Adrenocorticotropic hormone secretion in rats induced by stimulation with serotonergic compounds

Journal of Neuroendocrinology

Volumn 11, Issue 4, 1999, Pages 283-290

  Jørgensen, Henrik ^a   Knigge, U ^b   Kjaer A ^b   Warberg, J ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NONE

Author keywords

ACTH; Neuroendocrine regulation; Rats; Serotonin; Serotonin receptors

Indexed keywords

1 ISOPROPYL 6 METHYLERGOLINE 8 CARBOXYLIC ACID 2 HYDROXY 1 METHYLPROPYL ESTER; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 5 CARBAMOYLTRYPTAMINE; 5 HYDROXYTRYPTOPHAN; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; 6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; CORTICOTROPIN; FLUOXETINE; KETANSERIN; METHYSERGIDE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N ACETYLSEROTONIN; ONDANSETRON; SEROTONIN; SEROTONIN 1 AGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 2 AGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN DERIVATIVE; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; TROPISETRON;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; CORTICOTROPIN RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

5-HYDROXYTRYPTOPHAN; ADRENOCORTICOTROPIC HORMONE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; RATS; RATS, WISTAR; SEROTONIN; SEROTONIN AGENTS;

EID: 0032986099     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.1999.00328.x     Document Type: Article

References (45)

