC-III mRNA, and enhanced cAMP generation in islets from the spontaneously diabetic GK rat model of type 2 diabetes. Diabetes 47:498-504
2. Anteunis A, Astesano A, Portha B, Hejblum G, Rosselin G (1989) Ultrastructural analysis of VIP internalization in rat β and acinar cells in situ. Am J Physiol 256:G689-697
3. Astesano A, Ferrand N, Arimura A, Bendayan M, Rosselin G, and Emami S (1997) Diversity of the transduction system expression in pancreatic cells. Diabetologia 40:A137
4. Astesano A, Ferrand N, Bendayan M, Rosselin G (1996) Sub-cellular localization of G-protein a subunits in adult rat islets. Ann NY Acad Sci 805:549-554
5. Bakalyar HA, Reed RR (1990) Identification of a specialized adenylyl cyclase that may mediate odorant detection. Science 250: 1403-1406
6. Barakat A, Skoglund G, Boissard C, Rosselin G, Marie JC (1994) Calcitonin gene-related peptide and islet amyloid polypeptide stimulate insulin secretion in RINm5F cells through a common receptor coupled to a generation of cAMP. Biosci Rep 14:1-13
7. Bataille D, Besson J, Bastard C, Laburthe M, Rosselin G (1977) Specificity in hormones-receptor interaction: studies with insulin glucagon and vasoactive intestinal peptide (VIP) In Bonfils S, Fromageot P, Rosselin G, eds. Hormonal Receptors in Digestive Tract Physiology. Amsterdam, Elsevier, 113-123
8. Bendayan M (1995) Colloïdal gold post-embedding immunocytochemistry. Prog Histochem Cytochem 29:1-163
9. Boissard C, Marie JC, Phan HH, Chastre E, Rosselin G (1996) Effect of PACAP, VIP, glucagon and GLP1 on cAMP production and insulin release by HIT-T15 cells is passage dependent. Ann NY Acad Sci 805:634-639
10. Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
11. Colombo MI, Mayorga LS, Nishimoto I, Ross EM, Stahl PD (1994) Gsα regulation of endosome fusion suggests a role for signal transduction pathways in endocytosis. J Biol Chem 269:14919-14923
12. Cormont M, Le Marchand-Brustel Y, Van Obberghen E, Spiegel AM, Sharp GWG (1991) Identification of G protein α-subunits in RINm5F cells and their selective interaction with galanin receptor. Diabetes 40:1170-1176
13. Dachicourt N, Serradas P, Giroix MH, Gangnerau MN, Portha B (1996) Decreased glucose-induced cAMP and insulin release in islets of diabetic rats: reversal by IBMX, glucagon, GIP. Am J Physiol 271:E725-732
14. Dagerlind A, Friberg K, Bean AJ, Hökfelt T (1992) Sensitive messenger RNA detection using unfixed tissue. Combined radioactive and non-radioactive in situ hybridization histochemistry. Histochemistry 98:1:39-49
15. Denker SP, MacCaffery JM, Palade GE, Insel PA, Farquhar MG (1996) Differential distribution of α subunits and βγ subunits of heterotrimeric G proteins on Golgi membranes of the exocrine pancreas. J Cell Biol 133:1027-1040
16. Efrat S, Linde S, Kofod H, Spector D, Delannoy M, Grant S, Hanahan D, Baekkeskov S (1988) Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene oncogene. Proc Natl Acad Sci USA 85:903 7-9041
17. Emami S, Regnauld K, Ferrand N, Astesano A, Pessah M, Phan H, Garel JM, Rosselin G (1998) Molecular diversity of the adenylyl cyclase coupled signaling in pancreatic islet cells. Proc 3rd Int Symp VIP, PACAP, and related peptides. Ann NY Acad Sci 865: 118-131
18. Ferrand N, Astesano A, Rosselin G (1996) Evidence of G-protein αs and αolf subunits in developing human pancreas. Ann NY Acad Sci 805:563-569
