Cardiovascular regulation during insulin infusion into the carotid or vertebral artery in dogs

Journal of Hypertension

Volumn 17, Issue 2, 1999, Pages 251-260

  Hildebrandt, Drew A ^a,b   Smith Jr , Manis J ^a,b   Hall, John E ^a,b  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Blood pressure; Cardiac output; Heart rate; Total peripheral vascular resistance

Indexed keywords

GLUCOSE; INSULIN; PANCREAS HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE; BRAIN CIRCULATION; CARDIOVASCULAR FUNCTION; CAROTID ARTERY; CENTRAL NERVOUS SYSTEM; CONTINUOUS INFUSION; CONTROLLED STUDY; DOG; FEMALE; GLUCOSE INFUSION; HEART OUTPUT; HEART RATE; HEMODYNAMICS; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN INFUSION; INTRAARTERIAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SYMPATHETIC TONE; TACHYCARDIA; VERTEBRAL ARTERY;

EID: 0032970237     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199917020-00010     Document Type: Article

References (41)

1. Chiang BN, Perlman LV, Epstein FH. Overweight and hypertension: a review. Circulation 1969; 39:403-421.
2. Kannel WB, Brand N, Skinner JJ Jr, Dawbor TR, McNamara PM. The relation of adiposity to blood pressure and development of hypertension. Ann Intern Med 1967; 67:48-59.
3. Hall JE, Renal and cardiovascular mechanisms of hypertension in obesity. Hypertension 1994; 23:381-394.
4. Hall JE, Brands MW, Dixon WN, Smith MJ Jr. Obesity-induced hypertension: renal function and systemic hemodynamics. Hypertension 1993; 22:292-299.
5. Tuck ML. Obesity, the sympathetic nervous system, and essential hypertension. Hypertension 1992; 19 (Suppl 1):167-177.
6. Landsberg L, Krieger DR, Obesity, metabolism, and the sympathetic nervous system. Am J Hypertens 1989; 2 (Suppl):125S-132S.
7. Sowers JR, Whitfield LA, Catania RA, Stern N, Tuck ML, Dornfield L, et al. Role of the sympathetic nervous system in blood pressure maintenance in obesity. J Clin Endocrinol Metab 1982; 54:1181-1187.
8. Young JB, Landsberg L. Diet-induced changes in sympathetic nervous system activity: possible implications for obesity and hypertension. J Chronic Dis 1982; 35:879-886.
9. Anderson EA, Sinkey CA, Lawton WJ, Mark AL. Elevated sympathetic nerve activity in borderline hypertensive humans: evidence from direct intraneuronal recordings. Hypertension 1989; 14:177-183.
10. Hall JE, Van Vliet BN, Torrey C, Garrity CN, Brands MW. Adrenergic mechanisms in obesity-induced hypertension [abstract]. FASEB J 1993; 7:A1086.
11. Kassab S, Kato T, Wilkins FC, Chen R, Hall JE, Granger JP. Renal denervation attenuates the sodium retention and hypertension associated with obesity. Hypertension 1995; 25 (part 2):893-897.
12. Landsberg L, Hyperinsulinemia: possible role in obesity-induced hypertension. Hypertension 1992; 19 (Suppl 1):161-166.
13. Anderson EA, Hoffman RP, Balon TW, Sinkey CA, Mark AL. Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 1991; 87:2246-2252.
14. Berne C, Fagius J, Pollare T, Hjemdahl P. The sympathetic response to euglycaemic hyperinsulinaemia: evidence from microelectrode nerve recordings in healthy subjects. Diabetologia 1992; 35:873-879.
15. Frandsen HA, Snitker S, Christensen NJ, Madsbad S. No differential effects of porcine and human insulin on muscle sympathetic nerve activity during euglycaemia or hypoglycaemia. Clin Physiol 1996; 16:9-21.
16. Liang C-S, Doherty JU, Faillace R, Maekawa K, Arnold S, Gavras H, et al. Insulin infusion in conscious dogs: effects on systemic and coronary hemodynamics, regional blood flows, and plasma catecholamines. J Clin Invest 1982; 69:1321-1336.
17. Pereda SA, Eckstein JW, Abboud FM. Cardiovascular responses to insulin in the absence of hypoglycemia. Am J Physiol 1962; 202:249-252.
