The tachykinin NK-1 receptor antagonist, RP-67580, infused into the ventral tegmental area prevents stress-induced analgesia in the formalin test

Physiology and Behavior

Volumn 66, Issue 4, 1999, Pages 717-721

  Altier, Nadège ^a   Stewart, Jane ^a  

^a and Applied Physiology   (Canada)

Author keywords

Antinociception; Dopamine; Formalin test; Neurokinins; Stress; Substance P; Tachykinins; Tonic pain

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; FORMALDEHYDE; NEUROKININ; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; SUBSTANCE P; TACHYKININ;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; CONTROLLED STUDY; INTRACEREBRAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SHOCK; SHORT SURVEY; STRESS; VENTRAL TEGMENTUM;

EID: 0032972138     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(98)00246-7     Document Type: Article

References (43)

1. Abbott F.V., Franklin K.B.J., Connell B. The stress of a novel environment reduces formalin pain. Possible role of serotonin Eur. J. Pharmacol. 126:1986;141-144.
2. Altier N., Stewart J. Intra-VTA infusions of the substance P analogue, DiMe-C7, and intra-accumbens infusions of amphetamine induce analgesia in the formalin test for tonic pain. Brain Res. 62:1993;279-285.
3. Altier N., Stewart J. Opioid receptors in the ventral tegmental area contribute to stress-induced analgesia in the formalin test for tonic pain. Brain Res. 718:1996;203-206.
4. Altier N., Stewart J. Tachykinin NK-1 and NK-3 selective agonists induce analgesia in the formalin test for tonic pain following intra-VTA or intra-accumbens microinfusions. Behav. Brain Res. 89:1997;151-165.
5. Altier N., Stewart J. Dopamine receptor antagonists in the nucleus accumbens attenuate analgesia induced by ventral tegmental area substance P or morphine, and by nucleus accumbens amphetamine. J. Pharmacol. Exp. Ther. 285:1998;208-215.
6. Amir S., Amit Z. The pituitary gland mediates acute and chronic pain responsiveness in stressed and non-stressed rats. Life Sci. 24:1979;439-448.
7. Bannon M.J., Elliott P.J., Alpert J.E., Goedert M., Iversen S.D., Iversen L.L. Role of endogenous substance P in stress-induced activation of mesocortical dopamine neurons. Nature. 306:1983;791-792.
8. Bannon M.J., Deutch A.Y., Tam S.-Y., Zamir N., Eskay R.L., Lee J.-M., Maggio J.E., Roth R.H. Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin. Brain Res. 381:1986;393-396.
9. Beresford I.J.M., Birch P.J., Hagan R.M., Ireland S.J. Investigation into species variants in tachykinin NK-1 receptors by use of the non-peptide antagonist, CP-96,345. Br. J. Pharmacol. 104:1991;292-293.
10. Blair R., Galina Z., Holmes L.J., Amir Z. Stress-induced analgesia. A performance deficit or a change in pain responsiveness Behav. Neural. Biol. 34:1982;152-158.
11. Boix F., Huston J.P., Schwarting R.K.W. Effects of C- and N-terminal sequences of substance P on in vivo dopamine release in the neostriatum and nucleus accumbens. Brain Res. 592:1992;181-597.
12. Boix F., Mattioli R., Adams F., Huston J.P., Schwarting R.K.W. Effects of substance P on extracellular dopamine in neostriatum and nucleus accumbens. Eur. J. Pharmacol. 216:1992;103-107.
13. Cador M., Rivet J.-M., Kelley A.E., LeMoal M., Stinus L. Substance P, neurotensin and enkephalin injections into the ventral tegmental area. Comparative study on dopamine turnover in several forebrain structures Brain Res. 486:1989;357-363.
14. Cannon J.T., Lewis J.W., Weinberg V.E., Liebeskind J.C. Evidence for the independence of brainstem mechanisms mediating analgesia induced by morphine and two forms of stress. Brain Res. 269:1983;231-236.
15. Culman J., Wiegand B., Spitznagel H., Klee S., Unger T. Effects of the tachykinin NK-1 receptor antagonist, RP-67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B. Br. J. Pharmacol. 114:1995;1310-1316.
16. Deutch A.Y., Maggio J.E., Bannon M.J., Kalivas P.W., Tam S.-Y., Goldstein M., Roth R.H. Substance K and substance P differentially modulate mesolimbic and mesocortical systems. Peptides. 6:1985;113-122.
17. Deutch A.Y., Roth R.H. The determinants of stress-induced activation of the prefrontal cortical dopamine system. Prog. Brain Res. 85:1990;367-402.
18. Drugan R.C., Ader D.N., Maier S.F. Shock controllability and the nature of stress-induced analgesia. Behav. Neurosci. 99:1985;791-801.