19. Fridolf T, Ahren B (1993) Effects of glucagon like peptide-1 (7-36) amide on the cytoplasmic Ca(2+)-concentration in rat islet cells. Mol Cell Endocrinol 96:85-90
20. Gazdar AF, Chick WL, Oie HK, Sims HL, King DL, Weir GC, Lauris V (1980) Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor. Proc Natl Acad Sci USA 77:3519-3523
21. Gilman AG (1990) Regulation of adenylyl cyclase by C proteins. Adv Second Messenger Phosphoprotein Res 24:51-57
22. Hansen SH, Casanova JE (1994) Gsα stimulates transcytosis and apical secretion in MDCK cells through cAMP and protein kinase A. J Cell Biol 126:678-687
23. Herve D, Rogard M, Levi-Strauss M (1995) Molecular analysis of the multiple Golf α subunit mRNAs in the rat brain. Mol Brain Res 32:125-134
24. Itoh H, Kozasa T, Nagata S, Nakamura S, Katada T, Ui M, Iwai S, Ohtsukae E, Kawasaki H, Suzuki K, Kaziro V (1986) Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gsα, Gi and Go from rat brain. Proc Natl Acad Sci USA 83:3776-3780
25. Jarrousse C, Rosselin G (1975) Interaction of amino acids and cyclic AMP on the release of insulin and glucagon by newborn rat pancreas. Endocrinology 1:168-177
26. Jones DT, Reed RR (1989) Golf: an olfactory neuron specific G-protein involved in odorant signal transduction. Science 244: 790-795
27. Klinteberg KA, Karlsson S, Ahren B (1996) Signaling mechanisms underlying the insulinotropic effect of pituitary adenylate cyclase-activating polypeptide in HIT-T15 cells. Endocrinology 137:2791-2798
28. Konrad RJ, Young RA, Record RD, Smith RM, Butkerait P, Manning D, Jarett L, Wolf A (1995) The hererotrimeric G-prorein Gi is localized to the insulin secretory granules of β cells and is involved in insulin exocyosis. J Biol Chem 270:12869-12876
29. Kowluru, Li G, Metz SA (1997) Glucose activates the carboxyl methylation of γ subunits of trimeric GTP-binding proteins in pancreatic B cells. J Clin Invest 100:1596-1610
30. Kowluru A, Seavey SE, Rhodes CJ, Metz S (1996) A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent β cells. Biochem J 313:97-107
31. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
32. Leech CA, Habener JF (1996) Signal transduction of PACAP and GLP-1 in pancreatic B cells. Ann NY Acad Sci 805:81-93
33. 2+ entry in rat portal vein myocytes. J Biol Chem 272:5261-5268
34. Maletti M, Portha B, Carlquist M, Kergoat M, Laburthe M, Marie JC, Rosselin G (1984) Evidence for a characterization of specific high affinity binding sites for the gastric inhibitory polypepride in pancreatic B-cells. Endocrinology 115:1324-1325
35. Marie JC, Rosselin G, Skoglund G (1996) Pancreatic B-cell receptors and G proteins coupled to adenylyl cyclase. Ann NY Acad Sci 805:121-132
36. Menco BPM, Bruch RC, Dau B, Danho W (1992) Ultrastructural localization of olfactory transduction components: the G protein subunit Golfα and type III adenylyl cyclase. Neuron 8:441-453
37. Milligan G, Carr C, Gould GW, Mullaney I, Lavan BE (1991) Agonist-dependent, cholera toxin-catalyzed ADP-ribosylation of pertussis toxin-sensitive G proteins following transfection of the human α2-C10 adrenergic receptor into rat 1 fibroblasts. Evidence for the direct interaction of a single receptor with two pertussis toxin-sensitive G-proteins, Gi2, Gi3. J Biol Chem 266:6447-6455
38. Muller L, Picart R, Barret A, Bockaert J, Homburger V, Tougard C (1994) Identification of multiple subunits of heterotrimeric G proteins on the membrane of secretory granules in rat prolactin anterior pituitary cells. Mol Cell Neurol 5:556-566
