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Volumn 23, Issue 5, 1999, Pages 451-457

Immune reconstitution after bone marrow transplantation for combined immunodeficiencies: Down-modulation of Bcl-2 and high expression of CD95/Fas account for increased susceptibility to spontaneous and activation-induced lymphocyte cell death

Author keywords

Apoptosis; Bcl 2; Bone marrow transplant; Fas; Severe combined immunodeficiency

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; FAS ANTIGEN; PROTEIN BCL 2;

EID: 0032976288     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701608     Document Type: Article
Times cited : (27)

References (34)
  • 1
    • 0025182977 scopus 로고
    • European experience of bone marrow transplantation for SCID
    • Fischer A, Landais P, Freidrich W et al. European experience of bone marrow transplantation for SCID. Lancet 1990; 336: 850-854.
    • (1990) Lancet , vol.336 , pp. 850-854
    • Fischer, A.1    Landais, P.2    Freidrich, W.3
  • 2
    • 0028078755 scopus 로고
    • Bone marrow transplantation (BMT) in Europe for primary immunodeficiencies other than severe combined immunodeficiencies: A report from the European Group for BMT and the European Group for immunodeficiencies
    • Fischer A, Landais P, Freidrich W et al. Bone marrow transplantation (BMT) in Europe for primary immunodeficiencies other than severe combined immunodeficiencies: a report from the European Group for BMT and the European Group for immunodeficiencies. Blood 1994; 83: 1149-1155.
    • (1994) Blood , vol.83 , pp. 1149-1155
    • Fischer, A.1    Landais, P.2    Freidrich, W.3
  • 3
    • 0028902740 scopus 로고
    • Apoptosis parallels lymphopoiesis in bone marrow transplantation and HIV disease
    • Donnenberg AD, Margolick JB, Beltz LA et al. Apoptosis parallels lymphopoiesis in bone marrow transplantation and HIV disease. Res Immunol 1995; 146: 11-21.
    • (1995) Res Immunol , vol.146 , pp. 11-21
    • Donnenberg, A.D.1    Margolick, J.B.2    Beltz, L.A.3
  • 4
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the BCL2 family and cell death
    • Yang E, Korsmeyer SJ. Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 1996; 88: 386-401.
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsmeyer, S.J.2
  • 5
    • 0029609086 scopus 로고    scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser A, Harris AW, Huang DCS et al. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J 1996; 14: 6136-6147.
    • (1996) EMBO J , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.S.3
  • 6
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
    • Van Parijs L, Ibramighov A, Abbas AK. The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 1996; 4: 321-328.
    • (1996) Immunity , vol.4 , pp. 321-328
    • Van Parijs, L.1    Ibramighov, A.2    Abbas, A.K.3
  • 7
    • 0030175603 scopus 로고    scopus 로고
    • Role of Fas-mediated cell death in the regulation of immune responses
    • Van Parijs L, Abbas AK. Role of Fas-mediated cell death in the regulation of immune responses. Curr Opin Immunol 1996; 8: 355-361.
    • (1996) Curr Opin Immunol , vol.8 , pp. 355-361
    • Van Parijs, L.1    Abbas, A.K.2
  • 8
    • 0026497684 scopus 로고
    • Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood
    • Miyawaki T, Uehara T, Nibu R et al. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol 1992; 149: 3753-3758.
    • (1992) J Immunol , vol.149 , pp. 3753-3758
    • Miyawaki, T.1    Uehara, T.2    Nibu, R.3
  • 9
    • 0026482756 scopus 로고
    • Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens
    • Dhein J, Daniel PT, Trauth BC et al. Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens. J Immunol 1992; 149: 3166-3173.
