Involvement of protein serine and threonine phosphorylation in human sperm capacitation

Biology of Reproduction

Volumn 60, Issue 6, 1999, Pages 1402-1409

  Naz, Rajesh K ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SERINE THREONINE KINASE; SERINE; THREONINE;

ARTICLE; FERTILIZATION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; SPERMATOZOON CAPACITATION; ZONA PELLUCIDA;

ANTIBODIES, MONOCLONAL; ANTIGENS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOSORBENT TECHNIQUES; MALE; MOLECULAR WEIGHT; PHOSPHORYLATION; PHOSPHOSERINE; PHOSPHOTHREONINE; SPERM CAPACITATION; SPERM-OVUM INTERACTIONS; SPERMATOZOA; ZONA PELLUCIDA;

EID: 0032971198     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod60.6.1402     Document Type: Article

References (35)

1. Fischer EH, Krebs EG. The conversion of phosphorylase b to phosphorylase a. J Biol Chem 1955; 216:121-132.
2. Pawson T. Protein modules and signalling network. Nature 1995; 373: 573-580.
3. Hunter T. Protein kinase classification. Methods Enzymol 1991; 200: 3-37.
4. Ullrich A, Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell 1990; 61:203-212.
5. Johnson, LN, Noble MEM, Owen DJ. Active and inactive protein kinases: structural basis for regulation. Cell 1996; 85:149-158.
6. Johnson LN, Barford D. The effects of phosphorylation on the structure and function of proteins. Annu Rev Biophys Biomol Struct 1993; 22:199-232.
7. Wera S, Hemmings BA. Serine/threonine protein phosphatases. Biochem J 1995; 311:17-29.
8. Yanagimachi R. Mammalian fertilization. In: Knobil E, Neill JD (eds.), The Physiology of Reproduction. New York: Raven Press; 1994: 189-318.
9. Naz RK, Ahmad K, Kumar P. Role of membrane phosphotyrosine proteins in human spermatozoal function. J Cell Sci 1991; 99:1064-1072.
10. Naz RK, Ahmad K. Molecular identities of human sperm proteins that bind human zona pellucida: nature of sperm-zona interaction, tyrosine kinase activity and involvement of FA-1. Mol Reprod Dev 1994; 39: 397-408.
11. Naz RK. Protein tyrosine phosphorylation and signal transduction during capacitation/acrosome reaction and zona pellucida binding in human sperm. Arch Androl 1996; 37:47-55.
12. Naz RK, Alexander NJ, Isahakia M, Hamilton MD. Monoclonal antibody to a human sperm membrane glycoprotein that inhibits fertilization. Science 1984; 225:342-344.
13. Naz RK, Phillips TM, Rosenblum BB. Characterization of the fertilization antigen-1 for the development of a contraceptive vaccine. Proc Natl Acad Sci USA 1986; 83:5713-5717.
14. Naz RK, Sacco A, Singh O, Pal R, Talwar GP Development of contraceptive vaccines for humans using antigens derived from gametes (spermatozoa and zona pellucida) and hormones (human chorionic gonadotropin): current status. Hum Reprod Update 1995; 1:1-18.
15. Kadam AL, Fateh M, Naz RK. Fertilization antigen (FA-1) completely blocks human sperm binding to human zona pellucida: FA-1 antigen may be sperm receptor for zona pellucida in humans. J Reprod Immunol 1995; 29:19-30.
16. Zhu X, Naz RK. Fertilization antigen-1: cDNA cloning, testis-specific expression, and immunocontraceptive effects. Proc Natl Acad Sci USA 1997; 94:4704-4709.
17. Naz RK. Involvement of fertilization antigen (FA-1) in involuntary immunoinfertility in humans. J Clin Invest 1987; 80:1375-1383.
18. Ahmad K, Naz RK. Thymosin alpha 1 and FA-1 monoclonal antibody affect fertilizing capacity of human sperm by modulating protein phosphorylation pattern. J Reprod Immunol 1995; 29:239-263.
19. Naz RK, Morte C, Ahmad K, Martinez P Hexokinase present in human sperm is not tyrosine phosphorylated but its antibodies affect fertilizing capacity. J Androl 1996; 17:143-150.
20. Naz RK. c-Abl proto-oncoprotein is expressed and tyrosine phosphorylated in human sperm cell. Mol Reprod Dev 1998; 51:210-217.
21. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-685.
22. Naz RK, Zhu X, Menge AC. Expression of tumor necrosis factor-alpha and its receptors type I and type II in human oocytes. Mol Reprod Dev 1997; 47:127-133.
23. Towbin H, Stachelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76:4350-4354.
24. Frackelton AR Jr, Ross AH, Herman NE. Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells. Mol Cell Biol 1983; 3:1343-1352.
25. Abu-Lawi KI, Sultzer BM. Induction of serine and threonine protein phosphorylation by endotoxin-associated protein in murine resident peritoneal macrophages. Infect Immun 1995; 63:498-502.
26. 2 is activated by the hepatocyte growth factor receptor-kinase in Madin Darby canine kidney cells. J Cell Sci 1997; 110:1655-1663.
27. Duncan ED, Fraser LR. Cyclic AMP-dependent phosphorylation of epididymal mouse sperm proteins during capacitation in vitro: identification of a mr 95,000 phosphotyrosine-containing protein. J Reprod Fertil 1993; 97:287-299.
28. Luconi M, Barni T, Vannelli GB, Krausz C, Marra F, Benedetti PA, Evangelista V, Francavilla S, Properzi G, Forti G, Baldi E. Extracellular signal-regulated kinases modulate capacitation of human spermatozoa. Biol Reprod 1998; 58:1476-1489.
29. Roten R, Paz GF, Hamonnai ZT, Kalina M, Naor Z. Protein kinase C is present in human sperm: possible role of flagellar motility. Proc Natl Acad Sci USA 1990; 87:7305-7308.
30. 2 serine/threonine protein kinase in human sperm cell function. Biol Reprod 1993; 48:720-728.
31. Naz RK, Ahmad K, Kaplan P. Expression and function of ras-protooncogene proteins in human sperm. J Cell Sci 1992; 102:487-494.
32. Naz RK, Ahmad K. Presence of expression products of c-erbβ-1 and cerbβ-2/HER2 genes on mammalian sperm cell, and effects of their regulation on fertilization. J Reprod Immunol 1992; 21:233-239.
33. Tesarik J, Moos J, Mendoza C. Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm. Endocrinology 1993; 133:328-335.
34. Leclerc P, de Lamirande E, Gagnon C. Cyclic adenosine 3′, 5′-monophosphate-dependent regulation of protein tyrosine phosphorylation in relation to human sperm capacitation and motility. Biol Reprod 1996; 55:684-692.
35. 1 membrane association of epidermal growth factor. Science 1990; 249:296-298.