Absence of microsatellite instability in breast carcinomas with both p53 and c-erbB-2 alterations

Journal of Pathology

Volumn 187, Issue 4, 1999, Pages 424-427

  Formantici, Cristina ^a   Orlandi, Rosaria ^a   Ronchini, Chiara ^a   Pilotti, Silvana ^a   Ranzani, Guglielmina N ^b   Colnaghi, Maria I ^a   Ménard, Sylvie ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

Breast carcinoma; c erbB 2; Microsatellite instability; p53; PCR

Indexed keywords

ONCOPROTEIN; PROTEIN P53;

ADULT; ARTICLE; BREAST CARCINOMA; CANCER GENETICS; CLINICAL ARTICLE; CONTROLLED STUDY; GENE AMPLIFICATION; GENE LOCUS; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; BREAST NEOPLASMS; FEMALE; HUMANS; MICROSATELLITE REPEATS; MIDDLE AGED; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; RECEPTOR, ERBB-2; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0032980638     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199903)187:4<424::AID-PATH259>3.0.CO;2-0     Document Type: Article

References (27)

1. Sutherland GR, Richards RI. Simple tandem DNA repeats and human genetic disease. Proc Natl Acad Sci USA 1995; 92: 3636-3641.
2. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87: 159-170.
3. Aaltonen LA, Peltomäki P, Leach FS, et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260: 812.
4. Han HJ, Yanagisawa A, Kato Y, Park J-G, Nakamura Y. Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res 1993; 53: 5087-5089.
5. Helland A, Borresen-Dale AL, Peltomäki P, et al. Microsatellite instability in cervical and endometrial carcinomas. Int J Cancer 1997; 70: 499-501.
6. Peltomäki P, Lothe RA, Aaltonen LA, et al. Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome. Cancer Res 1993; 53: 5853-5855.
7. Wooster R, Cleton-Jansen A-M, Collins N, et al. Instability of short tandem repeats (microsatellites) in human cancers. Nature Genet 1994; 6: 152-156.
8. Jonsson M, Johannsson O, Borg A. Infrequent occurrence of microsatellite instability in sporadic and familial breast cancer. Eur J Cancer 1995; 31A: 2330-2334.
9. Aldaz CM, Chen TP, Sahin A, Cunningham J, Bondy M. Comparative allelotype of in situ and invasive human breast cancer: high frequency of microsatellite instability in lobular breast carcinomas. Cancer Res 1995; 55: 3976-3981.
10. Toyama T, Iwase H, Yamashita H, et al. Microsatellite instability in sporadic human breast cancers. Int J Cancer 1996; 68: 447-451.
11. Shaw JA, Walsh T, Chappell SA, Carey N, Johnson K, Walker RA. Microsatellite instability in early sporadic breast cancer. Br J Cancer 1996; 73: 1393-1397.
12. Contegiacomo A, Palmirotta R, De Marchis L, et al. Microsatellite instability and pathological aspects of breast cancer. Int J Cancer 1995; 64: 264-268.
13. Paulson TG, Wright FA, Parker BA, Russack V, Wahl GM. Microsatellite instability correlates with reduced survival and poor disease prognosis in breast cancer. Cancer Res 1996; 56: 4021-4026.
14. Patel U, Grundfest-Broniatowski S, Gupta M, Banerjee S. Microsatellite instabilities at five chromosomes in primary breast tumors. Oncogene 1994; 9: 3695-3700.
15. Ménard S, Casalini P, Pilotti S, Cascinelli N, Rilke F, Colnaghi MI. No additive impact on patient survival of the double alteration of p53 and c-erbB-2 in breast carcinomas. J Natl Cancer Inst 1996; 88: 1002-1003.
16. Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 1991; 19: 403-410.
17. Ranzani GN, Luinetti O, Padovan LS, et al. p53 gene mutations and protein nuclear accumulation are early events in intestinal type gastric cancer but late events in diffuse type. Cancer Epidemiol Biomarkers Prev 1995; 4: 223-231.
18. Terrel RB, Wille AH, Cheville JC, Nystuen AM, Cohen MB, Sheffield VC. Microsatellite instability in adenocarcinoma of the prostate. Am J Pathol 1995; 147: 799-805.
19. Smit EF, Groen HJM, Splinter TAW, Ebels T, Postmus PE. New prognostic factors in resectable non-small cell lung cancer. Thorax 1996; 51: 638-646.
20. Lin J-T, Wu M-S, Shun C-T, Lee W-J, Cheu J-C, Wang T-H. Occurrence of microsatellite instability in gastric carcinoma is associated with enhanced expression of erbB-2 oncoprotein. Cancer Res 1995; 55: 1428-1430.
21. + status and p53 mutation in colorectal cancer cell lines. Oncogene 1996; 13: 2727-2730.
22. Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993; 363: 558.
23. Strickler JG, Zheng J, Shu Q, Burgart LJ, Alberts SR, Shibata D. p53 mutations and microsatellite instability in sporadic gastric cancer when guardians fail. Cancer Res 1994; 54: 4750-4755.
24. Cahill DP, Lengauer C, Yu J, et al. Mutations of mitotic checkpoint genes in human cancers. Nature 1998; 392: 300-303.
25. Jones MH, Yamakawa K, Nakamura Y. Isolation and characterization of 19 dinucleotide repeat polymorphisms. Hum Mol Genet 1992; 1: 131-133.
26. Kimpton C, Walton A, Gill P. A further tetranucleotide repeat polymorphism in the vWF gene. Hum Mol Genet 1992; 1: 287.
27. Young J, Searle SJ, Buttenshaw R, Thomas L, Ward M. An Alu VpA marker on chromosome I demonstrates that replication errors manifest at the adenoma-carcinoma transition in sporadic colorectal tumors. Gene Chromosome Cancer 1995; 12: 251-254.