Evaluation of myocardial, hepatic, and renal perfusion in a variety of clinical conditions using an intravenous ultrasound contrast agent (Optison) and second harmonic imaging

Heart

Volumn 81, Issue 6, 1999, Pages 636-641

  Hancock, J ^a   Dittrich, H ^b   Jewitt, D E ^a   Monaghan, M J ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b Molecular Biosystems Inc   (United States)

Author keywords

Contrast enhancement; Echocardiography; Optison; Ultrasound

Indexed keywords

FS 069;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; ECHOCARDIOGRAPHY; FEMALE; HEART LEFT VENTRICLE FAILURE; HEART PERFUSION; HUMAN; IMAGING SYSTEM; INTRAVASCULAR ULTRASOUND; KIDNEY DISEASE; KIDNEY PERFUSION; LIVER DISEASE; LIVER PERFUSION; MALE; PRIORITY JOURNAL; QUALITATIVE DIAGNOSIS; TISSUE PERFUSION;

EID: 0032977268     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/hrt.81.6.636     Document Type: Article

References (19)

1. Skyba DM, Camarano G, Goodman NC, et al. Hemodynamic characteristics, myocardial kinetics and microvascular rheology of FS069, a second generation echocardiographic contrast agent capable of producing myocardial opacification from a venous injection. J Am Coll Cardiol 1996;28:1292-300.
2. Mulvagh SL, Foley DA, Aeschbacher BC, et al. Second harmonic imaging of an intravenously administered echocardiographic contrast agent. Visualisation of coronary arteries and measurement of coronary blood flow. J Am Coll Cardiol 1996;27:1519-25.
3. Kaul S. New developments in ultrasound systems for contrast echocardiography. Clin Cardiol 1997;20(suppl 1):I27-30.
4. Villarraga HR, Foley DA, Aeschbacher BC, et al. Destruction of contrast microbubbles during ultrasound imaging at conventional power output. J Am Soc Echocardiogr 1997;10:783-91.
5. Frischke C, Lindner JR, Wei K, et al. Myocardial perfusion imaging in the setting of coronary artery stenosis and acute myocardial infarction using venous injection of a second generation echocardiographic contrast agent. Circulation 1997;96:959-67.
6. Colon PJ, Richards DR, Moreno CA, et al. Benefits of reducing the cardiac cycle triggering frequency of ultrasound imaging to increase myocardial opacification with FS069 during fundamental and second harmonic imaging. J Am Soc Echocardiogr 1997;10:602-7.
7. Dittrich HC, Kuvelas T, Dadd K, et al. Safety and efficacy of the ultrasound contrast agent FS069 in normal humans: results of a phase I trial [abstract]. Circulation 1995;92(suppl):1-464.
8. Meza MF, Greener Y, Aristizabal D, et al. Myocardial contrast echocardiography: safety of FS069, a new transpulmonary echocardiographic contrast agent. J Am Soc Echocardiogr 1994;7(suppl).
9. 99Tc sestamibi single photon emission computed tomography. Circulation 1996;96:785-92.
10. Leen E, McArdle CS. Ultrasound contrast agents in liver imaging. Clin Radiol 1996;51(suppl 1):35-9.
11. Jakobsen J. Echo enhancing agents in the renal tract. Clin Radiol 1996;51(suppl 1):40-3.
12. Albrecht T, Cosgrove DO, Correas JM, et al. Renal, hepatic and cardiac enhancement on Doppler and gray scale sonograms obtained with EchoGen. Acad Radiol 1996;3(suppl 2):S198-200.
13. Kono Y, Moriyasu F, Nada T, et al. Gray scale second harmonic imaging of the liver: a preliminary animal study. Ultrasound Med Biol 1997;23:719-26.
14. Cosgrove D. Ultrasound enhancement of tumours. Clin Radiol 1996;51:44-9.
15. Forsberg F, Goldberg BB, Liu JB, et al. On the feasibility of real time, in vivo harmonic imaging with proteinaceous microspheres. J Ultrasound Med 1996;15:853-60.
16. Burns PN. Harmonic imaging with ultrasound contrast agents. Clin Radiol 1996;51:50-5.
17. Wei PN, Skyba DM, Firschke C, et al. Interactions between microbubbles and ultrasound: in vitro and in vivo observations. J Am Coll Cardiol 1997;29:1081-8.
18. Camarano GP, Ismail S, Goodman C, et al. Assessment of risk area during coronary occlusion and infarct size after reperfusion can be determined with myocardial contrast echocardiography using intravenous injections of FS069, a new contrast agent. Circulation 1994;90(suppl):1-68.
19. Dittrich HC, Bales GL, Killam AL. Comparative study for the left ventricular opacification and endocardial border delineation following intravenous administration of Albunex and FS069 in the anaesthetised canine. (Summary report 1041.) San Diego: Molecular Biosystems Inc, 1994.