The Caenorhabditis elegans gene ncc-1 encodes a cdc2-related kinase required for M phase in meiotic and mitotic cell divisions, but not for S phase

Development

Volumn 126, Issue 10, 1999, Pages 2227-2239

  Boxem, Mike ^a   Srinivasan, Dayalan G ^a   Van Den Heuvel, Sander ^a  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

Author keywords

Caenorhabditis elegans; Cdc2; Cdk; Cdk5; Cell cycle; Cell division; Ncc 1; PCTAIRE

Indexed keywords

PROTEIN KINASE; RIBONUCLEOTIDE REDUCTASE; RNA;

ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIVISION; CELL NUCLEUS MEMBRANE; CHROMOSOME CONDENSATION; DNA SYNTHESIS; EMBRYO DEVELOPMENT; GENE MUTATION; LARVAL DEVELOPMENT; MEIOSIS; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZYGOTE;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; DNA REPLICATION; GENE EXPRESSION; GENES, HELMINTH; GENOME, VIRAL; GERM CELLS; HELMINTH PROTEINS; HUMANS; LARVA; MEIOSIS; MICE; MITOSIS; MOLECULAR SEQUENCE DATA; PHENOTYPE; RNA, HELMINTH;

ANIMALIA; CAENORHABDITIS ELEGANS; INVERTEBRATA; METAZOA; VERTEBRATA;

EID: 0032972624     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (73)

