Different frequencies of p53 codon-249 hot-spot mutations in hepatocellular carcinomas in Jiang-su province of China

International Journal of Cancer

Volumn 82, Issue 2, 1999, Pages 187-190

  Shimizu, Yasuhito ^a   Zhu, Ji Jiang ^a   Han, Fang ^b   Ishikawa, Takatoshi ^a   Oda, Hideaki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Nanton Cancer Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1;

ADULT; AGED; ARTICLE; CHEMICAL CARCINOGENESIS; CHINA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOOD CONTAMINATION; GENE MUTATION; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MALE; MUTATION RATE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADULT; AFLATOXIN B1; AGED; CARCINOMA, HEPATOCELLULAR; CHINA; CLUSTER ANALYSIS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; FOOD CONTAMINATION; GENES, P53; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MUTATION; RETROSPECTIVE STUDIES;

EID: 0032975123     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990719)82:2<187::AID-IJC6>3.0.CO;2-1     Document Type: Article

References (26)

1. AGUILAR, F., HUSSAIN, S.P. and CERUTTI, P., Aflatoxin B1 induces the transversion of G to T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc. nat. Acad. Sci. (Wash.), 90, 8586-8590 (1993).
2. ARMSTRONG, B., The epidemiology of cancer in the People's Republic of China. Int. J. Epidemiol., 9, 305-315 (1980).
3. BRASH, D.E., RUDOLPH, J.A., SIMON, J.A., LIN, A., MCKENNA, G.J., BADEN, H.P., HALPERIN, A.J. and PONTEN, J., A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc. nat. Acad. Sci. (Wash.), 88, 10124-10128 (1991).
4. BRESSAC, B., KEW, M., WANDS, J. and OZTURK, M., Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature (Lond.), 350, 429-431 (1991).
5. CAMPBELL, T.C., CHEN, J., LIU, C., LI, J. and PARPIA, B., Nonassociation of aflatoxin with primary liver cancer in a cross-sectional ecological survey in the People's Republic of China. Cancer Res., 50, 6882-6893 (1990).
6. CHALLEN, C., LUNAC, J., WARREN, W., COLLIER, J. and BASSENDINE, M.F., Analysis of the p53 tumor-suppressor gene in hepatocellular carcinomas from Britain. Hepatology, 16, 1362-1366 (1992).
7. COURSAGET, P., DEPRIL, N., CHABAUD, M., NANDI, R., MAYELO, V., LECANN, P. and YVONNET, B., High prevalence of mutations at codon 249 of the p53 gene in hepatocellular carcinomas from Senegal. Brit. J. Cancer, 67, 1395-1397 (1993).
8. FUJIMOTO, Y., HAMPTON, L.L., LUO, L.D., WIRTH, P.J. and THORGEIRSSON, S.S., Low frequency of p53 gene mutation in tumors induced by aflatoxin B1 in nonhuman primates. Cancer Res., 52, 1044-1046 (1992).
9. FUJIMOTO, Y., HAMPTON, L.L., WIRTH, P.J., WANG, N.J., XIE, J.P. and THORGEIRSSON, S.S., Alterations of tumor suppressor genes and allelic losses in human hepatocellular carcinomas in China. Cancer Res., 54, 281-285 (1994).
10. HOLLSTEIN, M., SIDRANSKY, D., VOGELSTEIN, B. and HARRIS, C.C., p53 mutations in human cancers. Science, 253, 49-53 (1991).
11. HOLLSTEIN, M.S., WILD, C.P., BLEICHER, F., CHUTIMATAEWIN, S., HARRIS, C.C., STRIVATANAKUL, P. and MONTESANO, R., p53 mutations and aflatoxin b1 exposure in hepatocellular-carcinoma patients from Thailand. Int. J. Cancer, 53, 51-55 (1993).
12. HSIEH, D.P.H. and ATKINSON, D.N., Recent aflatoxin exposure and mutation at codon 249 of the human p53 gene: lack of association. Food Addit. Contam., 12, 421-428 (1995).
13. HSU, I.C., METCALF, R.A., SUN, T., WELSH, J.A., WANG, N.G. and HARRIS, C.C., Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature (Lond. ), 350, 427-428 (1991).
14. HULLA, J.E., CHEN, Z.Y. and EATON, D.L., Aflatoxin B1-induced rat hepatic hyperplastic nodules do not exhibit a site-specific mutation within the p53 gene. Cancer Res., 53, 9-11 (1993).
15. HUSSAIN, S.P. and HARRIS, C.C., Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. Cancer Res., 58, 4023-4037 (1998).
16. INTERNATIONAL AGENCY FOR RESEARCH ON CANCER. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monograph 57, 309-395 (1993).
17. KRESS, S., JAHN, U.R., BUCHMANN, A., BANNASCH, P. and SCHWARZ, M., Mutations in human hepatocellular carcinomas from Germany. Cancer Res., 52, 3220-3223 (1992).
18. MURAKAMI, Y., HAYASHI, K., HIROHASHI, S. and SEKIYA, T., Aberrations of the tumor-suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas. Cancer Res., 51, 5520-5525 (1991).
19. ODA, H., NAKATSURU, Y. and ISHIKAWA, T., A mutational hot spot in the p53 gene is associated with hepatoblastomas. Int. J. Cancer, 60, 786-790 (1995).
20. OZTURK, M. and OTHERS, p53 mutations in hepatocellular carcinoma after aflatoxin exposure. Lancet, 338, 1356-1359 (1991).
21. SHEU, J.C., HUANG, G.T., LEE, P.H., CHUNG, J.C., CHOU, H.I., LAI, M.Y., WANG, J.T., LEE, H.S., SHIN, L.N., YANG, P.M., WANG, T.H. and CHEN, D.S., Mutations of p53 gene in hepatocellular carcinoma in Taiwan. Cancer Res., 52, 6098-6100 (1992).
22. SOINI, Y. and 16 OTHERS, An aflatoxin-associated mutational hot spot at codon 249 in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico. Carcinogenesis, 17, 1007-1012 (1996).
23. TAKESHIMA, Y, SEYAMA, T., BENNETT, W.P., AKIYAMA, M., TOKUOKA, S., INAI, K., MABUCHI, K., LAND. C.E. and HARRIS, C.C., p53 mutations in lung cancers from non-smoking atomic-bomb survivors. Lancet, 342, 1520-1521 (1993).
24. TORNALETTI, S., ROZEK, D. and PFEIFER, G.P., The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer. Oncogene, 8, 2051-2057 (1993).
25. YU, S.Z., Primary prevention of hepatocellular carcinoma. J. Gastroenterol. Hepatol., 10, 674-682 (1995).
26. YU, S.Z., CHEN, Z.Q., LIU, Y.K., HUANG, Z.Y. and ZHAO, Y.F., The aflatoxins and contaminated water in the etiological study of primary liver cancer. In: S. Natori, K. Hashimoto and Y. Ueno (eds.), Mycotoxins and phycotoxins, pp. 37-44, Elsevier, Amsterdam (1989).