Colonization of microflora in mice: Mucosal defense against luminal bacteria

Journal of Gastroenterology

Volumn 34, Issue 1, 1999, Pages 54-60

  Fukushima, Kouhei ^a   Sasaki, Iwao ^a   Ogawa, Hitoshi ^a   Naito, Hiroo ^a   Funayama, Yuji ^a   Matsuno, Seiki ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Germ free conventionalization; Inflammatory bowel disease; Mucosal defense

Indexed keywords

MUCIN;

ABDOMINAL ABSCESS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; CECUM; CELL INFILTRATION; CONTROLLED STUDY; CRYPT CELL; DEFENSE MECHANISM; DIGESTIVE SYSTEM INFLAMMATION; ENTERITIS; EPITHELIUM HYPERPLASIA; FECES; GERMFREE ANIMAL; GOBLET CELL; HISTOCHEMISTRY; HISTOLOGY; INTESTINE EPITHELIUM CELL; INTESTINE FLORA; INTESTINE MUCOSA; MICROORGANISM; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; ULCERATIVE COLITIS;

ANIMALS; BACTERIA; COLON; COLONY COUNT, MICROBIAL; FOLLOW-UP STUDIES; GERM-FREE LIFE; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; INTESTINE, SMALL; MICE; MICE, INBRED ICR; MUCINS; PERIODIC ACID-SCHIFF REACTION; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 0032992303     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350050216     Document Type: Article

References (30)

1. Chadwick VS, Anderson RP. Microorganisms and their products in inflammatory bowel disease. In: MacDermott RP, Stenson WF, editors. Inflammatory bowel disease. New York: Elsevier Science, 1992:241-8.
2. Sadlack B, Mertz H, Schorle H, Schimpl A, Feller AC, Horak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993;75:253-61.
3. Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 1993;75:263-74.
4. Rath HC, Herfarth HH, Ikeda JS, Grenther WB, Hamm Jr TH, Balish E, et al. Normal luminal bacteria, especially bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human β2 microglobulin transgenic rats. J Clin Invest. 1996;98:945-53.
5. Gibson P, Rosella O. Interleukin 8 secretion by colonic crypt cells in vitro: Response to injury suppressed by butyrate and enhanced in inflammatory bowel disease. Gut 1995;37:536-43.
6. Kusugami K, Fukatsu A, Tanimoto M, Shinoda M, Haruta J, Kuroiwa A, et al. Elevation of interleukin-6 in inflammatory bowel disease is macrophage-and epithelial cell-dependent. Dig Dis Sci 1995;40:949-59.
7. Fukushima K, Sasaki I, Matsuno S, Fiocchi C. Decreased frequency of mitochondrial (Mt) DNA deletions in epithelial cells (EC) from active ulcerative colitis (UC) (abstract). Gastroenterology 1995;108:A872.
8. Roediger WEW. The colonie epithelium in ulcerative colitis: An energy-deficiency disease? Lancet 1980;II:712-5.
9. Mayer L, Eisenhardt D, Salomon P, Bauer W, Plous R, Piccinini L. Expression of class II molecules on intestinal epithelial cells in humans. Differences between normal and inflammatory bowel disease. Gastroenterology 1991;100:3-12.
10. Das KM, Dasgupta A, Mandal A, Geng X. Autoimmunity to cytoskeletal protein tropomyosin. A clue to the pathogenic mechanism for ulcerative colitis. J Immunol 1993;150:2487-93.
11. Sartor RB. Animal models of intestinal inflammation: relevance to inflammatory bowel disease. In: MacDermott RP, Stenson W, editors. Inflammatory bowel disease. New York: Elsevier 1992, pp. 337-54.
12. Maejima K, Tajima Y. Association of gnotobiotic mice with various organisms isolated from conventional mice. Jpn J Exp Med 1973;43:289-96.
13. Okayasu I, Hatakeyama S, Yamada M, Ohkusa T, Inagaki Y, Nakaya R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990;98:694-702.
14. Mowry RW. The special value of methods that colour both acidic and vicinyl hydroxyl groups in the histochemical study of mucins. with revised directions for the colloidal iron stain, the use of alcian blue 8Gx and their combination with the periodic acid Schiff reaction. Ann NY Acad Sci 1963;106:402-23.
15. Filipe MI. Mucins in the human gastrointestinal epithelium: a review. Invest Cell Pathol 1979;2:195-216.
16. Lev R, Spicer SS. Specific staining of sulphate groups with alcian blue at low pH. J Histochem Cytochem 1964;12:309.
17. Sharma R, Schumacher U, Ronaasen V, Coates M. Rat intestinal mucosal responses to a microbial flora and different diets. Gut 1995;36:209-14.
18. Shorter RG, McGill DB, Bahn RC. Cytotoxicity of mononuclear cells for autologous colonie epithelial cells in colonic diseases. Gastroenterology 1984;86:13-22.
19. Morris GP, Beck PL, Herridge MS, Depew WT, Szewczuk MR, Wallace JL. Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989;96:795-803.
20. Sartor RB, Cromartie WJ, Powell DW, Schwab JH. Granulomatous enterocolitis induced in rats by purified bacterial cell wall fragments. Gastroenterology 1985;89:587-95.
21. Kent TH, Cardelli RM, Stamier FW. Small intestinal ulcers and intestinal flora in rats given indomethacin. Am J Pathol 1969;34:237-45.
22. MacPherson BR, Pfeiffer CJ. Experimental production of diffuse colitis in rats. Digestion 1978;17:135-50.
23. Sharon P, Stenson WF. Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease. Gastroenterology 1985;88:55-63.
24. Hodgson HJF, Potter BJ, Skinner J, Jewell DP. Immune-complex mediated colitis in rabbits. Gut 1978;19:225-32.
25. Maejima K, Sasaki J, Shimoda K, Kurosawa T. Bacterial flora of ex-germ free mice after oral inoculation of feces from various species of conventional animals. Exp Anim 1981;30: 157-60.
26. Piotrowski J, Murty VL, Czajkowski A, Slomiany A, Yotsumoto F, Majka J. Association of salivary bacterial aggregating activity with sulfomucin. Biochem Mol Biol Int 1994;32:713-21.
27. Mantle M, Husar SD. Binding of Yersinia enterocolitica to purified, native small intestinal mucins from rabbits and human involves interactions with the mucin carbohydrate moiety. Infect Immun 1994;62:112-8.
28. Ravidin JI, John JE, Johnston LI, Innes DJ, Guerrant RL. Adherence of Entamoeba histolytica to rat and human colonic mucosa. Infect Immunol 1985;48:292-7.
29. Matsumoto S, Setoyama H, Umesaki Y. Differential induction of major histocompatibility complex molecules on mouse intestine by bacterial colonization. Gastroenterology 1992;103:1777-82.
30. Uribe A, Alam M, Johanson O, Midtvedt T, Theodorsson E. Microflora modulates endocrine cells in the gastrointestinal mucosa of the rat. Gastroenterology 1994;107:1259-69.