Protein tyrosine phosphorylation and signal transduction during capacitation-acrosome reaction and zona pellucida binding in human sperm

Archives of Andrology

Volumn 37, Issue 1, 1996, Pages 47-55

  Naz, R K ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Acrosome reaction; Capacitation; Fertilization; Signal transduction; Sperm; Tyrosine kinase; Tyrosine phosphorylation

Indexed keywords

PHOSPHOPROTEIN; PROTEIN TYROSINE KINASE;

ACROSOME REACTION; ARTICLE; AUTOPHOSPHORYLATION; EXOCYTOSIS; FERTILIZATION; HUMAN; HUMAN CELL; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPERMATOZOON CAPACITATION; ZONA PELLUCIDA;

EID: 79961239544     PISSN: 01485016     EISSN: None     Source Type: Journal    
DOI: 10.3109/01485019608988501     Document Type: Article

References (48)

1. Ahmad K, Naz RK (1995): Thymosin alpha-1 and FA-1 monoclonal antibody affect fertilizing capacity of human sperm by modulating protein phosphorylation pattern. J Reprod Immunol 29:1-17.
2. Baldi E, Falsetti C, Gervasi G, Carloni V, Casano R, Forti G (1992): Stimulation of platelet aggregation factor synthesis by progesterone and A23187 in human spermatozoa. Biochem J 292:209-216.
3. r 95,000 phosphotyrosine-containing protein. J Reprod Fertil 97:287-299.
4. Fischer EH, Krebs EG (1955): The conversion of phosphorylase b to phosphorylase a. J Biol Chem 216:121-132.
5. Huganir RL, Delcour AH, Greengard P, Hess GP (1986): Phosphorylation of the nicotine acetylcholine receptor regulates its rate of desensitization. Nature 321:774-776.
6. Hussenet F, Dousset B, Cordonnier JL, Jacob C, Foliquet B, Grignon G (1993): Tumor necrosis factor alpha and interleukin-2 in normal and infected seminal plasma. Hum Reprod 8:409-411.
7. Kadam AL, Fateh M, Naz RK (1995): Fertilization antigen (FA-1) completely blocks human sperm binding to human zone pellucida: FA-1 antigen may be sperm receptor for zona pellucida in humans. J Reprod Immunol 29:19-30.
8. Kaplan P, Naz RK (1992): The fertilization antigen-1 does not have any proteolytic/acrosin activity, but its monoclonal antibody inhibits sperm capacitation and acrosome reaction. Fertil Steril 58:396-402.
9. Kopf G (1989): Mechanisms of signal transduction in mouse sperm. Ann NY Acad Sci 564:289-302.
10. Kumar G, Patel D, Naz RK (1993): c-myc mRNA is present in human sperm cells. Cell Mol Biol Res 39.111-117.
11. Lathrop WE, Carmichael EP, Myles DG, Primakoff P (1990): cDNA cloning reveals the molecular structure of a sperm surface protein, PH-20 involved in sperm-egg adhesion and the wide distribution of its gene among mammals. J Cell Biol 42:693-701.
12. Laursen I, Briand P, Lykkesfeldt AE (1990): Serum albumin as a modulator on growth of the human breast cancer cell line, MCF-7. Anticancer Res 10:343-351.
13. Leyton L, LeGuen P, Bunch D, Saling PM (1992): Regulation of mouse gamete interaction by sperm tyrosine kinase. Proc Natl Acad Sci USA 89:11692-11695.
14. Leyton L, Saling PM (1989): 95 kD sperm protein binds ZP3 and serves as tyrosine kinase substrate in response to zona binding. Cell 57:1123-1130.
15. Liu MS, Abersold R, Fann C-H, Lee C-YG (1992): Molecular and development studies of a sperm acrosome antigen recognized by HS-63 monoclonal antibody. Biol Reprod 46:937-948.
16. Naz RK, Ahmad K (1992): Presence of expression products of c-erbβ-1 and c-erbβ-2/HER2 genes on mammalian sperm cell, and effects of their regulation on fertilization. J Reprod Immunol 21:223-239.
17. Naz RK, Ahmad K (1994). Molecular identities of human sperm proteins that bind human zona pellucida: nature of sperm-zona interaction, tyrosine kinase activity and involvement of FA-1. Mol Reprod Dev 39:397-408.
18. Naz RK, Ahmad K, Kaplan P (1992): Expression and function of ras-proto-oncogene proteins in human sperm cells. J Cell Sci 102:487-494.
19. 2 serine/threonine protein kinase in human sperm cell function. Biol Reprod 48:720-728.
20. Naz RK, Ahmad K, Kumar G (1991): Presence and role of c-myc proto-oncogene product in mammalian sperm cell function. Biol Reprod 44:842-850.
21. Naz RK, Ahmad K, Kumar R (1991): Role of membrane phosphotyrosine proteins in human spermatozoal function. J Cell Sci 99:157-165.
22. Naz RK, Alexander NJ, Isahakia M, Hamilton, MD (1984): Monoclonal antibody to a human sperm membrane glycoprotein that inhibits fertilization. Science 225:342-344.
