The heart is not necessarily empty at syncope

Aviation Space and Environmental Medicine

Volumn 70, Issue 3 I, 1999, Pages 213-219

  Davrath, Linda R ^a   Gotshall, Robert W ^a   Tucker, Alan ^a   Sadeh, Willy Z ^a   Luckasen, Gary J ^a   Downes, Thomas R ^a   Coonts, Cindy C ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Catecholamines; Echocardiography; Lower body negative pressure

Indexed keywords

ADRENALIN; NORADRENALIN;

ADULT; ARTICLE; BRADYCARDIA; ECHOCARDIOGRAPHY; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HEART VENTRICLE FUNCTION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; NORMAL HUMAN; PATHOPHYSIOLOGY; SPACE FLIGHT; SYNCOPE; VAGUS NERVE STIMULATION;

NASA DISCIPLINE CARDIOPULMONARY; NON-NASA CENTER;

ADULT; BLOOD PRESSURE; CARDIAC OUTPUT; CARDIAC VOLUME; CATECHOLAMINES; ECHOCARDIOGRAPHY; HEART; HEART RATE; HUMANS; LOWER BODY NEGATIVE PRESSURE; MALE; POSTURE; SPACE FLIGHT; STROKE VOLUME; SYNCOPE; VASCULAR RESISTANCE; VENTRICULAR FUNCTION, LEFT;