19. Eison A.S., Eison M.S., Iversen S.D. The behavioural effects of a novel substance P analogue following infusion into the ventral tegmental area or substantia nigra of rat brain. Brain Res. 238:1982;137-152.
20. Eison A.S., Iversen S.D., Sandberg S.E.B., Watson S., Hanely M.R., Iversen L.L. A novel substance P analogue, DiMe-C7. Evidence for stability in rat brain and prolonged central actions Science. 215:1982;188-190.
21. Elliott P.J., Iversen S.D. Behavioral effects of tachykinins and related peptides. Brain Res. 381:1986;68-76.
22. Fanselow M.S. Shock-induced analgesia on the formalin test. Effects of shock severity, naloxone, hypophysectomy, and associated variables Behav. Neurosci. 98:1984;79-95.
23. Fanselow M.S., Baackes M.P. Conditioned fear-induced opiate analgesia on the formalin test. Evidence for two aversive motivational systems Learn. Motiv. 13:1982;200-221.
24. Fardin V., Foucault F., Bock M.D., Jolly A., Flamand O., Clerc F., Garret C. Variations in affinities for the NK-1 receptor. Differences between the non-peptide substance P antagonists RP-67580 and CP-96,345 and the agonist septide Regul. Pept. 46:1993;300-303.
25. Garret C., Carruette A., Fardin V., Moussaoui S., Peyronel J.-F., Blanchard J.-C., Laduron P.M. Pharmacological properties of a selective nonpeptide substance P antagonist. Proc. Natl. Acad. Sci. USA. 88:1991;10208-10212.
26. Johnson S.W., North R.A. Opioids excite dopamine neurons by hyperpolarization of local interneurons. J. Neurosci. 12:1992;483-488.
27. Kalivas P.W., Abhold R. Enkephalin release into the ventral tegmental area in response stress. Modulation of mesocorticolimbic dopamine Brain Res. 414:1987;339-348.
28. Kalivas P.W., Richardson-Carlson R. Endogenous enkephalin modulation of dopamine neurons in the ventral tegmental area. Am. J. Physiol. 258:1986;243-249.
29. Kalivas P.W., Widerlov E., Stanley D., Breese G., Prange A.J. Jr. Enkephalin action on the mesolimbic dopamine system. A dopamine-dependent and dopamine-independent increase in locomotor activity J. Pharmacol. Exp. Ther. 227:1983;229-237.
30. Kelley A.E., Stinus L., Iversen S.D. Behavioral activation induced in the rat by substance P infusion into the ventral tegmental area. Implication of dopaminergic A10 neurons Neurosci. Lett. 11:1979;335-339.
31. Latimer L.G., Duffy P., Kalivas P.W. Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area. J. Pharmacol. Exp. Ther. 241:1987;328-337.
32. Lewis J.W., Terman G.W., Watkins L.R., Mayer D.J., Liebeskind J.C. Opioid and non-opioid mechanisms of footshock-induced analgesia. Role of the spinal dorsolateral funiculus Brain Res. 267:1983;139-144.
33. Lisoprawski A., Blanc G., Glowinski J. Activation by stress of the habenulo-interpeduncular substance P neurons in the rat. Neurosci. Lett. 25:1981;47-51.
34. Manning B.H., Morgan M.J., Franklin K.B.J. Morphine analgesia in the formalin test. Evidence for forebrain and midbrain sites of action Neuroscience. 63:1994;289-295.
35. Morgan, M. J.: Opioid-dopamine interactions in analgesia in the formalin test. Doctoral Dissertation, McGill University, Montreal, Quebec, Canada; 1990.
36. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 1986;Academic Press, Orlando, FL.
37. Regoli D., Drapeau G., Dion S., Couture R. New selective agonists for neurokinin receptors. Pharmacological tools for receptor characterization Trends Pharmacol. Sci. 9:1988;290-295.
38. Snider R.M., Constantine J.W., Lowe J.A. III, Longo K.P., Lebel W.S., Woody H.A., Drozda S.E., Desdai M.C., Vinick F.J., Spencer R.W., Hess H.-J. A potent nonpeptide antagonist of the substance P (NK-1) receptor. Science. 251:1991;435-437.
39. Stinus L., Kelley A.E., Iversen S.D. Increased spontaneous activity following substance P infusion into A10 dopaminergic area. Nature. 276:1978;616-618.
40. Stoessl J.A. NK-3 tachykinin receptors localized on midbrain dopamine neurons. Soc. Neurosci. Abstr. 18:1992;454.
41. Tamiya R., Hanada M., Kawai Y., Inagaki S., Takagi H. Substance P afferents have synaptic contacts with dopaminergic neurons in the ventral tegmental area of the rat. Neurosci. Lett. 110:1990;11-15.
42. Vaccarino A.L., Marek P., Liebeskind J.C. Stress-induced analgesia prevents the development of the tonic, late phase of pain produced by subcutaneous formalin. Brain Res. 572:1992;250-252.
43. Watling K.J. Nonpeptide antagonists herald new era in tachykinin research. Trends Pharol. Sci. 13:1992;266-269.