    • (1992) J Immunol , vol.149 , pp. 3166-3173
    • Dhein, J.1    Daniel, P.T.2    Trauth, B.C.3
  • 10
    • 0028097822 scopus 로고
    • Purification and characterization of the Fas-ligand that induces apoptosis
    • Suda T, Nagata S. Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med 1994; 179: 873-879.
    • (1994) J Exp Med , vol.179 , pp. 873-879
    • Suda, T.1    Nagata, S.2
  • 11
    • 0026524523 scopus 로고
    • DNA fragmentation and cell death are selectively triggered in activated human lymphocytes by Fas antigen engagement
    • Owen-Schaub LB, Yonehara S, Crump III WL, Grimm EA. DNA fragmentation and cell death are selectively triggered in activated human lymphocytes by Fas antigen engagement. Cell Immunol 1992; 140: 197-205.
    • (1992) Cell Immunol , vol.140 , pp. 197-205
    • Owen-Schaub, L.B.1    Yonehara, S.2    Crump W.L. III3    Grimm, E.A.4
  • 12
    • 0027315279 scopus 로고
    • Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood t cells
    • Wesselborg S, Janssen O, Kabelitz D. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J Immunol 1993; 150: 4338-4345.
    • (1993) J Immunol , vol.150 , pp. 4338-4345
    • Wesselborg, S.1    Janssen, O.2    Kabelitz, D.3
  • 13
    • 0022841641 scopus 로고
    • T cell subpopulations defined by monoclonal antibodies after human bone marrow transplantation. II. Activation and functional subsets of the helper-inducer and cytotoxic-suppressor subpopulations defined by two colour fluorescence flow cytometry
    • Atkinson K. T cell subpopulations defined by monoclonal antibodies after human bone marrow transplantation. II. Activation and functional subsets of the helper-inducer and cytotoxic-suppressor subpopulations defined by two colour fluorescence flow cytometry. Bone Marrow Transplant 1986; 1: 121-132.
    • (1986) Bone Marrow Transplant , vol.1 , pp. 121-132
    • Atkinson, K.1
  • 14
    • 0026001221 scopus 로고
    • The reappearance of 10 differentiation antigens on peripheral blood lymphocytes after allogeneic bone marrow transplantation
    • Leino L, Lilius EM, Nikoskeleainen J et al. The reappearance of 10 differentiation antigens on peripheral blood lymphocytes after allogeneic bone marrow transplantation. Bone Marrow Transplant 1991; 8: 339-344.
    • (1991) Bone Marrow Transplant , vol.8 , pp. 339-344
    • Leino, L.1    Lilius, E.M.2    Nikoskeleainen, J.3
  • 16
    • 0029163414 scopus 로고
    • T cell reconstitution after bone marrow transplantation into adult patients does not resemble T cell development in early life
    • Storek J, Witherspoon RP, Storb R. T cell reconstitution after bone marrow transplantation into adult patients does not resemble T cell development in early life. Bone Marrow Transplant 1995; 16: 413-425.
    • (1995) Bone Marrow Transplant , vol.16 , pp. 413-425
    • Storek, J.1    Witherspoon, R.P.2    Storb, R.3
  • 17
    • 0030754129 scopus 로고    scopus 로고
    • +) T-helper cells after human allogeneic bone marrow transplantation
    • +) T-helper cells after human allogeneic bone marrow transplantation. Blood 1997; 90: 850-857.
    • (1997) Blood , vol.90 , pp. 850-857
    • Heitger, A.1    Neu, N.2    Kern, A.3
  • 18
    • 0024398224 scopus 로고
    • Cytokine activity after human bone marrow transplantation. III. Defect in IL-2 production by peripheral blood mononuclear cells is not corrected by stimulation with ca++ ionophor plus phorbol ester
    • Cooley MA, McLachan K, Atkinson K. Cytokine activity after human bone marrow transplantation. III. Defect in IL-2 production by peripheral blood mononuclear cells is not corrected by stimulation with Ca++ ionophor plus phorbol ester. Br J Haematol 1989; 73: 341-347.