1. Vale W, Rivier C, Yang L, Minick S, Guillemin R. Effects of purified hypothalamic corticotropin-releasing factor and other substances on the secretion of adrenocorticotropin and beta-endorphin-like immunoactivities in vitro. Endocrinology 1978; 103: 1910-1915.
2. Palkovits M. Anatomy of neural pathways affecting CRH secretion. Ann NY Acad Sci 1987; 512: 139-148.
3. Antoni FA. Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of 41-residue corticotropin-releasing factor. Endocr Rev 1986; 7: 351-378.
4. Mezey E, Young WS, Siegel RE, Kovacs K. Neuropeptides and neurotransmitters involved in regulation of corticotropin-releasing factor-containing neurons in the rat. Prog Brain Res 1987; 72: 119-127.
5. Calogero AE, Bernardini R, Margioris AN, Bagdy G, Gallucci WT, Munson PJ, Tamarkin L, Tomai TP, Brady L, Gold PW, Chorousos GP. Effects of serotonergic agonists and antagonists on corticotropin-releasing hormone secretion by explanted rat hypothalami. Peptides 1989; 10: 189-200.
6. Liposits Z, Phelix C, Paull WK. Synaptic interaction of serotonergic axons and corticotropin releasing factor (CRF) synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. A light and electron microscopic immunocytochemical study. Histochemistry 1987; 86: 541-549.
7. Sawchenko PE, Swanson LW, Steinbusch HW, Verhofstad AA. The distribution and cells of origin of serotonergic inputs to the paraventricular and supraoptic nuclei of the rat. Brain Res 1983; 277: 355-360.
8. Calogero AE, Bagdy G, Burrello N, Polosa P, D'Agata R. Role for serotonin 3 receptors in the control of adrenocorticotropic hormone release from rat pituitary cell cultures. Eur J Endocrinol 1995; 133: 251-254.
9. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR. Mylecharane EJ, Saxena PR, Humphrey PP. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin). Pharmacol Rev 1994; 46: 157-203.
10. Gartside SE, Cowen PJ. Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors. Eur J Pharmacol 1990; 179: 103-109.
11. Lorens SA, Van de Kar LD. Differential effects of serotonin (5-HT1A and 5-HT2) agonists and antagonists on renin and corticosterone secretion. Neuroendocrinology 1987; 45: 305-310.
12. Van de Kar LD. Neuroendocrine pharmacology of serotonergic (5-HT) neurons Ann Rev Pharmacol Toxicol 1991; 31: 289-320.
13. Calogero AE, Bagdy G, Szemeredi K, Tartaglia ME, Gold PW, Chrousos GP. Mechanisms of serotonin receptor agonist-induced activation of the hypothalamic-pituitary-adrenal axis in the rat. Endocrinology 1990; 126: 1888-1894.
14. Hoyer D. Functional correlates of serotonin 5-HT1 recognition sites. J Recept Res 1988; 8: 59-81.
15. Spinedi E, Gaillard RC. Stimulation of the hypothalamo-pituitary-adrenocortical axis by the central serotonergic pathway: involvement of endogenous corticotropin-releasing hormone but not vasopressin. J Endocrinol Invest 1991; 14: 551-557.
16. Smythe GA, Gleeson RM, Stead BM. Mechanisms of 5-hydroxy-L-tryptophan-induced adrenocorticotropin release: a major role for central noradrenergic drive. Neuroendocrinology 1988; 47: 389-397.
17. van Wijngaarden I, Tulp MT, Soudijn W. The concept of selectivity in 5-HT receptor research. Eur J Pharmacol 1990; 188: 301-312.
18. Bluet Pajot MT, Mounier F, di Sciullo A, Schmidt B, Kordon C. Differential sites of action of 8OHDPAT, a 5HT1A agonist, on ACTH and PRL secretion in the rat. Neuroendocrinology 1995; 61: 159-166.
19. 1A autoreceptor blockade: behavioral effect and corticosterone secretion in rats. Society for Neuroscience 1997; 23: 406-406.
20. Hjorth S, Westlin D, Bengtsson HJ. WAY100635-induced augmentation of the 5-HT-elevating action of citalopram: relative importance of the dose of the 5-HT1A (auto) receptor blocker versus that of the 5-HT reuptake inhibitor. Neuropharmacology 1997; 36: 461-465.
21. Gardier AM, Malagie I, Trillat AC, Jacquot C, Artigas F. Role of 5-HT1A autoreceptors in the mechanism of action of serotoninergic antidepressant drugs: recent findings from in vivo microdialysis studies. Fundam Clin Pharmacol 1996; 10: 16-27.
22. Mundey MK, Fletcher A, Marsden CA. Effects of 8-OHDPAT and 5-HT1A antagonists WAY 100135 and WAY 100635, on guinea-pig behaviour and dorsal raphe 5-HT neurone firing. Br J Pharmacol 1996; 117: 750-756.
