Persistent opacification of the left ventricle and myocardium with a new echo contrast agent

Ultrasound in Medicine and Biology

Volumn 25, Issue 5, 1999, Pages 763-769

  Strauss, Andreas L ^a   Beller, Klaus Dieter ^b  

^a Dominikus Krankenhaus Dusseldorf Heerdt   (Germany)

^b ALTANA PHARMA AG   (Germany)

Author keywords

Echo contrast agent (BY963); Myocardial contrast echocardiography; Persistent LV opacification

Indexed keywords

ACOUSTIC PROPERTIES; BLOOD; BLOOD VESSELS; CARBON; CARDIOVASCULAR SYSTEM; DENSITOMETERS; FLUORINE COMPOUNDS; LIPIDS; MONOLAYERS; TISSUE;

ECHO CONTRAST AGENT; MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY; PERSISTENT LEFT VENTRICULAR OPACIFICATION;

ECHOCARDIOGRAPHY;

BY 963; ECHO CONTRAST MEDIUM; PERFLUOROPENTANE;

AREA UNDER THE CURVE; ARTICLE; CONTRAST ECHOCARDIOGRAPHY; DENSITOMETRY; DOG; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG TOLERABILITY; HEART LEFT VENTRICLE; HEART MUSCLE; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; TISSUE CHARACTERIZATION;

AIR; ANIMALS; CONTRAST MEDIA; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ECHOCARDIOGRAPHY; FLUOROCARBONS; HEART VENTRICLES; INJECTIONS, INTRAVENOUS; PHOSPHATIDYLCHOLINES; TIME FACTORS;

EID: 0032970496     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-5629(99)00017-4     Document Type: Article

References (24)

1. Beller K.D. Noninvasive recording of left-ventricular function in the conscious dog and intraoperative representation of myocardial perfusion using Doppler echocardiography. 7th Freiburg Focus on Biomeasurement. 1991;110-121 Biomeßtechnik-Verlag, Buchenbach.
2. Beppu S., Matsuda H., Shishido T., et al. Prolonged myocardial contrast echocardiography via peripheral venous administration of QW 3600 injection (EchoGen®) Ist efficacy and side effects . J Am Soc Echocardiogr. 10:1997;11-24.
3. von Bibra H., Sutherland G., Becher H., Neudert J., Nihoyannopoulos P. Clinical evaluation of left heart Doppler contrast enhancement by a saccharide-based transpulmonary contrast agent. J Am Coll Cardiol. 25:1995;500-508.
4. Bos L.J., Piek J.J., Spaan J.A. Background subtraction from time intensity curves in videodensitometry a pitfall in flow assessment using contrast echocardiography . Ultrasound Med Biol. 21:1995;1211-1218.
5. Bubenheimer P., Beller K.-D., Schaffer P. Two-dimensional and colour Doppler contrast echo-cardiography of the right and left heart with the ultrasound contrast medium BY 963 after intravenous administration in conscious dogs. Eur J Ultrasound. 2:1995;301-312.
6. de Jong N., Hoff L., Skotland T., et al. Absorption and scatter of encapsulated gas filled microspheres theoretical considerations and some measurements . Ultrasonics. 30:1992;95-103.
7. Dittrich H.C., Bales G.L., Kuvelas T., Hunt R.M., McFerran B.A., Greener Y. Myocardial contrast echocardiography in experimental coronary artery occlusion with a new intravenously administered contrast agent. J Am Soc Echocardiogr. 8:1995;465-474.
8. Firschke Ch, Lindner J.R., Wei K., et al. Myocardial perfusion imaging in the setting of coronary artery stenosis and acute myocardial infarction using venous injection of a second generation echocardiographic contrast agent. Circulation. 96:1997;959-967.
9. Goldberg B.B., Liu J.B., Forsberg F. Ultrasound contrast agents A review . Ultrasound Med Biol. 20:1994;319-333.
10. Ismail S., Jayaweera A.R., Skyba D.M., et al. Integrated backscatter and digital acquisition during myocardial contrast echocardiography Is there an advantage over conventional echocardiography for intracoronary injections . J Am Soc Echocardiogr. 8:1995;453-464.
11. Kaps M., Schaffer P., Beller K.-D., Seidel G., Bliesath H., Wurst W. Phase I Transcranial echo contrast studies in healthy volunteers . Stroke. 26:1995;2048-2052.
12. Kaul S., Jayaweera A.R., Glasheen W.P., et al. Myocardial contrast echocardiography and the transmural distribution of flow a critical appraisal during myocardial ischemia not associated with infarction . J Am Coll Cardiol. 20:1992;1005-1016.
13. Kenner T., Harnoncourt K. Die molmasse der atemluft. Atemw-Lungenkrkh. 21:1995;454-456.
14. Leischik R., Beller K.D., Erbel R. Comparison of a new intravenous echo contrast agent (BY963) with albunex for opacification of left ventricular cavity. Basic Res Cardiol. 91:1996;101-109.
15. Meerbaum S. Microbubbles fluid dynamics of echocontrast. Nanda N.C., Schlief R., Goldberg B.B. Advances in echo imaging using contrast enhancement. 2nd edition. 1997;11-38 Kluwer Academic Publishers, Dordrecht.
16. Ophir J., Parker K.J. Contrast agents in diagnostic ultrasound. Ultrasound Med Biol. 15:1989;319-333.
17. Porter T.R., Xie F., Kricsfeld A., et al. Improved endocardial border resolution during dobutamine stress echocardiography with intravenous sonicated dextrose albumine. J Am Coll Cardiol. 23:1994;1440-1443.
18. Porter T.R., Xie F., Kilzer K. Intravenous perfluoropropane-exposed sonicated dextrose albumin produces myocardial ultrasound contrast that correlates with coronary blood flow. J Am Soc Echocardiog. 8:1995;710-718.
19. Ragosta M., Camarano G., Kaul S., et al. Microvascular integrity indicates myocellular viability in patients with recent myocardial infarction new insights using myocardial contrast echocardiography . Circulation. 89:1994;2562-2569.
20. Skyba D.N., Camaro G., Goodman N.C., et al. Hemodynamic characteristics, myocardial kinetics and microvascular rheology of FS-069, a second-generation echocardiographic contrast agent capable of producing myocardial opacification from a venous injection. J Am Coll Cardiol. 28:1996;1292-1300.
21. Strauss A., Beller K.D. Arterial parameters under echo contrast enhancement. Eur J Ultrasound. 5:1997;31-38.
22. Strauss A., Beller K.D. Contrast ultrasonography for 2-D opacification of heart cavities, peripheral vessels, kidney and muscle. Ultrasound Med Biol. 23:1997;975-982.
23. Villanueva F.S., Glasheen W.P., Sklenar J., Kaul S. Characterization of spatial patterns of flow within the reperfused myocardium by myocardial contrast echocardiography implication in determining extent of myocardial salvage . Circulation. 88:1993;2596-2606.
24. Wilson B., Shung K.K., Hete B., Levene H., Barnhart J.L. A feasibility study on quantitative myocardial perfusion with albunex, an ultrasonic contrast agent. Ultrasound Med Biol. 19:1993;181-191.