    • (1989) Br J Haematol , vol.73 , pp. 341-347
    • Cooley, M.A.1    McLachan, K.2    Atkinson, K.3
  • 19
    • 0031058173 scopus 로고    scopus 로고
    • In vitro T cell depletion using Campath 1M for mismatched BMT for severe combined immunodeficiency (SCID)
    • Dickinson AM, Reid MM, Abinum M et al. In vitro T cell depletion using Campath 1M for mismatched BMT for severe combined immunodeficiency (SCID). Bone Marrow Transplant 1997; 19: 323-329.
    • (1997) Bone Marrow Transplant , vol.19 , pp. 323-329
    • Dickinson, A.M.1    Reid, M.M.2    Abinum, M.3
  • 20
    • 0032211206 scopus 로고    scopus 로고
    • + T cells after bone marrow transplantation from unrelated donors for combined immunodeficiency
    • + T cells after bone marrow transplantation from unrelated donors for combined immunodeficiency. Blood 1998; 92: 3484-3485.
    • (1998) Blood , vol.92 , pp. 3484-3485
    • Brugnoni, D.1    Airò, P.2    Malagoli, A.3
  • 21
    • 85069259144 scopus 로고    scopus 로고
    • Relevance of donor source on the T cell regeneration after bone marrow transplantation for severe combined immunodeficiency
    • in press
    • Airò P, Brugnoni D, Malagoli A et al. Relevance of donor source on the T cell regeneration after bone marrow transplantation for severe combined immunodeficiency. Haematologica 1999 (in press).
    • (1999) Haematologica
    • Airò, P.1    Brugnoni, D.2    Malagoli, A.3
  • 22
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC et al. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Meth 1991; 139: 271-279.
    • (1991) J Immunol Meth , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3
  • 23
    • 0030952229 scopus 로고    scopus 로고
    • Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: A molecular and immunological analysis
    • Bettinardi A, Brugnoni D, Quiròs-Roldan E et al. Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis. Blood 1997; 89: 902-909.
    • (1997) Blood , vol.89 , pp. 902-909
    • Bettinardi, A.1    Brugnoni, D.2    Quiròs-Roldan, E.3
  • 24
    • 0024672318 scopus 로고
    • Model system evaluating fluorescein-labeled microbeads as internal standards to calibrate fluorescence intensity of flow cytometers
    • Vogt RF, Cross GD, Henderson LO, Phillips DL. Model system evaluating fluorescein-labeled microbeads as internal standards to calibrate fluorescence intensity of flow cytometers. Cytometry 1989; 10: 294-301.
    • (1989) Cytometry , vol.10 , pp. 294-301
    • Vogt, R.F.1    Cross, G.D.2    Henderson, L.O.3    Phillips, D.L.4
  • 25
    • 18244411938 scopus 로고    scopus 로고
    • Long-term immune reconstitution and outcome after HLA-nonidentical T cell-depleted bone marrow transplantation for severe combined immunodeficiency: A European retrospective study of 116 patients
    • Haddad E, Landais P, Friedreich W et al. Long-term immune reconstitution and outcome after HLA-nonidentical T cell-depleted bone marrow transplantation for severe combined immunodeficiency: a European retrospective study of 116 patients. Blood 1998; 91: 3646-3653.
    • (1998) Blood , vol.91 , pp. 3646-3653
    • Haddad, E.1    Landais, P.2    Friedreich, W.3
  • 26
    • 0019956303 scopus 로고
    • T cell subpopulations identified by monoclonal antibodies after human bone marrow transplantation. I. Helper-inducer and cytotoxic-suppressor subsets
    • Atkinson K, Hansen JA, Storb R et al. T cell subpopulations identified by monoclonal antibodies after human bone marrow transplantation. I. Helper-inducer and cytotoxic-suppressor subsets. Blood 1982; 59: 1292-1297.
    • (1982) Blood , vol.59 , pp. 1292-1297