39. Neer EJ (1995) Heterotrimeric G proteins: organizers of transmembrane signals. Cell 80:249-257
40. Ohnishi H, Ernst SA, Yule DI, Baker CW, Williams JA (1997) Heterotrimeric G-protein Gq/11 localized on pancreatic zymogen granules is involved in calcium-regulated amylase secretion. J Biol Chem 272:16056-16061
41. Phan H, Pessah M, Boissard C, Ferrand N, Astesano A, Emami S, Malaisse WJ, Yanaihara N, Rosselin G (1997) Functional and immunohistological species specificity of Golfα and Giα expression in pancreas, islets and B-cells. Diabetologia 40:A106
42. Piiper A, Stryjek-Kaminska D, Klengel R, Zeuzem S (1997) CCK, carbachol, and bombesin activate distinct PLC-β isoenzymes via Gq/11 in rat pancreatic acinar membranes. Am J Physiol 272: G135-140
43. Porte D (1967) A receptor mechanism for the inhibition of insulin release by epinephrine in man. J Clin Invest 46:86-94
44. Powers AC, Efrat S, Mojsov S, Spector D, Habener JF, Hanahan D (1990) Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor. Diabetes 39:406-414
45. Rosselin G, Emami S (1997) Growth and differentiation of the islet cells in neonates. In Sarvetnick N, ed. Pancreatic Growth and Regeneration. Review Article. Basel, Karger Landes Systems, 44-97
46. Scopsi L, Wang BL, Larsson LI (1986) Nonspecific immunocytochemical reactions with certain neurohormonal peptides and basic peptide sequences. J Histochem Cytochem 34:1469-1475
47. Skoglund G, Basmaciogullari A, Rosselin G (1995) G-proteins are cell specifically distributed in the Langerhans islets of the rat. Diabetologia 38:449
48. Skoglund G, Rosselin G (1993) Receptor-coupled information processes in the regulation of pancreatic B-cell functions by the alimentary tract. Biomed Res 14:21-51
49. Strathmann M, Simon MI (1990). G protein diversity: a distinct class of α subunits is present in vertebrates and invertebrates. Proc Natl Acad Sci USA 87:9113-9117
50. Tsu RC, Lai HW, Allen RA, Wong YH (1995) Differential coupling of the formyl peptide receptor to adenylate cyclase and phospholipase C by the pertussis toxin-insensitive Gz protein. Biochem J 309:331-339
51. Udrisar D, Rodbell M (1990) Microsomal and cytosolic fractions of guinea pig hepatocytes contain 100-KD GTP-binding proteins reactive with antisera against α subunits of stimulatory and inhibitory heterotrimeric GTP-binding proteins. Proc Natl Acad Sci USA 87:6321-6325
52. Walseth TF, Zhang HJ, Olson LK, Schroeder WA, Roberston RP (1989) Increase in Gs and cyclic AMP generation in HIT cells. Evidence that the 45-kDa-α subunit of Gs has greater functional activity than the 52-kDa-α subunit. J Biol Chem 264:21106-21111
53. Wilson BS, Komuro M, Farquhar MG (1994) Cellular variations in heterotrimeric G protein localization and expression in rat pituitary. Endocrinology 134:233-242
54. Yada T, Sakuruda M, Ihida K, Nakata M, Murata F, Arimura A, Kituchi M (1994) Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intrapancreatic regulator of insulin secretion from islet B-cells. J Biol Chem 269:1290-1293
55. Zigman JM, Westermark GT, Lamendola J, Boel H, Steiner DF (1993) Human Golfα: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system. Endocrinology 133:2508-2514
56. Zigman JM, Westermark GT, LaMendola J, Steiner DK (1994) Expression of cone transducin, Gzα, and other G-protein α-subunit messenger ribonucleic acids in pancreatic islets. Endocrinology 135:31-37