Skin disposition of drugs after topical application in hairless rats

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 6, 1999, Pages 749-754

  Yanagimoto, Go ^a   Hayashi, Teruaki ^a   Hasegawa, Tetsuya ^a   Seki, Toshinobu ^a   Juni, Kazuhiko ^a   Sugibayashi, Kenji ^a   Morimoto, Yasunori ^a  

^a JOSAI UNIVERSITY   (Japan)

Author keywords

In situ experiment; Percutaneous absorption; Pharmacokinetics; Rat; Skin disposition; Topical application

Indexed keywords

ESTRADIOL; FLURBIPROFEN; GLYCERYL TRINITRATE; LIDOCAINE; NONSTEROID ANTIINFLAMMATORY AGENT; PHENAZONE; PIROXICAM; SCOPOLAMINE;

ARTICLE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG PENETRATION; DRUG SOLUBILITY; INTRAVENOUS DRUG ADMINISTRATION; LIPOPHILICITY; NONHUMAN; NUDE MOUSE; PHYSICAL CHEMISTRY; RAT; SKIN PERMEABILITY; TOPICAL DRUG ADMINISTRATION; TOPICAL TREATMENT; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0032975328     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.749     Document Type: Article

References (15)

1. Guy R. H., Hadgraft J., "Percutaneous Absorption," ed. by Bronaugh L., Maibach H. I., Marcel Dekker, Inc., New York, 1985, pp. 3-15.
2. Singh P., Roberts M.S., J. Pharm. Sci., 82, 127-131 (1993).
3. Guy R. H., Maibach H. I., J. Pharm. Sci., 72, 1375-1380 (1983).
4. McNeill S. C., Potts R. O., Francoeur M. L., Pharm. Res., 9, 1422-1427 (1992).
5. Krueger G. G., Wojciechowski Z. J., Burton S. A., Gilhar A., Huether S. E., Leonard L. G., Rohr U. D., Petelenz T. J., Higuchi W. I., Pershing L. K., Fundam. Appl. Toxicol., 5, S112-S121 (1985).
6. Singh P., Roberts M. S., J. Pharmacol. Exp. Ther., 268, 144-151 (1994).
7. Riviere J. E., Bowman K. F., Monteiro-Riviere N. A., Dix L. P., Carver M. P., Fundam. Appl. Toxicol., 7, 444-453 (1986).
8. Okumura M., Sugibayashi K., Ogawa K., Morimoto Y., Chem. Pharm. Bull., 37, 1404-1406 (1989).
9. Yanagimoto G., Hayashi T., Seki T., Juni K., Sugibayashi K., Morimoto Y., Pharm. Pharmacol. Commun., 4, 261-265 (1998).
10. Sugibayashi K., Yanagimoto G., Hayashi T., Seki T., Juni K., Morimoto Y., J. Control. Release, (1999) in press.
11. Yagi S., Nakayama K., Kurosaki Y., Higaki K., Kimura T., Biol. Pharm. Bull., 21, 1195-1201 (1998).
12. Auclair F., Besnard M., Dupont C., Wepierre J., Skin Pharmcol., 4, 1-8 (1991).
13. Potts R. O., Guy R. H., Pharm. Res., 9, 663-669 (1992).
14. Hatanaka T., Inuma M., Sugibayashi K., Morimoto Y., Chem. Pharm. Bull., 38, 3452-3459 (1990).
15. Singh P., Roberts M. S., J. Pharmacol. Exp. Ther., 279, 908-917 (1996).