1. Ahnn, J. and Fire, A. (1994). A screen for genetic loci required for body-wall muscle development during embryogenesis in Caenorhabditis elegans. Genetics 137, 483-498.
2. Ajiro, K., Yasuda, H. and Tsuji, H. (1996). Vanadate triggers the transition from chromosome condensation to decondensation in a mitotic mutant (tsTM13) inactivation of p34cdc2/H1 kinase and dephosphorylation of mitosis-specific histone H3. Eur. J. Biochem. 241, 923-930.
3. Austin, J. and Kimble, J. (1987). glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell 51, 589-599.
4. Brenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94.
5. Chae, T., Kwon, Y. T., Bronson, R., Dikkes, P., Li, E. and Tsai, L. H. (1997). Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron 18, 29-42.
6. De Bondt, H. L., Rosenblatt, J., Jancarik, J., Jones, H. D., Morgan, D. O. and Kim, S. H. (1993). Crystal structure of cyclin-dependent kinase 2. Nature 363, 595-602.
7. Draetta, G. and Beach, D. (1988). Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement. Cell 54, 17-26.
8. Edgley, M. L., Baillie, D. L., Riddle, D. L. and Rose, A. M. (1995). Genetic balancers. In Methods Cell Biol, vol. 48 (ed. H. F. Epstein and D. C. Shakes), pp. 147-184. San Diego: Academic Press.
9. Fang, F. and Newport, J. W. (1991). Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes. Cell 66, 731-742.
10. Fernandez-Sarabia, M. J. and Fantes, P. A. (1990). Ribonucleotide reductase and its regulation during the cell cycle. Trends Genet 6, 275-276.
11. Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E. and Mello, C. C. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.
12. Forsburg, S. L. and Nurse, P. (1991). Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Annu. Rev. Cell Biol. 7, 227-256.
13. Francis, R., Barton, M. K., Kimble, J. and Schedl, T. (1995). gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans. Genetics 139, 579-606.
14. Gilmore, E. C., Ohshima, T., Goffinet, A. M., Kulkarni, A. B. and Herrup, K. (1998). Cyclin-dependent kinase 5-deficient mice demonstrate novel developmental arrest in cerebral cortex. J. Neurosci. 18, 6370-6377.
15. Girard, F., Strausfeld, U., Fernandez, A. and Lamb, N. J. (1991). Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67, 1169-1179.
16. Graham, P. L. and Kimble, J. (1993). The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans. Genetics 133, 919-931.
17. Guo, S. and Kemphues, K. J. (1996). A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans. Nature 382, 455-458.
18. Harlow, E. and Lane, D. (1988). Antibodies, A Laboratory Manual. New York: Cold Spring Harbor Laboratory Press.
19. Hayashi, S. (1996). A Cdc2 dependent checkpoint maintains diploidy in Drosophila. Development 122, 1051-1058.
20. Hedgecock, E. M. and White, J. G. (1985). Polyploid tissues in the nematode Caenorhabditis elegans. Dev. Biol. 107, 128-133.
21. Hendzel, M. J., Wei, Y., Mancini, M. A., Van Hooser, A., Ranalli, T., Brinkley, B. R., Bazett-Jones, D. P. and Allis, C. D. (1997). Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma 106, 348-360.
22. Hirose, T., Tamaru, T., Okumura, N., Nagai, K. and Okada, M. (1997). PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons. Eur. J. Biochem. 249, 481-488.
23. Hocevar, B. A., Burns, D. J. and Fields, A. P. (1993). Identification of protein kinase C (PKC) phosphorylation sites on human lamin B. Potential role of PKC in nuclear lamina structural dynamics. J. Biol. Chem. 268, 7545-7552.
24. Hong, Y., Roy, R. and Ambros, V. (1998). Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans. Development 125, 3585-3597.
25. Hunter, C. P. and Wood, W. B. (1990). The tra-1 gene determines sexual phenotype cell-autonomously in C. elegans. Cell 63, 1193-1204.
26. Jeffrey, P. D., Russo, A. A., Polyak, K., Gibbs, E., Hurwitz, J., Massague, J. and Pavletich, N. P. (1995). Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376, 313-320.
27. Kadyk, L. C. and Kimble, J. (1998). Genetic regulation of entry into meiosis in Caenorhabditis elegans. Development 125, 1803-1813.
28. Kimble, J. and Simpson, P. (1997). The LIN-12/Notch signaling pathway and its regulation. Annu. Rev. Cell Dev. Biol. 13, 333-361.
29. Kimble, J. E. and White, J. G. (1981). On the control of germ cell development in Caenorhabditis elegans. Dev. Biol. 81, 208-219.
30. Kirby, C., Kusch, M. and Kemphues, K. (1990). Mutations in the par genes of Caenorhabditis elegans affect cytoplasmic reorganization during the first cell cycle. Dev. Biol. 142, 203-215.
31. Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Ashford, V. A., Xuong, N. H., Taylor, S. S. and Sowadski, J. M. (1991). Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253, 407-414.
32. Le Bouffant, F., Capdevielle, J., Guillemot, J. C. and Sladeczek, F. (1998). Characterization of brain PCTAIRE-I kinase immunoreactivity and its interactions with p11 and 14-3-3 proteins. Eur. J. Biochem. 257, 112-120.
33. Lehner, C. F. and O'Farrell, P. H. (1990). Drosophila cdc2 homologs: a functional homolog is coexpressed with a cognate variant. EMBO J. 9, 3573-3581.
34. Lieb, J. D., Albrecht, M. R., Chuang, P. T. and Meyer, B. J. (1998). MIX-1: an essential component of the C. elegans mitotic machinery executes X chromosome dosage compensation. Cell 92, 265-277.
35. Massague, J. (1998). TGF-beta signal transduction. Annu. Rev. Biochem. 67, 753-791.
36. Masui, Y. and Markert, C. L. (1971). Cytoplasmic control of nuclear behavior during meiotic maturalion of frog oocytes. J. Exp. Zool. 177, 129-145.