23. Erlander MG, Lovenberg TW, Baron BM, de Lecea L, Danielson PE, Racke M, Slone AL, Siegel BW, Foye PE, Cannon K, Burns JE, Sutcliffe JG. Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc Natl Acad Sci USA 1993; 90: 3452-3456.
24. Ruat M, Traiffort E, Leurs R, Tardivel Lacombe, J, Diaz J, Arrang JM, Schwartz JC. Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation. Proc Natl Acad Sci USA 1993; 90: 8547-8551.
25. Baez M, Kursar JD, Helton LA, Wainscott DB, Nelson DL. Molecular biology of serotonin receptors. Obes Res 1995; 3 (Suppl): 441S-447S.
26. Li Q, Brownfield MS, Battaglia G, Cabrera TM, Levy AD, Rittenhouse PA, Van de Kar LD. Long-term treatment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212) and (+ -)-1-(2, 5-dimethoxy-4-iodophenyl)-2-aminopropane HC1 (DOI). J Pharmacol Exp Ther 1993; 266: 836-844.
27. Jorgensen H, Knigge U, Warberg J. Involvement of 5-HT1, 5-HT2, and 5-HT3 receptors in the mediation of the prolactin response to serotonin and 5-hydroxytryptophan. Neuroendocrinology 1992; 55: 336-343.
28. Rittenhouse PA, Bakkum EA, Levy AD, Li Q, Carnes M, Van de Kar LD. Evidence that ACTH secretion is regulated by serotonin2A/2C (5-HT2A/2C) receptors. J Pharmacol Exp Ther 1994; 271: 1647-1655.
29. Fenger M. alpha-Melanocyte-stimulating-hormone precursors in the pig pituitary. Biochem J 1986; 235: 715-722.
30. Morgan WM, Greenwood FC. Preparation of iodine-131 labeled human growth hormone high specific activity. Nature 1962; 194: 495-495.
31. Peroutka SJ, Howell TA. The molecular evolution of G protein-coupled receptors: focus on 5-hydroxytryptamine receptors. Neuropharmacology 1994; 33: 319-324.
32. Kilpatrick GJ, Bunce KT, Tyers MB. 5-HT3 receptors. Med Res Rev 1990; 10: 441-475.
33. B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol Pharmacol 1993; 43: 313-319.
34. Monsma FJ Jr, Shen Y, Ward RP, Hamblin MW, Sibley DR. Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol Pharmacol 1993; 43: 320-327.
35. Shen Y, Monsma FJ Jr., Metcalf MA, Jose PA, Hamblin MW, Sibley DR. Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. J Biol Chem 1993; 268: 18200-18204.
36. Millan MJ, Rivet JM, Canton H, Lejeune F, Bervoets K, Brocco M, Gobert A, Lefebvre de Ladonchamps B, Le Marouille Girardon S, Verriele L, Laubie M, Lavielle G. S 14671: a naphtylpiperazine 5-hydroxytryptamine 1 A agonist of exceptional potency and high efficacy possessing antagonist activity at 5-hydroxytryptamine 1C/2 receptors. J Pharmacol Exp Ther 1992; 262: 451-463.
37. Sills MA, Wolfe BB, Frazer A. Determination of selective and nonselective compounds for the 5-HT 1A and 5-HT 1B receptor subtypes in rat frontal cortex. J Pharmacol Exp Ther 1984; 231: 480-487.
38. Schechter LE, Simansky KJ. 1-(2, 5-Dimethoxy-4-iodophenyl)-2-amino-propane (DOI) exerts an anorexic action that is blocked by 5-HT2 antagonists in rats. Psychopharmacol (Berl) 1988; 94: 342-346.
39. Hoyer D. 5-hydroxytryptamine receptors and effector coupling mechanisms in peripheral tissues. In: Fozard J, ed. Peripheral Actions of 5-HT. Oxford: Oxford University Press, 1989: 72-99.
40. Gerald C, Adham N, Kao HT, Olsen MA, Laz TM, Schechter LE, Bard JA, Vaysse PJ, Hartig PR, Branchek TA, Weinshank RL. The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants. EMBO J 1995; 14: 2806-2815.
41. Glennon RA, Westkaemper RB, Bartyzel P. Medicinal chemistry of serotonergic agents. In: Peroutka SJ, ed. Serotonin Receptor Subtypes: Basic and Clinical Aspects. New-York: Wiley-Liss, 1991: 19-64.
42. Fletcher A, Forster EA, Bill DJ, Brown G, Cliffe IA, Hartley JE, Jones DE, McLenachan A, Stanhope KJ, Critchley DJ, Childs KJ, Middlefell VC, Lanfumey L, Corradetti R, Laporte AM, Gozlan H, Hamon M, Dourish CT. Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist. Behav Brain Res 1996; 73: 337-353.
43. Schreiber R, Brocco M, Audinot V, Gobert A, Veiga S, Millan MJ. (1-(2, 5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists. J Pharmacol Exp Ther 1995; 273: 101-112.
44. Ito H, Akuzawa S, Tsutsumi R, Kiso T, Kamato T, Nishida A, Yamano M, Miyata K. Comparative study of the affinities of the 5-HT3 receptor antagonists, YM060, YM114 (KAE-393), granisetron and ondansetron in rat vagus nerve and cerebral cortex. Neuropharmacology 1995; 34: 631-637.
45. Kilpatrick GJ, Jones BJ, Tyers MB. Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding. Nature 1987; 330: 746-748.