Inhaled beclomethasone dipropionate reverts tolerance to the protective effect of salmeterol on allergen challenge

Chest

Volumn 115, Issue 3, 1999, Pages 629-634

  Giannini, Daniele ^a,c   Bacci, Elena ^a   Dente, Federico L ^a   Di Franco, Antonella ^a   Vagaggini, Barbara ^a   Testi, Renato ^b   Paggiaro, Pierluigi ^a  

^a UNIVERSITY OF PISA   (Italy)

^b GSK   (Italy)

^c CISANELLO HOSPITAL   (Italy)

Author keywords

Allergen challenge; Asthma; Inhaled corticosteroids; Salmeterol; Tolerance; 2 agonist

Indexed keywords

ALLERGEN; BECLOMETASONE DIPROPIONATE; SALMETEROL;

ADULT; ALLERGIC ASTHMA; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DERMATOPHAGOIDES PTERONYSSINUS; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG POTENTIATION; DRUG TOLERANCE; FEMALE; FORCED EXPIRATORY FLOW; FORCED EXPIRATORY VOLUME; HUMAN; INHALATIONAL DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL;

EID: 0032996107     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.115.3.629     Document Type: Article

References (26)

1. 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. N Engl J Med 1992; 327:1198-1203
2. 2 Ramage L, Lipworth BJ, Ingram CG, et al. Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol. Respir Med 1994; 88:363-368
3. 3 Giannini D, Carletti A, Dente FL, et al. Tolerance to the bronchoprotective effect of salmeterol on allergen challenge. Chest 1996; 110:1452-1457
4. 4 Hui KPP, Conolly ME, Tashkin DP. Reversal of human lymphocyte β-adrenoceptor desensitization by glucocorticosteroids. Clin Pharmacol Ther 1982; 32:566-571
5. 2-adrenoceptor: accelerated restoration of β-adrenoceptor responsiveness by prednisone and ketotifen. J Clin Invest 1985; 76:1096-1101
6. 6 Davies AO, Lefkowitz RJ. In vitro desensitization of beta-adrenergic receptors in human neutrophils: attenuation by corticosteroids. J Clin Invest 1983; 71:565-571
7. 7 Ellul-Micallef R, Fenech FF. Effect of intravenous prednisolone in asthmatics with diminished adrenergic responsiveness. Lancet 1975; 2:1269-1271
8. 8 Booth H, Bish R, Walters J, et al. Salmeterol tachyphylaxis in steroid treated asthmatic subjects. Thorax 1996; 51:1100-1104
9. 9 National Heart, Lung, and Blood Institute. International consensus report on diagnosis and treatment of asthma. Eur Respir J 1992; 5:601-641
10. 10 Paggiaro PL, Dente FL, Talini D, et al. Pattern of airway response to allergen extract of Phleum pratensis in asthmatic patients during and outside the pollen season. Respiration 1990; 57:51-56
11. 1. Eur Respir J 1997; 10(suppl 24):39s-41s
12. 12 Siegel S, Castellan NJ. Nonparametric statistics for the behavioral sciences. 2nd ed. Milano, Italy: McGraw-Hill Libri Italia Rrl, 1992
13. 13 Anderson S, Seale JP, Ferris L, et al. An evaluation of pharmacotherapy for exercise-induced asthma. J Allergy Clin Immunol 1979; 64:612-624
14. 2 agonists. Thorax 1996; 51:1051-1056
15. 15 Newnham DM, McDevitt DG, Lipworth BJ. Bronchodilator subsensitivity after chronic dosing with eformoterol in patients with asthma. Am J Med 1994; 97:29-37
16. 16 Britton MG, Earnshaw JS, Palmer JBD. A 12 months comparison of salmeterol with salbutamol in asthmatic patients. Eur Respir J 1992; 5:1062-1067
17. 2-receptor function and inflammatory cells. Allergy 1992; 47:477-483
18. 18 Karla S, Swystun VA, Bhagat R, et al. Inhaled corticosteroids do not prevent the development of tolerance to the bronchoprotective effect of salmeterol. Chest 1996; 109:953-956
19. 2-agonist and inhaled corticosteroid on airway responsiveness to allergen and methacholine. Am J Respir Crit Care Med 1995; 152:1485-1489
20. 2-agonist. Am J Respir Crit Care Med 1996; 154:1603-1607
21. 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderate severe stable asthmatics. Lancet 1997; 350:995-999
22. 22 Pizzichini MMM, Kidney JC, Wong BJO, et al. Effect of salmeterol compared with beclomethasone on allergen-induced asthmatic and inflammatory responses. Eur Respir J 1996; 9:449-455
23. 23 Dahl R, Johansson S-A. Importance of duration of treatment with inhaled budesonide on the immediate and late bronchial reaction. Eur J Respir Dis 1982; 63(suppl 122):167-175
24. 2-adrenoceptors function in asthmatic patients. Chest 1996; 109:342-347
25. 25 Greening AP, Ind PW, Northfield M, et al. Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Lancet 1994; 344:219-224
26. 26 Pauwels RA, Lofdhal CG, Postma DS, et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. N Engl J Med 1997; 337:1405-1411