37. Matsushime, H., Quelle, D. E., Shurtleff, S. A., Shibuya, M., Sherr, C. J. and Kato, J. Y. (1994). D-type cyclin-dependent kinase activity in mammalian cells. Mol. Cell. Biol. 14, 2066-2076.
38. Matsushime, H., Roussel, M. F., Ashmun, R. A. and Sherr, C. J. (1991). Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 65, 701-713.
39. McCarter, J., Bartlett, B., Dang, T. and Schedl, T. (1999). On the control of oocyte meiotic maturation and ovulation in Caenorhabditis elegans. Dev. Biol. 205, 111-128.
40. Meyerson, M., Enders, G. H., Wu, C. L., Su, L. K., Gorka, C., Nelson, C., Harlow, E. and Tsai, L. H. (1992). A family of human cdc2-related protein kinases. EMBO J. 11, 2909-2917.
41. Mori, H., Palmer, R. E. and Sternberg, P. W. (1994). The identification of a Caenorhabditis elegans homolog of p34cdc2 kinase. Mol. Gen. Genet. 245, 781-786.
42. Nigg, E. A. (1995). Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. BioEssays 17, 471-480.
43. Nikolic, M., Dudek, H., Kwon, Y. T., Ramos, Y. F. and Tsai, L. H. (1996). The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev. 10, 816-825.
44. Nonet, M. L., Staunton, J. E., Kilgard, M. P., Fergestad, T., Hartwieg, E., Horvitz, H. R., Jorgensen, E. M. and Meyer, B. J. (1997). Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles. J. Neurosci. 17, 8061-8073.
45. Norbury, C. and Nurse, P. (1992). Animal cell cycles and their control. Annu. Rev. Biochem. 61, 441-470.
46. Ohtsubo, M. and Roberts, J. M. (1993). Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science 259, 1908-1912.
47. Pagano, M., Pepperkok, R., Lukas, J., Baldin, V., Ansorge, W., Bartek, J. and Draetta, G. (1993). Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts. J. Cell Biol. 121, 101-111.
48. Peter, M., Nakagawa, J., Doree, M., Labbe, J. C. and Nigg, E. A. (1990). In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell 61, 591-602.
49. Quelle, D. E., Ashmun, R. A., Shurtleff, S. A., Kato, J. Y., Bar-Sagi, D., Roussel, M. F. and Sherr, C. J. (1993). Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev. 7, 1559-1571.
50. Riabowol, K., Draetta, G., Brizuela, L., Vandre, D. and Beach, D. (1989). The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells. Cell 57, 393-401.
51. Riddle, D. L. and Albert, P. S. (1997). Genetic and environmental regulation of dauer larva development. In C. elegans II, (ed. D. L. Riddle, T. Blumenthal, B. J. Meyer and J. R. Priess), pp. 739-768. New York: Cold Spring Harbor Laboratory Press.
52. Riddle, D. L., Blumenthal, T., Meyer, B. J. and Priess, J. R. (1997). C. elegans II. New York: Cold Spring Harbor Laboratory Press.
53. Rose, K. L., Winfrey, V. P., Hoffman, L. H., Hall, D. H., Furuta, T. and Greenstein, D. (1997). The POU gene ceh-18 promotes gonadal sheath cell differentiation and function required for meiotic maturation and ovulation in Caenorhabditis elegans. Dev. Biol. 192, 59-77.
54. Sauer, K., Weigmann, K., Sigrist, S. and Lehner, C. F. (1996). Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase. Mol. Biol. Cell 7, 1759-1769.
55. Sherr, C. J. (1994). G1 phase progression: cycling on cue. Cell 79, 551-555.
56. Sherr, C. J. (1996). Cancer cell cycles. Science 274, 1672-1677.
57. Sherr, C. J. and Roberts, J. M. (1995). Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9, 1149-1163.
58. Sigrist, S., Ried, G. and Lehner, C. F. (1995). Dmcdc2 kinase is required for both meiotic divisions during Drosophila spermatogenesis and is activated by the Twine/cdc25 phosphatase. Mech. Dev. 53, 247-260.
59. Slack, F. and Ruvkun, G. (1997). Temporal pattern formation by heterochronic genes. Annu. Rev. Genet. 31, 611-634.
60. Stern, B., Ried, G., Clegg, N. J., Grigliatti, T. A. and Lehner, C. F. (1993). Genetic analysis of the Drosophila cdc2 homolog. Development 117, 219-232.
61. Storfer-Glazer, F. A. and Wood, W. B. (1994). Effects of chromosomal deficiencies on early cleavage patterning and terminal phenotype in Caenorhabditis elegans embryos. Genetics 137, 499-508.
62. Sulston, J. E. and Horvitz, H. R. (1977). Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev. Biol. 56, 110-156.
63. Sulston, J. E. and Horvitz, H. R. (1981). Abnormal cell lineages in mutants of the nematode Caenorhabditis elegans. Dev. Biol. 82, 41-55.
64. Sulston, J. E., Schierenberg, E., White, J. G. and Thomson, J. N. (1983). The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev. Biol. 100, 64-119.
65. Tabara, H., Grishok, A. and Mello, C. C. (1998). RNAi in C. elegans: soaking in the genome sequence. Science 282, 430-431.
66. The C. elegans Sequencing Consortium. (1998). Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282, 2012-2018.
67. Th'ng, J. P., Wright, P. S., Hamaguchi, J., Lee, M. G., Norbury, C. J., Nurse, P. and Bradbury, E. M. (1990). The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product. Cell 63, 313-324.
68. Tsai, L. H., Lees, E., Faha, B., Harlow, E. and Riabowol, K. (1993a). The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene 8, 1593-1602.
69. Tsai, L. H., Takahashi, T., Caviness, V. S., Jr. and Harlow, E. (1993b). Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development 119, 1029-1040.
70. van den Heuvel, S. and Harlow, E. (1993). Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262, 2050-2054.
71. Ward, G. E. and Kirschner, M. W. (1990). Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C. Cell 61, 561-577.
72. Williams, B. D., Schrank, B., Huynh, C., Shownkeen, R. and Waterston, R. H. (1992). A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites. Genetics 131, 609-624.
73. Wood, W. B. (1988). The nematode C. elegans. New York: Cold Spring Harbor Laboratory Press.