23. Naz RK, Brazil C, Overstreet JW (1992): Effects of antibodies to sperm surface fertilization antigen-1 on human sperm-human zona interaction. Fertil Steril 57:1304-1310.
24. Naz RK, Butler A, Witt BR, Barad D, Menge AC (1995): Levels of interferon-⌈ and tumor necrosis factor-α in sera and cervical mucus of fertile and infertile women: implication in infertility. J Reprod Immunol 29:105-117.
25. Naz RK, Butler A (1996): Interleukin-6 and -8 levels in sera and cervical mucus of fertile, idiopathic infertile and immunofertile and immunoinfertile women: implication in infertility. Am J Reprod Immunol 35:, in press.
26. Naz RK, Chaturvedi MM, Aggarwal BB (1994): Role of cytokines and proto-oncogenes in sperm cell function: relevance to immunologic infertility. Am J Reprod Immunol 32:26-27.
27. Naz RK, Kaplan P (1993): Effects of epidermal growth factor on human sperm cell function. J Androl 5:240-247.
28. Naz RK, Kaplan P (1994): Increased levels of interleukin-6 in seminal plasma of infertile men. J Androl 15:220-227.
29. Naz RK, Kaplan P (1994): Interleukin-6 enhances the fertilizing capacity of human sperm by increasing capacitation and acrosome reaction. J Androl 15:228-233.
30. Naz RK, Kaplan P, Goldstein AL (1992): Thymosin alpha-1 enhances the fertilizing capacity of human sperm cell: implication in diagnosis and treatment of male infertility. Biol Reprod 47:1064-1072.
31. 1 oligonucleotide synthetase in human sperm cells. J Cell Physiol 146:143-156.
32. Naz RK, Morte C, Garcia-Framis V, Kaplan P, Martinez P (1993): Characterization of a sperm-specific monoclonal antibody and isolation of a 95-kilodalton fertilization antigen-2 from human sperm. Biol Reprod 49:1236-1244.
33. Naz RK, Phillips TM, Rosenblum BB (1986): Characterization of the fertilization antigen-1 for the development of a contraceptive vaccine. Proc Natl Acad Sci USA 83:5713-5717.
34. Naz RK, Rosenblum BB, Menge AC (1984): Characterization of a membrane antigen from rabbit testes and sperm isolated by using monoclonal antibodies and effect of its antiserum on fertility. Proc Natl Acad Sci USA 81:857-861.
35. Naz RK, Sacco A, Singh O, Pal R, Talwar GP (1995): Development of contraceptive vaccines for humans using antigens derived from gametes (spermatozoa and zona pellucida) and hormones (human chorionic gonadotrophin): current status. Hum Reprod Update 1:1-18.
36. Naz RK, Sacco AG, Yurewicz EC (1991): Human spermatozoal FA-1 binds with ZP3 of porcine zona pellucida. J Reprod Immunol 20:43-58.
37. Naz RK, Stanley ER (1995): Enhanced levels of colony stimulating factor-1 (CSF-1) in sera and seminal plasma of antisperm antibody-positive infertile men. Arch Androl 35:5-11.
38. O'Rand MG (1988): Sperm-egg recognition and barriers to interspecies fertilization. Gamete Res 19:315-328.
39. Paradisi R, Capelli M, Mandini M, Bellavia E, Focacci M, Flamigni C (1995): Interleukin-2 in seminal plasma of fertile and infertile men. Arch Androl 35:35-42.
40. Pawson T (1995): Protein modules and signalling network. Nature 373:573-580.
41. Rajasekaran M, Hellstrom WJG, Naz RK, Sikka SC (1995): Oxidative stress and interleukins in seminal plasma during leukocytospermia. Fertil Steril 64:166-171.
42. Roten R, Paz GF, Hamonnai ZT, Kalina M, Naor Z (1990): Protein kinase C is present in human sperm: possible role of flagellar motility. Proc Natl Acad Sci USA 87:7305-7308.
43. Shimoya K, Matsuzaki N, Tsutsui T, Taniguchi T, Saji F, Tanizawa O (1993): Detection of interleukin-8 (IL-8) in seminal plasma and elevated IL-8 in seminal plasma of infertile patients with leukospermia. Fertil Steril 59:885-888.
44. Smith JA, Francis SH, Corbin JD (1993): Autophosphorylation: a salient feature of protein kinases. Mol Cell Biol 127/128:51-70.
45. Tesarik J, Moos J, Mendoza C (1993): Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm. Endocrinology 133:328-335.
46. 1, membrane association by epidermal growth factor. Science 249:296-298.
47. Ullrich A, Shlessinger J (1990): Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
48. Yanagimachi R (1994): Mammalian fertilization. In: The Physiology of Reproduction, Knobil E, Neill JD, eds. New York: Raven, pp 189-318.