18. Muntzel MS, Morgan DA, Mark AL, Johnson AK. Intracerebroventricular insulin produces nonuniform regional increases in sympathetic nerve activity. Am J Physiol 1994; 267:R1350-R1355.
19. Nishimura M, Takahashi H, Matsusawa M, Ikegaki I, Nakanishi T, Yoshimura M. The effects of insulin and insulin-like materials in the brain on central cardiovascular regulation, with special reference to the central effects of sodium chloride. J Hypertens 1991; 9:509-517.
20. Hall JE, Coleman TG, Mizelle HL, Smith MJ Jr. Chronic hyperinsulinemia and blood pressure regulation. Am J Physiol 1990; 258:F722-F731.
21. Brands MW, Mizelle HL, Gaillard CA, Hildebrandt DA. Hall JE, The hemodynamic response to chronic hyperinsulinemia in conscious dogs. Am J Hypertens 1991; 4:164-168.
22. Baron AD. Hemodynamic actions of insulin. Am J Physiol 1994; 267;E187-E202.
23. Landsberg L. Insulin sensitivity in the pathogenesis of hypertension and hypertensive complications. Clin Exp Hypertens 1996; 18:337-346.
24. Committee on the Care and Use of Laboratory Animals. Guide for the care and use of laboratory animals, NIH Publ no. 85-23. Washington, DC: NIH; 1985.
25. Herd JA, Barger AC. Simplified technique for chronic catheterization of Wood vessels, J Applied Physiol 1964; 19:791-794.
26. Montani J-P, Mizelle HL, Van Vliet BN, Adair TH. Advantages of continuous measurement of cardiac output 24 h a day. Am J Physiol 1995; 269:H696-H703.
27. Christensen GC, Evens HE, Miller's anatomy of the dog. Philadelphia: WB Saunders; 1979.
28. Reid IA, Brooks VL, Rudolf CD, Keil LC. Analysis of the actions of angiotensin on the central nervous system in conscious dogs. Am J Physiol 1982; 243:R82-R91.
29. 2n on the carotid arterial blood flow, cerebrospinal fluid pressure, and intraocular pressure in dogs. Proc Soc Exp Biol Med 1972; 140:866-869.
30. Dunnett CW. A multiple comparison procedure for comparing several treatments with a control. J Am Stat Assoc 1955, 50:1096-1121.
31. DiFronzo RA. The effects of insulin on renal sodium metabolism. Diabetologia 1981; 21:165-171.
32. Muntzel MS, Beltz T, Mark AL, Johnson AK. Anteroventral third ventricle lesions abolish lumbar sympathetic responses to insulin. Hypertension 1994, 23 (part 2):1059-1062.
33. Hall JE, Brands MW, Kivlighn SD, Mizelle HL, Hildebrandt DA, Gaillard GA. Chronic hyperinsulinemia and blood pressure: interaction with catecholamines? Hypertension 1990; 15:519-527.
34. Brands MW, Hildebrandt DA, Mizelle HA, Hall JE. Sustained hyperinsulinemia increases arterial pressure in conscious rats. Am J Physiol 1991; 260:R764-R768.
35. Brands MW, Harrison DL, Keen HL, Gardner A, Shek EW, Hall JE. Insulin-induced hypertension in rats depends upon an intact renin-angiotensin system. Hypertension 1997; 29:1014-1019.
36. Keen HL, Brands MW, Smith MJ Jr, Shek EW, Hall JE. Inhibition of thromboxane synthesis attenuates insulin hypertension in rats. Am J Hypertens 1997; 10:1125-1131.
37. Sawicki PT, Heinemann L, Starke A, Berger M. Hyperinsulinaemia is not linked with blood pressure elevation in patients with insulinoma. Diabetologia 1992; 35:649-652.
38. Keen HL, Brands MW, Alonzo-Galacia M, Hall JE. Chronic adrenergic blockade does not prevent hyperinsulinemia-induced hypertension in rats. Am J Hypertens 1996; 9:1192-1199.
39. Hausberg M, Hoffman RP, Somers VK, Sinkey CA, Mark AL, Anderson EA. Contrasting autonomic and hemodynamic effects of insulin in healthy elderly versus young subjects. Hypertension 1997; 29:700-705.
40. Laakso M, Edelman SV, Brechtel G, Baron AD. Impaired insulin-mediated skeletal muscle blood flow in patients wilh NIDDM. Diabetes 1992; 41:1076-1083.
41. Creager MA, Liang C-S, Coffman JD. Beta adrenergic-mediated vasodilator response to insulin in the human forearm. J Pharmacol Exp Ther 1985; 235:709-714.