    • Atkinson, K.1    Hansen, J.A.2    Storb, R.3
  • 27
    • 10144249600 scopus 로고    scopus 로고
    • Reconstitution of the immune system after unrelated or partially matched T cell-depleted bone marrow transplantation in children: Immunophenotyping analysis and factors affecting the speed of recovery
    • Kook H, Goldman F, Padley D et al. Reconstitution of the immune system after unrelated or partially matched T cell-depleted bone marrow transplantation in children: immunophenotyping analysis and factors affecting the speed of recovery. Blood 1996; 88: 1089-1097.
    • (1996) Blood , vol.88 , pp. 1089-1097
    • Kook, H.1    Goldman, F.2    Padley, D.3
  • 28
    • 0029796867 scopus 로고    scopus 로고
    • Defective activation of mitogen-activated protein kinase after allogeneic bone marrow transplantation
    • Pignata C, Sanghera JS, Soiffier RJ et al. Defective activation of mitogen-activated protein kinase after allogeneic bone marrow transplantation. Blood 1996; 88: 2334-2341.
    • (1996) Blood , vol.88 , pp. 2334-2341
    • Pignata, C.1    Sanghera, J.S.2    Soiffier, R.J.3
  • 29
    • 0031909328 scopus 로고    scopus 로고
    • + T cell memory, CD45r subsets and the persistence of antigen - A unifying concept
    • + T cell memory, CD45R subsets and the persistence of antigen - a unifying concept. Immunol Today 1998; 19: 60-64.
    • (1998) Immunol Today , vol.19 , pp. 60-64
    • Bell, E.B.1    Sparshott, S.M.2    Bunce, C.3
  • 30
    • 0027488659 scopus 로고
    • T cell regeneration after bone marrow transplantation: Differential CD45 isoform expression on thymic-derived vs thymic-independent progeny
    • Mackall CL, Granger L, Sheard MA et al. T cell regeneration after bone marrow transplantation: differential CD45 isoform expression on thymic-derived vs thymic-independent progeny. Blood 1993; 82: 2585-2594.
    • (1993) Blood , vol.82 , pp. 2585-2594
    • Mackall, C.L.1    Granger, L.2    Sheard, M.A.3
  • 31
    • 0030913588 scopus 로고    scopus 로고
    • T cell regeneration: All repertoires are not created equal
    • Mackall CL, Hakim FT, Gress RE. T cell regeneration: all repertoires are not created equal. Immunol Today 1997; 18: 245-251.
    • (1997) Immunol Today , vol.18 , pp. 245-251
    • Mackall, C.L.1    Hakim, F.T.2    Gress, R.E.3
  • 32
    • 0028299065 scopus 로고
    • The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis
    • Salmon M, Pilling D, Borthwick NJ et al. The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis. Eur J Immunol 1994; 24: 892-899.
    • (1994) Eur J Immunol , vol.24 , pp. 892-899
    • Salmon, M.1    Pilling, D.2    Borthwick, N.J.3
  • 33
    • 0029922179 scopus 로고    scopus 로고
    • Analysis of T cell repopulation after allogeneic bone marrow transplantation: Significant differences between recipients of T cell-depleted and unmanipulated grafts
    • Roux E, Helg C, Dumont-Girard F et al. Analysis of T cell repopulation after allogeneic bone marrow transplantation: significant differences between recipients of T cell-depleted and unmanipulated grafts. Blood 1996; 87: 3984-3992.
    • (1996) Blood , vol.87 , pp. 3984-3992
    • Roux, E.1    Helg, C.2    Dumont-Girard, F.3
  • 34
    • 0029827501 scopus 로고    scopus 로고
    • Immunological reconstitution after bone marrow transplantation
    • Porta F, Mazzolari E, Lanfranchi A et al. Immunological reconstitution after bone marrow transplantation. Bone Marrow Transplant 1996; 18 (Suppl. 2): 148-150.
    • (1996) Bone Marrow Transplant , vol.18 , Issue.SUPPL. 2 , pp. 148-150
    • Porta, F.1    Mazzolari, E.2    Lanfranchi, A.3


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