EID: 0032976708     PISSN: 00956562     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Almqvist A, Goldenberg IF, Milsteen S. Provocation of bradycardia and hypotension by isoproterenol and upright posture in patients with unexplained syncope. N Engl J Med 1989; 320(6): 346-51.
2. Blomqvist CG. Orthostatic hypotension. Hypertension 1986; 8:722-31.
3. Blomqvist CG, Stone HL. Cardiovascular adjustment to gravitational stress. In: Shepherd JT, Abboud FM, eds. Handbook of physiology; sec 2 (The cardiovascular system), vol III (Peripheral circulation and organ blood flow, pt 2). Bethesda: American Physiological Society, 1983; 1025-63.
4. Buckey JC, Lane LD, Levine BD, et al. Orthostatic intolerance after spaceflight. J Appl Physiol 1996; 81:7-18.
5. Convertino VA, Mathes KL, et al. Hemodynamic and hormonal responses to lower body negative pressure in men with varying profiles of strength and aerobic power. Eur J Appl Physiol 1993; 67:492-8.
6. Dietz NM, Halliwill JR, Spielmann JM, et al. Sympathetic withdrawal and forearm vasodilation during vasovagal syncope in humans. J Appl Physiol 1997; 82:1785-93.
7. El-Bedawi KM, Hainsworth R. Combined head-up tilt and lower body suction: a test of orthostatic tolerance. Clin Autonom Res 1994; 4:41-7.
8. Fitzpatrick AP, Banner N, Cheng A, et al. Vasovagal reactions may occur after orthotopic heart transplantation. Am Coll Cardiol 1993; 21:1132-7.
9. Frey MAB, Hoffler GW. Association of sex and age with responses to lower body negative pressure. J Appl Physiol 1988; 65:1752-6.
10. Hainsworth R, El-Bedawi KM. Orthostatic tolerance in patients with unexplained syncope. Clin Autonom Res 1994; 4:239-44.
11. Hallman H, Farnebo L, Hamberger B, Honsson G. A sensitive method for the determination of plasma catecholamines using liquid chromatography with electrical detection. Life Sci 1978; 23:1049-52.
12. Hjemdahl P. Physiological aspects on catecholamine sampling. Life Sci 1987; 41:841-4.
13. Levine BD, Buckey JC, Fritsch JM, et al. Physical fitness and cardiovascular regulation: mechanisms of orthostatic intolerance. J Appl Physiol 1991; 70:112-22.
14. Lightfoot JT, Rowe SA, Fortney SM. Occurrence of presyncope in subjects without ventricular innervation. Clin Sci 1993; 85:695-700.
15. Linde B, Hjemdahl P. Effect of tilting on adipose tissue vascular resistance and sympathetic activity in humans. Am Physiol 1982; 242:H161-7.
16. Luft UC, Myrhe LG, Leopsky JA, Venters MD. A study of factors affecting tolerance of gravitational stress simulated by lower body negative pressure. In: Specialized physiological studies in support of manned space flight. Albuquerque: Lovelace Foundation. Contract NAS9-14472; 1976.
17. Murray RH, Thompson LJ, Bowers JA, Albright CD. Hemodynamic effects of graded hypovolemia and vasodepressor syncope induced by lower body negative pressure. Am Heart J 1968; 76:799-811.
18. Novak V, Honos G, Schondorf R. Is the heart 'empty' at syncope. J Autonom Nerv System 1996; 60:83-92.
19. Nutter DO, Hurst VW, Murray RH. Ventricular performance during graded hypovolemia induced by lower body negative pressure. J Appl Physiol 1969; 26:23-30.
20. Nwosu EA, Rahko PS, Hanson P, Grogan EW. Hemodynamic and volumetric response of the normal left ventricle to upright tilt testing. Am Heart J 1994; 128:106-13.
21. Oberg B, Thoren P. Increased activity in left ventricular receptors during hemorrhage or occlusion of caval veins in the cat-A possible cause of the vaso-vagal reaction. Acta Physiol Scand 1972; 85:164-73.
22. Parati G, Casadei R, Groppelli A, et al. Comparison of finger and intra-arterial blood pressure monitoring at rest and during laboratory testing. Hypertension 1989; 13:647-55.
23. Rowell LB, Blackmon JR. Hypotension induced by central hypovolaemia and hypoxaemia. Clin Physiol 1989; 269-77.
24. Rowell LB, Seals DR. Sympathetic activity during graded central hypovolemia in hypoxemic humans. Am J Physiol 1990; 259: H1197-206.
25. Sanders JS, Ferguson DW. Profound sympathoinhibition complicating hypovolemia in humans. Ann Intern Med 1989; 111: 439-41.
26. Sander-Jensen K, Marving J, Secher NH, et al. Does the decrease in heart rate prevent a detrimental decrease of the end systolic volume during central hypovolemia in man. Vase Dis 1990; 687-95.
27. Sander-Jensen K, Mehlsen J, Secher NH, et al. Progressive central hypovolaemia in man resulting in a vasovagal syncope. Hemodynamic and endocrine variables during venous tourniquets of the thighs. Clin Physiol 1987; 7:231-42.
28. Sander-Jensen K, Mehlsen J, Stadeager C, et al. Increase in vagal activity during hypotensive lower-body negative pressure in humans. Am J Physiol 1988; 255:R149-56.
29. Sander-Jensen K, Secher NH, Astrup A, et al. Hypotension induced by passive head-up tilt: endocrine and circulatory mechanisms. Am J Physiol 1986; 251:R742-8.
30. Schiller NB, Shah PM, Crawford M, et al. Recommendations for the quantitation of the left ventricle by two dimensional echocardiography. J Am Soc Echocardiogr 1989; 2:358-67.
31. Shalev, Y, Gal R, Tchou PJ, et al. Echocardiographic demonstration of decreased left ventricular dimensions and vigorous myocardial contraction during syncope induced by head-up tilt. Am Coll Cardiol 1991; 18:746-51.
32. Smith M. Mechanisms of vasovagal syncope: relevance to postflight orthostatic intolerance. Clin Pharmacol 1994; 34:460-5.
33. Sra J, Murthy V, Natale A, et al. Circulatory and catecholamine changes during head-up tilt testing in neurocardiogenic (vasovagal) syncope. Am Cardiol 1994; 73:33-7.
34. Sulzman FM. Life sciences space mission: overview. J Appl Physiol 1996; 81:3-6.
35. Thoren P. Vagal depressor reflexes elicited by left ventricular c-fibers during myocardial ischemia in cats. In: Schwartz PJ, Brown AM, Malliani A, Zanchetti A, ed. Neural mechanisms in cardiac arrhythmias. New York: Raven Press, 1978.
36. Thoren P. Role of cardiac vagal C-fibers in cardiovascular control. Physiol Biochem Pharmacol 1979; 86:1-94.
37. Wallin BG, Sundlof G. Sympathetic outflow to muscles during vasovagal syncope. J Auton Nerv Syst 1982; 6:287-91.
38. Yamanouchi Y, Jaalouk S, Shehadeh AA,et al. Changes in left ventricular volume during head-up tilt in patients with vasovagal syncope: an echocardiographic study. Am Heart J 1996; 131:73-80.