A synergistic effect of serotonin transporter gene polymorphism and smoking in association with CHD

Thrombosis and Haemostasis

Volumn 81, Issue 6, 1999, Pages 853-856

  Arinami, Tadao ^a   Ohtsuki, Tsuyuka ^b   Yamakawa Kobayashi, Kimiko ^b   Amemiya, Hiroshi ^b   Fujiwara, Hideomi ^b   Kawata, Ken Ichi ^b   Ishiguro, Hiroki ^b   Hamaguchi, Hideo ^b  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

SEROTONIN; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER;

ADULT; AGED; ALLELE; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; DNA POLYMORPHISM; EXTRACELLULAR SPACE; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PRIORITY JOURNAL; PROMOTER REGION; SEROTONIN BLOOD LEVEL; THROMBOCYTE AGGREGATION; VASOCONSTRICTION;

EID: 0032994487     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1614586     Document Type: Article

References (17)

1. Fricchione GL, Bilfinger TV, Hartman A, Liu Y, Stefano GB. Neuroimmunologic implications in coronary artery disease. Adv Neuroimmunol 1996; 6: 131-42.
2. Hayreh SS, Piegors DJ, Heistad DD. Serotonin-induced constriction of ocular arteries in atherosclerotic monkeys. Implications for ischemic disorders of the retina and optic nerve head. Arch Ophthalmol 1997; 115: 220-8.
3. van den Berg EK, Schmitz JM, Benedict CR, Malloy CR, Willerson JT, Dehmer GJ. Transcardiac serotonin concentration is increased in selected patients with limiting angina and complex coronary lesion morphology. Circulation 1989; 79: 116-24.
4. Golino P, Piscione F, Benedict CR, Anderson HV, Cappelli-Bigazzi M, Indolfi C, Condorelli M, Chiariello M, Willerson JT. Local effect of serotonin released during coronary angioplasty. N Eng J Med 1994; 330: 523-8.
5. Geerling RA, de Bruin RW, Scheringa M, Bonthuis F, JN IJ, Marquet RL. Ketanserin reduces graft arteriosclerosis after allogeneic aorta transplantation in rats. J Cardiovasc Pharmacol 1996; 27: 307-11.
6. Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Muller CR, Hamer DH, Murphy DL. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996; 274: 1527-31.
7. Hanna GL, Himle JA, Curtis GC, Koram DQ, Weele JV, Leventhal BL, Cook EH Jr. Serotonin transporter and seasonal variation in blood serotonin in families with obsessive-compulsive disorder. Neuropsychopharmacology 1998; 18: 102-11.
8. Gelernter J, Kranzler H, Coccaro EF, Siever LJ, New AS. Serotonin Transporter Protein Gene Polymorphism and Personality Measures in African American and European American Subjects. Am J Psychiatry 1998; 155: 1332-8.
9. Jorm AF, Henderson AS, Jacomb PA, Christensen H, Korten AE, Rodgers B, Tan X, Easteal S. An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms. Mol Psychiatry 1998; 3: 449-51.
10. Mazzanti CM, Lappalainen J, Long JC, Bengel D, Naukkarinen H, Eggert M, Virkkunen M, Linnoila M, Goldman D. Role of the serotonin transporter promoter polymorphism in anxiety-related traits. Arch Gen Psychiatry 1998; 55: 936-40.
11. Yamanouchi Y, Arinami T, Tsuchiya S, Miyazaki R, Takaki H, Takano T, Hamaguchi H. Apolipoprotein E5 and E7 in apparently healthy Japanese males: frequencies and relation to plasma lipid levels. Jpn J Hum Genet 1994; 39: 315-25.
12. Terwilliger JD, Ott J. Handbook of human genetic linkage. Baltimore: The Johns Hopkins University Press 1994.
13. Delbruck SJ, Wendel B, Grunewald I, Sander T, Morris-Rosendahl D, Crocq MA, Berrettini WH, Hoehe MR. A novel allelic variant of the human serotonin transporter gene regulatory polymorphism. Cytogenet Cell Genet 1997; 79: 214-20.
14. Powell JT. Vascular damage from smoking: disease mechanisms at the arterial wall. Vasc Med 1998; 3: 21-8.
15. Gering SA, Folts JD. Exacerbation of acute platelet thrombus formation in stenosed dog coronary arteries with smoke from a non-tobacco-burning cigarette. J Lab Clin Med 1990; 116: 728-36.
16. Zhu BQ, Sun YP, Sievers RE, Isenberg WM, Glantz SA, Parmley WW. Passive smoking increases experimental atherosclerosis in cholesterol-fed rabbits. J Am Coll Cardiol 1993; 21: 225-32.
17. Lilienberg G, Venge P. Platelet adhesion in patients prone to arterial and venous thrombosis - the impact of gender, smoking and heredity. Scand J Clin Lab Invest 1998; 58: 279-86.